Management of lateral end clavicle fractures-using lateral clavicle locking plate: a prospective study

Background: Lateral end clavicle fractures are one of the common upper limb fractures. They constitute 21–28% of all clavicle fractures. Of these 10–52% is displaced fractures. The management of fractures of lateral end clavicle remains debated and challenging. The objectivbe of this study is to evaluate the functional outcome following surgical treatment of unstable/displaced (Neer type II lateral clavicle fractures, and acromio-clavicular joint dislocations Rockwood grade III to V) lateral end clavicle fractures using lateral clavicle locking plate.Methods: It is a prospective study conducted in the orthopaedics department of GSL Medical College and General Hospital for a period of 3 years (April 2016 to March 2019) among a total of 60 patients.Results: About 23 (38.3%) belonged to 41–50 years age group, followed by 16 (26.7%) to 31–40 years age group and 13 (21.7%) to >51 years age group and 8 (13.3%) to 18–30 years age group. The time from trauma to surgery ranged from 0-15 days with a mean of 5 days and the mean operating time was 41 minutes ranging between 23-70 minutes. Mean duration to union was 13.33±2.126 weeks and the mean Constant Murley score was 88.56. Functional outcome at 6 months follow up was excellent in 8 (13.3%), good in 37 (61.7%), fair in 13 (21.7%) and poor in 2 (3.3%) patients.Conclusions: Although there is no consensus as to a “gold standard” fixation method for unstable distal clavicle fractures, satisfactory outcomes could be obtained using the lateral clavicle locking plate resulting in sufficient stabilization and good functional outcome

Pattern and pharmacotherapy of acute poisonings presenting to a tertiary care centre

Background: Acute poisoning, a therapeutic emergency and one of the common causes of morbidity and mortality globally. The rate of mortality in developed countries range from 1-2%, but in India it varies between 15-30%. According to World Health Organization (WHO), globally more than three million acute poisoning cases with 2,20,000 deaths occur annually. Most of the fatalities are due to the victim not reaching the hospital in time. This study aims to evaluate the pattern of acute cases of poisoning in tertiary care hospital attached to BMCRI.Methods: Prospective, observational study based on hospital records at tertiary care hospital (twelve months). Data regarding demographic profile and treatment was collected. Data was analyzed using descriptive statistics and SPSS-24.Results: Out of a total of 810 poisoning cases, 608 were included (381 poisoning, 138 drug overdose and 89 snake bite). Organophosphorus compounds (OPC) (131/608) and Aluminium phosphide (43/608) were the commonest poisons consumed in the age group 21-30 years. Sedative-hypnotics, non-benzodiazepine antiepileptics (non BZD AEDs) and paracetamol were common drug overdose cases. Snake bite accounted for 14.6%.Conclusions: OP compounds were the most common among poisons, while sedatives-hypnotics were frequently consumed drugs, followed by Snake bite. Young adults from urban areas were the common victims with suicidal intention. This reflects the need for stringent rules regarding the availability and sale of drugs and poisonous substances

Effect of Hypocaloric Stress on Body and Tissue Composition of Rats K

Rats fed ad libitum, a ration comprising fresh foods (F ration) for 10 days, were switched over to another ration consisting of processed foods (P ration) for a similar period. Thereafter, the animals were subjected to a 50 per cent diet restriction for a period of 10 days and rehabilitated either on F ration or P ration for an equal period. The results showed a decline in growth rate, food consumption and food efficiency ratio in the group fed ad libitum on P ration compared to that on F ration. Fifty per cent diet, restriction induced loss of body weight due to depletion of body fat. A fall in the gross weight of liver,kidney and epididymal fat pad along with a reduction in the contentsof lipid in liver and fat pad were also observed. Refeeding ofdiet-restricted rats induced hyperphagia and super-normal weight gainwith both rations. The data on liver triglycerides appeared to show anage-related rise which could be controlled by diet restriction to someextent. Feeding of P ration tended to predisperse to higher adiposetissue cholesterol attributable to higher fat content of this ration

Multiple molecular forms of human lactoferrin. Identification of a class of lactoferrins that possess ribonuclease activity and lack iron-binding capacity

Lactoferrin (Lf), the major iron-binding component of milk, also a major constituent of the specific granules of neutrophils involved in antimicrobial activity and a glycoprotein thought to play a role in regulatory functions in the hematopoietic system as well as other physiologic activities, is shown to occur in three isoforms. One, Lf-alpha, binds iron; the other two, Lf-beta and Lf-gamma, express potent RNase activity, but do not bind iron. The three isoforms are very similar or identical in Mr, pI, partial proteolytic peptide patterns, NH2-terminal amino acid sequence, and reactivity with mAbs and polyclonal antisera against the RNase and Lf, respectively. The finding of structurally similar but enzymatically distinct forms of Lf may be related to the diverse functions of the molecule

Characterization of the first hexacoordinate phosphorus compound with S→P←S bonds

The first example of a hexacoordinate phosphorus compound [S{6-t-Bu-4-Me-C6H2O}2]2P+(Cl-· C3H4N2) with two S→P bonds is reported. This compound can be construed as an oxophosphonium salt with double intramolecular coordination by sulfur atoms. X-ray structure reveals a facial arrangement of the ligands with two coordinating sulfur atoms cis to each other. The S→P distance of 2.334 (1) Å is one among very short coordinate bond distances between sulfur and phosphorus

FLOW ANALYSIS OF AN AXIAL COMPRESSOR

An axial fan is a type of a compressor that increases the pressure of the air flowing through it. The blades of the axial flow fans force air to move parallel to the shaft about which the blades rotate. In other words, the flow is axially in and axially out, linearly, hence their name. The design priorities in an axial fan revolve around the design of the propeller that creates the pressure difference and hence the suction force that retains the flow across the fan. The main components that need to be studied in the designing of the propeller include the number of blades and the design of each blade. Their applications include propellers in aircraft, helicopters, hovercrafts, ships and hydrofoils. They are also used in wind tunnels and cooling towers. The materials used for axial flow fan impellers are aluminum or mild steel. The main disadvantages of using metallic impellers are high power consumption & high noise levels with lesser efficiency. To reduce these problems, fans are fabricated by using composite materials In this thesis, axial flow fans 3 models with 8, 9 and 10 blades are designed in 3D modeling software solid works by using Static and CFD analysis is done on the 3 models using the materials Stainless steel, S2 Glass Epoxy and Kevlar. By observing the results from ANSYS, for all materials, the analyzed stress values are less than their respective yield stress values, so using all the three materials is safe  under given load conditions. The strength of the composite material S2 Glass epoxy is more than that of other 2 materials Stainless Steel, Kevlar. By observing the analysis results, the displacement and stress values are less when 9 blades are used. Composite material S2 Glass epoxy with 9 blades is better than other two materials

Studies on feasibility of sustainable quality seed potato production technology and development of supply chain for the benefit of small and marginal potato growers of Karnataka

Management of aphid vectors in potato is important for the production of quality seed potato. Aphids are the major vectors of many potato viruses which transmit viral diseases limiting the seed potato production. To explore the area with aphid free/low population a weekly aphid observation was made in major potato growing areas of Chikkaballapur and Chickmagalur districts during rabiand kharif seasons to assess the build-up trends on the standing crop using aphid-leaf count and catches of yellow water pan and yellow sticky traps. Aphid population was below threshold level in the areas surveyed, however in Chickmagalur aphid build-up was erratic due to heavy rain fall followed by dry spells. Harvested potato in Chikkaballapur was treated and stored in cold storage for three months. During June, 50 per cent of the seed stock was transported to Chickmagalur area for planting in kharif season and remaining seed was used for planting in Chikkaballapur area during rabi season. In Chickmagalur, the harvested and treated seed was stored in low cost country potato store for three months and 50 per cent seed from warehouse was transported to Chikkaballapur for rabi planting and remaining seed was planted in Chickmagalur area during November thereby saving nearly 40 per cent of seed cost. Thus, the feasibility supply chain has been established making the local potato growers self-sustainable in quality seed potato production resulting in 30-40 percent seed requirement met locally produced quality seed and non-traditional areas will be brought under potato cultivation. The breeder seed was multiplied under low cost insect proof net houses during rabi season in Chikkaballapur area, harvested seed was stored in cold storage thereafter distributed among the local potato growers for planting during kharif season in Chickmagalur area