In-Vitro Anti-oxidant And Antimicrobial Study of Ficus Hispida

Ficus hispida L. belongs to the Moraceae family and is used by the maaiba trible (indigenous medicine - man of Manipur, India) as an indigenous traditional medicine. Present study deals with the successive extraction of the aerial parts of Ficus hispida and in-vitro screening of anti-oxidant and anti-microbial activity. The phytochemical screening of the methanol extract of Ficus hispida shows the presence of secondary metabolite groups like alkaloid, phenolic compounds, flavonoid, glycosides, protein etc. Phenolic compounds are commonly found in both edible and nonedible plants and are responsible for various medicinal activities of plants, so our study is based on determining antioxidant activity and anti-microbial activity. Beside these, we also measured the total flavonoid and total phenolic content of the respective sample to understand the effect of polyphenolic compound on different pathophysiological state associated with high free radical production. The in-vitro investigation proves the efficiency of this plant in various diseases states

In Silico Molecular Modeling and Structural Analysis of Peroxidase Enzymes from five different plants species

ABSTRACT Upon attacked by pathogens, plants defend themselves by producing array of defense related molecules. Plant peroxidase enzymes are about 300-350 residue long and have multiple isoenzymes that differ in substrate specificity and localization within the plant. In this study, 3D structure of peroxidase enzymes from five different plants was predicted by homology modeling method. The quality of the 3D structure of the model was confirmed by various web based validation programs. When compared secondary and tertiary structure of the model, it showed two peroxidase signature domains (PEROXIDASE_1 and PEROXIDASE_2) are present in the central region. Degree of sequence conserveness showed that sequence size differences do not make any impact on their basic functions

Frequency based analysis of collective aggregation rules

A new property for collective aggregation rules called positive discrimination is introduced. This property is satisfied by many anonymous and neutral collective aggregation rules. We discuss unimodal profiles (or distributions) for which this property on its own determines the outcome as the mode of a unimodal distribution. We investigate relaxations of this unimodal distribution condition and show that the Condorcet consistent rules as well as the Borda rule and the plurality rule have the mode as the outcome at such profiles. Further, we show, by an example, how the addition of unimodal profiles and the property of positive discrimination can help to determine an outcome in the case of a large number of voters. (C) 2020 Elsevier B.V. All rights reserved

(Invited) Engineering Nanoporous Iridium Microstructures for Stable Oxygen Evolution Electrocatalysis in Acid Media

Water splitting through PEM electrolysis provides promising route for renewable energy storage and production of high purity hydrogen and oxygen gases. Iridium oxide which is the only stable metal oxide that can evolve oxygen at the anode with reasonable activity is typically alloyed with less expensive transition metals to make high surface area Ir alloy nanostructures for commercially viable oxygen evolution reaction (OER) electrocatalysts. The chemical and morphological stability of such alloy nanostructures at anodic potential in acid is still a major concern for long term electrolysis. Here, we show dealloying as an appropriate method to synthesize free standing high surface area, oxide skinned nanoporous bimetallic Ir (np-Ir) alloys for efficient and stable OER electrolysis in acid media. The metallic core and absence of any binder/support result in low electrode and charge transfer resistance; ultimately giving rise to lower overpotential and much improved ECSA (electrochemically active surface area) normalized current densities compared to traditional IrO2 electrocatalysts for acidic OER. We also demonstrate with a proper acid concentration in the dealloying electrolyte and a requisite atomic fraction of iridium in the precursor alloy, dealloying gives rise to nanoporous microsheets of core shell Ni-Ir alloy. Compared to the IrO2 nanoparticles, the nanoporous Ir microstructures offer high carrier mobility because of the interconnected ligamentous structure that provides easy supply of electrons on the iridium oxide surface required to break the water molecule. Overall, the nanoporous Ir obtained through dealloying exhibits low overpotential and stable OER electrolysis in acid media. </jats:p

Locating a public good on a sphere

It is shown that in a model where agents have single-peaked preferences on the sphere, every Pareto optimal social choice function that is strict or coalitional strategy-proof, is dictatorial