Semantic Categorization Of Online Video

As internet users are increasing day by day, the users of video-sharing site are also increasing. Video-sharing is becoming more and more popular in e-learing, but the current famous websites like youtube are not structured when it come to serving the purpose of providing educational videos for preschool and high school students. There is a need to fill building more educationally focused video site, where the content is more structured, easy to use, support both direct search and browsing, and follow a particular curriculum for preschool and high school students. This report discuss the issues like categorization and search interface of these sites and propose alternatives to existing ones out there. In this project, I have built an educational website for preschool, high school, and college level students concentrating on improved categorization and search interface of the site. This report provides detail description of my system and the results of comparison between my site and youtube. supraj

Nonstationarity and Nonlinearity in the US Unemployment Rate: A Re-examination

Conventional econometric tests cannot distinguish nonstationarity from nonlinearity because of the joint modeling of unit roots with threshold effects. Caner–Hansen (CH, 2001) provides a new test which for the first time can simultaneously test for both (without any prior assumption of stationarity). Their threshold unit root tests are more powerful than conventional Augmented Dickey-Fuller tests, especially when the true process is nonlinear. They look at unemployment among adult males, and find contrary to many previous studies, that it is a “stationary nonlinear threshold process”. This paper attempts to re-examine and reconfirm the CH methodology by using unemployment in the civilian labor force. We extend the data up to December 2004, to see if the results hold up to the recent turbulent times, when unemployment changed dramatically from 3.9 % (1999) to 6.2 % (2003). Our results support the premise that US unemployment is a stationary threshold autoregressive process.

Scientometric dimensions of technical reports from Bhabha Atomic Research Centre

Technical report is one of the media to record the scientific information generated by scientists and engineers, Bhabha Atomic Research Centre (BARC) published 554 technical reports during 1990-99 under the categories: External (373) and Internal (181), Engineering and technology generated 207 technical reports followed by chemistry, materials and earth sciences (129), while their interdisciplinary interactions resulted in 31 technical reports, Life and environmental sciences produced 42 technical reports,' followed by Physics (16),' Other aspects of nuclear and non-nuclear energy (6); Isotopes, isotope and radiation applications (4), Technical reports in subjects outside the scope of nuclear science and technology were 69, Scientometric analysis of these reports has been carried Out for physical bibliographic characteristics, authorship collaboration, inter-divisional collaboration, inter-institutional collaboration activities and content analysis, Types of documents referenced in the technical reports indicated first rank for journal articles, followed by books, technical reports, conference papers, standards/codes, personal communications, patents, theses, drawings, and lectures

Homi Jehangir Bhabha as a Knowledge Generating System: A Longitudinal Cognition Study

Quantitative analysis of the events of synchronous references in the research papers followed throughout the publishing career of an individual scientist revealed interesting highlights on the knowledge-generating-system. In the case study of Homi Jehangir Bhabha first quinquennium and fifth quinquennium of his research career had low Self-references; third quinquennium and fourth quinquennium had moderate Self-references; whereas second quinquennium had highest Self-references. The two major clusters of Self-references occurring during the second and third quinquennium were indicators of active periods of knowledgegenerating and faster communications

IAP Regulation of Tumor Metastasis: A Dissertation

The dissemination of tumor cells to distant organs i.e. metastasis is an exceedingly complex process leading to 90% of all cancer deaths. Despite being so clinically important, little is known about this process that requires tumor cells to leave the primary tumor site, intravasate and transport through the blood stream, extravasate and colonize at secondary sites leading to distant metastases. Survivin, a member of the IAP (Inhibitor of Apoptosis) family with known functions in apoptosis and mitosis, is highly expressed in aggressive tumors and is associated with poor prognosis and adverse clinical outcome. But the mechanistic role of survivin in metastatic dissemination has not been investigated. In this study, we demonstrate an important and novel role of survivin in activating a broad gene expression program in tumor cells. Of particular importance is the upregulation of a distinct class of cell adhesion molecules, particularly fibronectin. This IAP mediated gene regulation requires synergistic intermolecular cooperation between survivin and its related cofactor molecule, XIAP that results in activation of NF-κB dependent fibronectin gene expression. The binding of fibronectin with its cognate cell surface receptors initiates outside–in signaling leading to the autocrine and paracrine activation of cell motility kinases, FAK and Src, in turn leading to enhanced tumor invasion and metastasis. The importance of survivin and XIAP in the process of metastasis has also been demonstrated in vivousing intrasplenic injections in mouse models. Overall this study is the first to place survivin upstream of transcriptional activation of gene expression particularly fibronectin. In addition, it also demonstrates the importance of survivin-XIAP complex in mediating NF-κB activation which in turn switches on the expression of various target genes involved in tumor metastasis. Hence this study dissects the upstream and downstream requirements of survivin- XIAP complex mediated tumor dissemination and metastasis. Significance of this Study The hallmark of end-stage cancer is metastasis, an incurable condition almost invariably associated with death from disease. Despite a better understanding of the metastatic process, and the identification of key gene expression requirements of this pathway, the development of anti-metastatic therapies has lagged behind, with no viable options being currently offered in the clinical setting. Our findings that Inhibitor of Apoptosis (IAP) proteins functions as metastasis-promoting genes independently of cell survival, but through activation of cell motility could have important ramifications for the broader application of IAP antagonists currently in early clinical trials, as novel anti-metastatic therapies

CoMaL Tracking: Tracking Points at the Object Boundaries

Traditional point tracking algorithms such as the KLT use local 2D information aggregation for feature detection and tracking, due to which their performance degrades at the object boundaries that separate multiple objects. Recently, CoMaL Features have been proposed that handle such a case. However, they proposed a simple tracking framework where the points are re-detected in each frame and matched. This is inefficient and may also lose many points that are not re-detected in the next frame. We propose a novel tracking algorithm to accurately and efficiently track CoMaL points. For this, the level line segment associated with the CoMaL points is matched to MSER segments in the next frame using shape-based matching and the matches are further filtered using texture-based matching. Experiments show improvements over a simple re-detect-and-match framework as well as KLT in terms of speed/accuracy on different real-world applications, especially at the object boundaries.Comment: 10 pages, 10 figures, to appear in 1st Joint BMTT-PETS Workshop on Tracking and Surveillance, CVPR 201

Use of p-charts to determine if shifts and teams are responsible in producing defective glasses at XYZ Company

Includes bibliographical references

Size Matters: Tiny Dots and Their Potential

In 1959, the physicist Richard Feynman wondered if the text of the Encyclopedia Britannica could be contained on the head of a pin. Today we are looking at the amazing potential of materials that are 10,000-1 million times smaller than the head of a pin. These nano and sub-micron scale “dots” have unique properties that make them candidates for applications in a wide range of fields, including medicine and defense. Susquehanna University students have been involved in research involving nanoparticles made of gold and silver, to name a few, and have also developed instrumentation to make “tiny dots” out of proteins that could potentially be used to repair damaged tissue

PHYTOREMEDIATION OF PHARMACEUTICAL PRODUCTSâ€

ABSTRACT:Objective: This study focuses on application of phytoremediation technology in remediation of some pharmaceutical products like antibiotics (ciprofloxacin) and hormones (progesterone and estrogen).Methods: Cicer arientum is well studied and documented plant for phytoremediation of heavy metals, in specific. Here we tried to focus this potential of this plant for the pharmaceutical products by UV-VIS Spectrophotometric method in Hoagland-Arnon solution.Results: The results implies that Cicer arientum can be used for phytoremediation of pharmaceutical products with an average of 60% of the pollutant being  remediated.Conclusion: The percentage remediation of  pollutants are 60, 64.66 and 63.3 of Ciprofloxacin, progesterone and estrogen, respectively by Cicer arientum.Keywords: Antibiotics, hormones, Cicer arientum, UV spectrophometre, pharmaceutical products

Personalized medicine: examining the current and future applications of pharmacogenetics and pharmacogenomics

There have been many scientific developments in the last century including the atomic bomb and DNA sequencing. Moreover, when human genome was sequenced in the early 2000s, it opened a new avenue to study disease and human development. Genetic tests have become an integral part for cancer diagnosis. Still, cancer therapy is decided based on the tumor genotype, the very definition of pharmacogenetic testing. More specifically, pharmacogenetics or pharmacogenomics is defined as variations in genes that can affect drug response. There has been great deal of research into pharmacogenetics and its potential fields for application. One such field is cardiology and cardiovascular disease. There are some promising researches that indicate genetic influence over drug response, such as the role of CYP2C19 over metabolism of a drug used for treating acute coronary disease and other cardiovascular issues. This is a great tool in the transition toward personalized medicine; however there are some logistical and social concerns over genetic tests; test administration, result accuracy and validity, data storage and security. Also, many patients were concerned with confidentiality, payment method and timely intervention. Also, implementation plans should include all areas, not just cities. Although there is potential for pharmacogenetic testing, many challenges have to be considered and addressed to ensure public confidence and proper use of the technique. Pharmacogenetics is a step towards individualized or personalized medicine; in-depth research prior to implementation will help tackle any challenges that may arise