The Dual Role of Ruthenium and Alkali Base Catalysts in Enabling a Conceptually New Shortcut to <i>N</i>‑Unsubstituted Pyrroles through Unmasked α‑Amino Aldehydes

A virtually salt-free and straightforward bimolecular assembly giving <i>N</i>-unsubstituted pyrroles through fully unmasked α-amino aldehydes, which was enabled by the dual effects of a catalytic ruthenium complex and an alkali metal base, is reported. Either solvent-free or acceptorless dehydrogenation facilitates high atom, step, and pot economy, which are otherwise difficult to achieve in multistep operations involving protection/deprotection

sj-jpg-4-jhs-10.1177_17531934221126864 - Supplemental material for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly

Supplemental material, sj-jpg-4-jhs-10.1177_17531934221126864 for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly by Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge and Naoki Morimoto in Journal of Hand Surgery (European Volume)</p

sj-jpg-2-jhs-10.1177_17531934221126864 - Supplemental material for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly

Supplemental material, sj-jpg-2-jhs-10.1177_17531934221126864 for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly by Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge and Naoki Morimoto in Journal of Hand Surgery (European Volume)</p

sj-jpg-1-jhs-10.1177_17531934221126864 - Supplemental material for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly

Supplemental material, sj-jpg-1-jhs-10.1177_17531934221126864 for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly by Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge and Naoki Morimoto in Journal of Hand Surgery (European Volume)</p

sj-jpg-3-jhs-10.1177_17531934221126864 - Supplemental material for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly

Supplemental material, sj-jpg-3-jhs-10.1177_17531934221126864 for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly by Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge and Naoki Morimoto in Journal of Hand Surgery (European Volume)</p

Diboron-Catalyzed Dehydrative Amidation of Aromatic Carboxylic Acids with Amines

Tetrakis­(dimethylamido)­diboron and tetrahydroxydiboron are herein reported as new catalysts for the synthesis of aryl amides by catalytic condensation of aromatic carboxylic acids with amines. The developed protocol is both simple and highly efficient over a broad range of substrates. This method thus represents an attractive approach for the use of diboron catalysts in the synthesis of amides without having to resort to stoichiometric or additional dehydrating agents

N‑Methylation of Amines with Methanol at Room Temperature

N-Methylation of amines with methanol proceeds at room temperature in the presence of a silver-loaded titanium dioxide (Ag/TiO₂) photocatalyst under UV–vis light irradiation. This method allows facile synthesis/isolation of <i>N</i>-methylamines bearing various functional groups including <i>N</i>-benzyl, <i>N</i>-allyl, <i>N</i>-Boc, hydroxyl, ether, acetal, carboxamide, formamide, and olefin groups