Volatile bioactive compounds from marine macro-algae and their pharmacological properties

832-842The present study is aimed at identification of bioactive compounds and their pharmacological properties of four macro-algae (Hydropuntia edulis, Halymenia venusta, Ulva lactuca and Padina gymnospora) from the Hare Island, Tuticorin district of Tamil Nadu, India. The characterization of ethanol extracted compounds was done using GC-MS techniques. The major secondary metabolites such as alkaloids, phenol, saponins, flavonoids, steroids, terpenoids and tannins were recorded from all the algal samples. The numbers of major volatile compounds recorded in the GC-MS analysis are 32, 19, 8 and 14 in H. edulis, H. venusta, U. lactuca and P. gymnospora, respectively. All these identified compounds could be of therapeutic values for many acute and chronic diseases and disorders. These secondary metabolites belong to alkanes, aliphatic amines, aromatics, aldehydes, 1°, 2° amines and ketone groups. Many of these characterized compounds could be used for therapeutic purposes

Characterization of Antibacterial Phytochemicals from Three Coastal Sand Dunes in Chennai Beaches

Ipomoea sp and Spinifex sp most widely distributed salt tolerant plants and usually thrive in harsh condition .The present investigation was carried out to determine the antibacterial activity as well as phytochemical analysis using a GC-MS technique.The different solvent extracts ( ethyl acetate and methanol) of the plant were tested for antibacterial activity against human pathogens.The result highlighted that the antibacterial activity of ethyl acetate extract of Spinifex sp. panicle was especially active against P. aeruginosa(mean ; 21mm) and E. faecalis(mean ; 17mm). The extract concentration providing 50% inhibition (IC 50 ) was calculated from the graph of inhibition percentage plotted against extract concentration (25-250 μg/mL) and IC 50 is found to be 100 μg/mL which showed 53.3% inhibition ( 0.035 O.D) for E .faecalis. IC 50 is found to be 225 μg/mL which showed 55.35% inhibition( 0.025 O.D) for P. aeruginosa. The phytochemical analysis of the crude extract revealed the presence of alkaloid, flavonoid, sugar, anthraquinones, saponines and phenolic compounds.In TLC, prominent bands were obsevered in Hexane and ethyl acetate combination of concentration 6:4.In bioautography, a clear zone was seen in the E. faecalis plate amended with agar