Health Profession Student’s Readiness Towards Online Learning as a Component of Blended Learning

Objectives: The objectives of this study were to identify the entry-level health profession students’ perception and readiness to adopt online learning as a component of blended learning (BL). Methods: A cross sectional survey using a structured questionnaire was administered using Google forms. Entry level Health professionals’ education (HPE) graduate students of a higher education institute in India completed the survey (N= 628). The questionnaire was developed from the literature and content validated by experts. Ethics clearance was obtained from the Institutional ethics committee. Results: Out of 628 responses, 603 fully completed questionnaires were included for analysis. Of the participants, 98 % owned a smartphone, whereas 67% possessed either a laptop or a stationary computer. 60 % of the respondents reported at least one hour of internet access per day for learning purposes. Most of the participants were comfortable in accessing online learning materials and interacting with peers. The majority of the participants (77.4%) were willing to spend 10 to 20 hours per week on online learning. Conclusion: Entry Level HPE graduate students were ready to adopt online learning as a component of BL. Providing necessary infrastructure and creating online learning materials needs to be considered

Towards cleaner degreasing method in industries: ultrasound-assisted aqueous degreasing process in leather making

Studies on ultrasound-assisted processes are gaining importance due to its effectiveness and facilitating green method in processing. Degreasing of skin/hide prior to tanning process is an important unit operation. Presence of large amounts of natural fat at the interior of skin/hide matrix makes degreasing process a challenging one. Conventionally, organic solvent and/or detergent based degreasing process are employed leading to environmental problems. In the present paper, the use of power ultrasound in aqueous degreasing process has been studied and compared with different degreasing systems. Glutaraldehyde pre-tanning has also been employed for carrying out the degreasing process at ultrasonic bath temperature. The results indicate that there is a significant increase in the degreasing efficiency due to the application of ultrasound. About 2-fold increase in fat removal has been observed due to the use of ultrasound as compared to control under the given process conditions. Comparing the degreasing efficiencies of the solvent with aqueous based ultrasonic processes, about 80% of the solvent degreasing efficiency could be obtained for aqueous degreasing process. This novel ultrasonic process helps in making aqueous degreasing process a viable option, which is eco-friendly even dispensing with temperature control measures

Studies on the use of power ultrasound in solid-liquid myrobalan extraction process

Focus on eco-friendly processing techniques makes vegetable tanning a viable option in leather processing and establishes the subsequent need for the more efficient methods of extraction in tannin manufacture. Application of ultrasound has been tried in the extraction of tannins from myrobalan nuts in order to improve the extraction efficiency, to perform the extraction under milder process conditions and to reduce the processtime.Theinfluenceofprocessparameterssuchasultrasonicoutputpower,timeandtemperaturehasbeenstudied.Scale-uptrialsandthe use of ultrasound in pulse mode have also been attempted. The results show that a three- to fivefold improvement is possible with ultrasonic output from 20 to 100 W. Extraction efficiency has been calculated from the maximum extractable materials from myrobalan nuts. Extraction efficiencyisfoundtobe90%forultrasound,100Wwithoutexternalheatingascomparedto77%forcontrolprocessat70 Cfor4 h.Therefore, ultrasound could be employed even dispensing with provision for temperature controls. The use of ultrasound in pulse mode offered 70% extraction efficiencyof continuous mode. Scale-up trials indicate that there exists an optimum ultrasonic output power depending on the amount ofnutsused, toachievebetter extraction efficiency.Theeffectivenessofultrasonicallyextractedtanninsolutionhasalsobeentestedinthetanning process for its applicability. The degree of tanning efficacy has been assessed by shrinkage temperature measurement. The results indicate that ultrasonically extracted tannin solution is suitable for tanning process. Therefore, application of ultrasound in tannin extract manufacture is a viable option with added advantages. 2006 Elsevier Ltd. All rights reserved

Newer initiatives under national tuberculosis elimination programme

National Tuberculosis Elimination Programme (NTEP) is a Centrally Sponsored Scheme being implemented under the aegis of the National Health Mission with resource sharing between the State Governments and the Central Government. The Government of India has committed to achieving the SDG goal of eliminating tuberculosis (TB) in the country by 2025, five years ahead of the Global Target. In light of this ambitious target and to accelerate momentum towards the ultimate goal, an appropriate and representative change in the name of the programme was imperative, and it was decided to rename the Revised National Tuberculosis Control Program (RNTCP) as NTEP [1]

Characterization of CYP76M5–8 Indicates Metabolic Plasticity within a Plant Biosynthetic Gene Cluster

Recent reports have revealed genomic clustering of enzymatic genes for particular biosynthetic pathways in plant specialized/secondary metabolism. Rice (Oryza sativa) carries two such clusters for production of antimicrobial diterpenoid phytoalexins, with the cluster on chromosome 2 containing four closely related/homologous members of the cytochrome P450 CYP76M subfamily (CYP76M5–8). Notably, the underlying evolutionary expansion of these CYP appears to have occurred after assembly of the ancestral biosynthetic gene cluster, suggesting separate roles. It has been demonstrated that CYP76M7 catalyzes C11α-hydroxylation of ent-cassadiene, and presumably mediates an early step in biosynthesis of the derived phytocassane class of phytoalexins. Here we report biochemical characterization of CYP76M5, -6, and -8. Our results indicate that CYP76M8 is a multifunctional/promiscuous hydroxylase, with CYP76M5 and -7 seeming to provide only redundant activity, while CYP76M6 seems to provide both redundant and novel activity, relative to CYP76M8. RNAi-mediated double knockdown of CYP76M7 and -8 suppresses elicitor inducible phytocassane production, indicating a role for these monooxygenases in phytocassane biosynthesis. In addition, our data suggests that CYP76M5, -6, and -8 may play redundant roles in production of the oryzalexin class of phytoalexins as well. Intriguingly, the preceding diterpene synthase for oryzalexin biosynthesis, unlike that for the phytocassanes, is not found in the chromosome 2 diterpenoid biosynthetic gene cluster. Accordingly, our results not only uncover a complex evolutionary history, but also further suggest some intriguing differences between plant biosynthetic gene clusters and the seemingly similar microbial operons. The implications for the underlying metabolic evolution of plants are then discussed

Tanscriptomic Study of the Soybean-Fusarium virguliforme Interaction Revealed a Novel Ankyrin-Repeat Containing Defense Gene, Expression of Whose during Infection Led to Enhanced Resistance to the Fungal Pathogen in Transgenic Soybean Plants

Fusarium virguliforme causes the serious disease sudden death syndrome (SDS) in soybean. Host resistance to this pathogen is partial and is encoded by a large number of quantitative trait loci, each conditioning small effects. Breeding SDS resistance is therefore challenging and identification of single-gene encoded novel resistance mechanisms is becoming a priority to fight this devastating this fungal pathogen. In this transcriptomic study we identified a few putative soybean defense genes, expression of which is suppressed during F. virguliformeinfection. The F. virguliforme infection-suppressed genes were broadly classified into four major classes. The steady state transcript levels of many of these genes were suppressed to undetectable levels immediately following F. virguliforme infection. One of these classes contains two novel genes encoding ankyrin repeat-containing proteins. Expression of one of these genes, GmARP1, during F. virguliforme infection enhances SDS resistance among the transgenic soybean plants. Our data suggest that GmARP1 is a novel defense gene and the pathogen presumably suppress its expression to establish compatible interaction

Power ultrasound in fatliquor preparation based on vegetable oil for leather application

In recent years, power ultrasound has taken a significant place in chemical and physical activities of the process industries as an effective and non-polluting method of activation. Oil in water emulsions known as fatliquors are used for the lubrication of tanned leather fibres to get softness and also to improve the strength properties. In the present study, ultrasound has been used as a tool for the preparation of fatliquor emulsion for application in leather fatliquoring process. An emulsion is a fine dispersion of one liquid in another liquid. Sulphation is one of the common methods followed to prepare fatliquor emulsion where sulphuric acid is used. In the conventional process, emulsifying agent is also added to increase the stability of oil in water emulsions. The emulsifying agents generally used are chemicals or metal soaps. The potential use of ultrasound in the preparation of stable oil in water emulsions dispensing with sulphation process and with the minimum use of emulsifying agent has been studied and reported in this paper. This process enjoys the benefit of less pollution load in the form of chemical entities. The studies included the effect of process parameters such as ultrasonic output power and amount of oil used. Fatliquor emulsion prepared using ultrasound has been applied in leather fatliquoring process and the strength properties of the leathers were assessed. Emulsion particle size, which is another important parameter for diffusion through leather, has been measured using Laser Diffraction Technique. The stability of the ultrasonically prepared fatliquor emulsion has been found to be good. The results indicate that ultrasound could be effectively utilized in the preparation of non-ionic fatliquor emulsion eliminating sulphuric acid and impart required properties in leather