Securing Public Places with PCA Based Recognition of Criminal Faces Detected from Surveillance CCTV Footage

This paper aims in ensuring the safety of common people at public places by using the existing CCTV systems which are deployed for the surveillance and to determine the security of that place, by identifying the suspicious faces that are captured and notifying the officials. The existing video surveillance systems capture data through CCTVs and store it in their database. After an unpredicted incident already taken place, these databases are used to recognize the culprit. Instead of this, the proposed system keeps a track of the live videos and exacts out frames from it after a fixed interval of time. These frames are then used to fetch faces and compare them with the criminal faces which are already stored in a suspicious faces database, using the feature extraction technique. If the comparison is successful, an alarm is generated which gives an alert about the presence of a criminal at that place. Various face detection algorithms and recognition techniques are used to identify the suspicious face in the crowd and enhances the safety of the public places

Unregulated Sale of Nimesulide in India

IntroductionNimesulide has been withdrawn from a number of countries. However it continues to be available over the counter in India.MethodsA survey of 1460 drug stores and 1531 families in India on their perceptions of the potential side effects of Nimesulide.Results A high proportion (78.96%) of the drug stores sold the drug without prescription from a licensed physician. More than one in four families (26.95%) preferred Nimesulide to other drugs. A relatively small proportion drug store owners and families (12.14% and 9.6% respectively) were aware of the potential adverse effects of this drug. DiscussionThere is an urgent need to tighten regulation of dangerous drugs freely available to Indian consumers. Further research to increase public awareness about drug side effects is required in order to reduce the potential for harm from under regulation

Kaposiform hemangioendothelioma in tonsil of a child associated with cervical lymphangioma: a rare case report

Kaposiform hemangioendothelioma (KHE) is an uncommon vascular tumor of intermediate malignant potential, usually occurs in the extremities and retroperitoneum of infants and is characterized by its association with lymphangiomatosis and Kasabach-Merritt phenomenenon (KMP) in certain cases. It has rarely been observed in the head and neck region and at times, can present without KMP. Herein, we present an extremely uncommon case of KHE occurring in tonsil of a child, associated with a neck swelling, but unassociated with KMP. A 2-year-old male child referred to us with history of sore throat, dyspnoea and right-sided neck swelling off and on, since birth, was clinicoradiologically diagnosed with recurrent tonsillitis, including right sided peritonsillar abscess, for which he underwent right-sided tonsillectomy, elsewhere. Histopathological sections from the excised tonsillar mass were reviewed and showed a tumor composed of irregular, infiltrating lobules of spindle cells arranged in kaposiform architecture with slit-like, crescentic vessels. The cells displayed focal lumen formation containing red blood cells (RBCs), along with platelet thrombi and eosinophilic hyaline bodies. In addition, there were discrete foci of several dilated lymphatic vessels containing lymph and lymphocytes. On immunohistochemistry (IHC), spindle cells were diffusely positive for CD34, focally for CD31 and smooth muscle actin (SMA), the latter marker was mostly expressed around the blood vessels. Immunostaining for HHV8 was negative and Ki-67 (proliferation marker) displayed focal positivity. Diagnosis of KHE was made. Platelet count was towards lower side of range. Postoperative imaging showed discrete, multiple fluid containing lesions in the right neck that were high on T2-weighed sequences, on magnetic resonance imaging (MRI) and ipsilateral intraoral mucosal growth. Fine needle aspiration cytology (FNAC) smears from neck swelling showed blood, fluid and lymphocytes. Possibility of a coexisting lymphangioma was considered. The patient was offered sclerotherapy and is on follow-up. This case forms the second documented case of KHE at this site, along with its unique association with neck lymphangioma. KHE has distinct histopathological features and can be sorted out from its other differentials like juvenile hemangioma and Kaposi's sarcoma. IHC stains are useful in substantiating a definite diagnosis

Needle(s) in the Haystack – Synchronous Multifocal Tumor Induced Osteomalacia

This is the author accepted manuscript. The final version is available from Endocrine Society via http://dx.doi.org/10.1210/jc.2015-3854MG is supported by the NIHR Cambridge Biomedical Research Centre

Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses

Aim : To describe various approaches of computed tomography (CT)-guided core biopsy and evaluate its ability to obtain adequate tissue for the assessment of mediastinal masses. Materials and Methods : Between February 2004 and October 2006, 83 percutaneous CT-guided biopsies of mediastinal lesions were performed on 82 patients under local anesthesia. Coaxial needles were used and minimum of 3-4 cores were obtained. Post-biopsy CT scan was performed and patients observed for any complications. Tissue samples were taken to Pathology Department in formalin solution. Results : From the 83 biopsies, adequate tissue for histological diagnosis was obtained in 80 (96%), and the biopsy was considered diagnostic. Of the 80 diagnostic biopsies, 74 biopsy samples were definitive for neoplastic pathology and 6 biopsy samples revealed no evidence of malignancy. There were no major complications. Minor complications were recorded in 5 patients. Conclusion : Percutaneous image-guided core biopsy of mediastinal lesions is an accurate, safe and cost-effective tool for the initial assessment of patients with mediastinal masses

Fake News Detection using Machine Learning

Everyone depends upon various online resources for news in this modern age, where the internet is pervasive. As the use of social media platforms such as Facebook, Twitter, and others has increased, news spreads quickly among millions of users in a short time. The consequences of Fake news are far-reaching, from swaying election outcomes in favor of certain candidates to creating biased opinions. WhatsApp, Instagram, and many other social media platforms are the main source for spreading fake news. This work provides a solution by introducing a fake news detection model using machine learning. This model requires prerequisite data extracted from various news websites. Web scraping technique is used for data extraction which is further used to create datasets. The data is classified into two major categories which are true dataset and false dataset. Classifiers used for the classification of data are Random Forest, Logistic Regression, Decision Tree, KNN and Gradient Booster. Based on the output received the data is classified either as true or false data. Based on that, the user can find out whether the given news is fake or not on the webserver

Non-Viral Vectors for Delivery of Nucleic Acid Therapies for Cancer

The research and development of non-viral gene therapy has been extensive over the past decade and has received a big push thanks to the recent successful approval of non-viral nucleic acid therapy products. Despite these developments, nucleic acid therapy applications in cancer have been limited. One of the main causes of this has been the imbalance in development of delivery vectors as compared with sophisticated nucleic acid payloads, such as siRNA, mRNA, etc. This paper reviews non-viral vectors that can be used to deliver nucleic acids for cancer treatment. It discusses various types of vectors and highlights their current applications. Additionally, it discusses a perspective on the current regulatory landscape to facilitate the commercial translation of gene therapy

Microwave ablation: How we do it?

Minimally invasive techniques such as Image guided thermal ablation are now widely used in the treatment of tumors. Microwave ablation (MWA) is one of the newer modality of thermal ablation and has proven its safety and efficacy in the management of the tumors amenable for ablation for primary and metastatic diseases. It is used in the treatment of primary and secondary liver malignancies, primary and secondary lung malignancies, renal and adrenal tumors and bone metastases. We wanted to share our initial experience with this newer modality. In this article we will describe the mechanism and technique of MWA, comparison done with RFA, advantages and disadvantages of MWA along with pre procedure workup, post procedure follow-up and review of literature