The Ursinus Weekly, October 5, 1942

Over 135 students speed graduation in summer school • Abraham Hendricks succumbs at home after long illness • President McClure greets largest new enrollment Thursday in chapel • Founders\u27 Day program to honor Dr. Pfahler in dedication ceremony • College buildings to close at 5:30 • Work-study plan attracts 20 men • College opens buildings to 3 summer conclaves • Freshmen stagger through first week of mysteries at Ursinus • Miss Beck takes post as assistant librarian • Ursinus to participate in student war loan program • Swartley sets deadline • Five delegates attend Kanestaki conference • Y handbook guides puzzled freshmen • Letter received from Y\u27s Spanish refugee • Dr. McClure attends Colgate inauguration • The Ursinus College faculty • Here they are - largest enrollment of new students! • Summer sports feature intramurals and softball • Thirty-eight men out for football as second week of practice begins • Stevens is completing plans for inauguration of 150-lb. grid league • Grid schedule to include two home, two away games • Eight holdovers brighten outlook for girls hockey • Mules meet G-burg • Stevens enters his second year optimistically • Over twenty veterans report for soccer practice • Plea for humility made by Snyder, former Y prexy • R. C. Bartman promoted to captain in Navy • Carrying on the traditionhttps://digitalcommons.ursinus.edu/weekly/1739/thumbnail.jp

The Ursinus Weekly, November 30, 1942

Y launches drive at Ursinus today in behalf of WSSF • Louis Adamic, Messiah, and senior ball to make the week of December seventh one of the biggest of the college year • Community club\u27s program questions way toward peace • Grad\u27s sister dies in Boston tragedy • Faculty sends four to profs\u27 conclave • Y heads to address frosh • Analysis of women re-written to include artistic viewpoint • Personality and broad musical experience distinguish Dr. Philip • Debaters to meet tonight • Snell\u27s belles give bear sports first unblemished season in five years • Giants finish perfect season with 6-0 win over Packers • English Club to meet at McClure\u27s home tonight • Beautiful and historical trees cover campus; Dean Kline is nature expert of the collegehttps://digitalcommons.ursinus.edu/weekly/1747/thumbnail.jp

The Ursinus Weekly, January 11, 1943

How to find God is Koch\u27s subject at Y\u27s installation • College Who\u27s Who lists ten seniors in current edition • Forty will graduate on January 25 in first mid-year commencement • Weekly board fills editorial positions as nine graduate • Anders pre-med society to hear illustrated talk by noted dermatologist • Band pleases some in inter-frat ball • Biology Department receives microscope from Dr. Price • Men debaters open season • Ursinus queen\u27s coronation will replace May pageant • Clamer girls campused • First Ursinus casualty revealed by the Navy • English Club hears Dunant tell of Franco-Nazi hate • High schools to graduate pre-collegians in 3 1/2 years • Much feted freshman pledges flip the coin and cast the die • Coed wanted to fill post as Lantern manager • Curtain Club tryouts set for Wednesday • Blues in the night altered for duration • Wagner explains photos in color at chem meeting • Government seeks woman engineers • Lloyd M. Lebegern dies • Girls open season with Albright sextet at home this week • Jayvees begin practice under coach Hogeland • Rangers and snipers each win twice to take intramural basketball lead • Dribblers get new schedule • Former student gets a 109 • Heiges attends conventionhttps://digitalcommons.ursinus.edu/weekly/1750/thumbnail.jp

The Lantern Vol. 10, No. 2, April 1942

• Victory • Bobleenatris • Eve, the Apple Polisher • Fame • Rats! • Invasion • Saga of Deeptown • Candide • Wiffenpfooph-Hunting • War • The Conch • Pantomime • Rain • Song of the Little People • The Distant Drums • Advertisementshttps://digitalcommons.ursinus.edu/lantern/1026/thumbnail.jp

Risk Factors for Pre-Treatment Mortality among HIV-Infected Children in Rural Zambia: A Cohort Study

Many HIV-infected children in sub-Saharan Africa enter care at a late stage of disease. As preparation of the child and family for antiretroviral therapy (ART) can take several clinic visits, some children die prior to ART initiation. This study was undertaken to determine mortality rates and clinical predictors of mortality during the period prior to ART initiation.A prospective cohort study of HIV-infected treatment-naïve children was conducted between September 2007 and September 2010 at the HIV clinic at Macha Hospital in rural Southern Province, Zambia. HIV-infected children younger than 16 years of age who were treatment-naïve at study enrollment were eligible for analysis. Mortality rates prior to ART initiation were calculated and risk factors for mortality were evaluated.351 children were included in the study, of whom 210 (59.8%) were eligible for ART at study enrollment. Among children ineligible for ART at enrollment, 6 children died (mortality rate: 0.33; 95% CI:0.15, 0.74). Among children eligible at enrollment, 21 children died before initiation of ART and their mortality rate (2.73 per 100 person-years; 95% CI:1.78, 4.18) was significantly higher than among children ineligible for ART (incidence rate ratio: 8.20; 95% CI:3.20, 24.83). In both groups, mortality was highest in the first three months of follow-up. Factors associated with mortality included younger age, anemia and lower weight-for-age z-score at study enrollment.These results underscore the need to increase efforts to identify HIV-infected children at an earlier age and stage of disease progression so they can enroll in HIV care and treatment programs prior to becoming eligible for ART and these deaths can be prevented

Secular trends in pediatric antiretroviral treatment programs in rural and urban Zambia: a retrospective cohort study

<p>Abstract</p> <p>Background</p> <p>Since 2003 pediatric antiretroviral treatment (ART) programs have scaled-up in sub-Saharan Africa and should be evaluated to assess progress and identify areas for improvement. We evaluated secular trends in the characteristics and treatment outcomes of children in three pediatric ART clinics in urban and rural areas in Zambia.</p> <p>Methods</p> <p>Routinely collected data were analyzed from three ART programs in rural (Macha and Mukinge) and urban (Lusaka) Zambia between program implementation and July 2008. Data were obtained from electronic medical record systems and medical record abstraction, and were categorized by year of program implementation. Characteristics of all HIV-infected and exposed children enrolled in the programs and all children initiating treatment were compared by year of implementation.</p> <p>Results</p> <p>Age decreased and immunologic characteristics improved in all groups over time in both urban and rural clinics, with greater improvement observed in the rural clinics. Among children both eligible and ineligible for ART at clinic enrollment, the majority started treatment within a year. A high proportion of children, particularly those ineligible for ART at clinic enrollment, were lost to follow-up prior to initiating ART. Among children initiating ART, clinical and immunologic outcomes after six months of treatment improved in both urban and rural clinics. In the urban clinics, mortality after six months of treatment declined with program duration, and in the rural clinics, the proportion of children defaulting by six months increased with program duration.</p> <p>Conclusions</p> <p>Treatment programs are showing signs of progress in the care of HIV-infected children, particularly in the rural clinics where scale-up increased rapidly over the first three years of program implementation. However, continued efforts to optimize care are needed as many children continue to enroll in ART programs at a late stage of disease and thus are not receiving the full benefits of treatment.</p

Weight and height z-scores improve after initiating ART among HIV-infected children in rural Zambia: a cohort study

<p>Abstract</p> <p>Background</p> <p>Deficits in growth observed in HIV-infected children in resource-poor settings can be reversed with antiretroviral treatment (ART). However, many of the studies have been conducted in urban areas with older pediatric populations. This study was undertaken to evaluate growth patterns after ART initiation in a young pediatric population in rural Zambia with a high prevalence of undernutrition.</p> <p>Methods</p> <p>Between 2007 and 2009, 193 HIV-infected children were enrolled in a cohort study in Macha, Zambia. Children were evaluated every 3 months, at which time a questionnaire was administered, height and weight were measured, and blood specimens were collected. Weight- and height-for-age z-scores were constructed from WHO growth standards. All children receiving ART at enrollment or initiating ART during the study were included in this analysis. Linear mixed effects models were used to model trajectories of weight and height-for-age z-scores.</p> <p>Results</p> <p>A high proportion of study children were underweight (59%) and stunted (72%) at treatment initiation. Improvements in both weight- and height-for-age z-scores were observed, with weight-for-age z-scores increasing during the first 6 months of treatment and then stabilizing, and height-for-age z-scores increasing consistently over time. Trajectories of weight-for-age z-scores differed by underweight status at treatment initiation, with children who were underweight experiencing greater increases in z-scores in the first 6 months of treatment. Trajectories of height-for-age z-scores differed by age, with children older than 5 years of age experiencing smaller increases over time.</p> <p>Conclusions</p> <p>Some of the effects of HIV on growth were reversed with ART initiation, although a high proportion of children remained underweight and stunted after two years of treatment. Partnerships between treatment and nutrition programs should be explored so that HIV-infected children can receive optimal nutritional support.</p