The Association between Pandemic Isolation and Glycemic Control and Biochemistry Parameters in Patients with Type 2 Diabetes

Objective: COVID-19 lockdown caused many people with chronic diseases to delay their follow-up and worsen their metabolic parameters. This study aimed to investigate the effect of the COVID-19 pandemic period on the glycemic control and biochemistry parameters of patients with type 2 diabetes mellitus (T2DM). Materials and methods: The data of 347 T2DM patients covering the period before and after the lockdown (March–June 2020) was retrospectively analyzed. HbA1c and fasting plasma glucose (FPG), renal function tests and microalbuminuria measurements were compared. All statistical analyses and power analysis were performed with IBM SPSS Statistics version 23.0. Results: Of 347 patients, 216 (62.2%) were female and the mean age was 58.82 ± 10.47 years. One hundred eighty five (53.3%) of the individuals have been using insulin and oral antidiabetic together and those treated with insulin alone were excluded at the data collection phase of the study. HbA1c, FPG, urea, creatinine, microalbumin in spot urine and alb/crea in spot urine increased in the pandemic period compared to pre-pandemic period, creatinine measurement decreased in spot urine (p < 0.05) except the ketone in urine between the two periods. HbA1c (r = 0.728, p < 0.01), creatinine (r = 0.8458, p < 0.01), microalbumin in spot urine (r = 0.773, p < 0.01) and spot urine alb/crea (r = 0.796, p < 0.01) measurements were highly, positive and statistically significant. Conclusions: As in all chronic diseases, T2DM patients should be followed up regularly in order to prevent morbidities in extraordinary situations such as pandemics

The Effect of Training About Sleep Hygiene on HbA1c Levels of Type 2 Diabetes Mellitus Patients: A Randomized Controlled Trial

Objective: In this study, we aimed to reveal whether training on sleep hygiene have an effect on blood glucose regulation of type 2 diabetes patients. Materials and methods: Those with even protocol numbers were included in the case group and those with odd numbers were included in the control group. Pittsburgh sleep quality index was applied face-to-face to all patients included in the study and at the first admission sleep hygiene training was given to the case group. HbA1c values were noted separately as first and second visit for both groups. Those with known sleep disorders and language or psychiatric problems that would prevent them from answering the questionnaire were excluded from the study. Differences between demographic and clinical features of groups were evaluated using chi-square and Student’s t-tests. Comparisons of the case and control groups before and after sleep hygiene training were evaluated using ANCOVA test adjusted for BMI and DM duration. Results: A total of 347 Type 2 diabetes patients included in this randomized controlled trial (113 case 234 control). Significant difference was observed in the HbA1c values measured before and after the training of the case group. The second mean HbA1c (8.13 ± 2.03 mmol/L) of the control group was significantly higher than the second mean HbA1c (7.51 ± 1.42 mmol/L) values of the case group (p = 0.004). Conclusions: Our study revealed that in addition to classical diabetes treatment, sleep hygiene training also has a positive effect on blood glucose regulation of patients

The impact of anemia on sleep quality in 15-49 years old women 15-49 Yaş kadınlarda aneminin uyku kalitesi üzerine etkisi

© 2018 by Türkiye Klinikleri.Objective: Sleep disorders which is approaching 40% of frequency in the general population, are closely related not only to physical and mental health, but also to work and social life. The lack of iron in children has been shown to cause sleep disturbances due to psychological disturbances and possible restlesslegs syndrome by affecting neurotransmitters. In adults, the number of studies showing an association between anemia and sleep disturbances is limited. This study aimed to investigate the effect of anemia on sleep quality in 15-49 years old women. Material and Methods: Our study was conducted with a total of 278 female patients aged 15-49 years who had total blood analyses within the last 1 month and had enough socio-cultural level to understand the questions asked. The hemoglobin level under 12 mg/dL was considered as anemia. The socio-demographic characteristics of the patients were analyzed. The general mood of the patients was rated with 10 point likerts cale (1 depressive, 10 very happy). Sleep characteristics were assessed by the Pittsburgh Sleep Quality Index (PSQI). The scores above 5 was considered good sleep quality. Results: Anemia was present in 37.8% of the patients. Total PSQI scores were similar in patients with and without anemia (6.5±3.1 vs 6.8±3.8, p=0.758). Anemia frequency was similar among patients with poor sleep and good sleep quality (36.4% vs 39.8%, p=0.559). However, body mass index in patients with poor sleep quality was higher than patients with good sleep quality (p<0.001). Smoking was more prevelant in patients with poor sleep quality (30.5% vs18.6%, p=0.026). Conclusion: Sleep quality is not affected by the presence of anemia. However, higher body mass index, poor general mood and smoking were found to be effective on sleep quality