Co-sensitization graph of TLP allergens.

<p>Each node represents one allergen (TLP as white ellipses, non-TLP allergens as blue square nodes, and LTP-allergen Pru p 3 as a green diamond) and the links represent co-sensitization of one or more sera for the linked allergens. The weight of each link, ranging between 0 and 1, measures the degree of co-sensitization. For the sake of clarity, only the 25 links of weight greater than 0.50 out of the total 253 existing links were plotted.</p

Frequency of sensitization in the different geographical areas using the homemade microarray and sera from fruit-allergic (FAG) patients, and non-food pollen-allergic (PAG) subjects.

<p>Only TLPs with more than 10% positive response were represented: Pru p 2.0201, Pru p 2.0101, chestnut, plane, lettuce and cabbage TLPs.</p

Average weight of allergens included in the co-sensitization graph.

<p>Average weight of allergens included in the co-sensitization graph.</p

Pollen counts (grains/m³ of air) of the regions included in the study.

<p>Data were obtained as the average of the previous n years, from the Comité de Aerobiología-SEAIC (<a href="http://www.polenes.com/concentraciones.html" target="_blank">http://www.polenes.com/concentraciones.html</a>) and from PIA-Punto de información de Aerobiología-UAB (<a href="http://lap.uab.cat/aerobiologia/" target="_blank">http://lap.uab.cat/aerobiologia/</a>).</p>*<p>Average of pollen counts (grains/m³). The time period is indicated in brackets.</p

Characteristics of the patient sample.

1<p>Total, all patients;</p>2<p>FAG, Fruit-allergic patients;</p>3<p>PAG, Pollen-allergic food-tolerant patients;</p>4<p>M, male; F, female;</p>*<p>SPTs with purified protein were performed in a selected group of patients of 50 FAG, 20 PAG and 20 non-pollen food-tolerant subjects.</p

Frequency of sensitization obtained by the TLP microarray using sera from both fruit-allergic (FAG) patients, and non-food pollen allergic (PAG) subjects.

<p>Odds ratios are presented in parentheses (95% CI; <i>p</i><0.001).</p

IgE binding inhibition of the TLP microarray, when serum pool (n = 21; three per area) or individual sera were preincubated for 3 h at room temperature with increasing amounts of Pru p 2.0201, and chestnut and plane -pollen TLPs.

<p>IgE binding inhibition of the TLP microarray, when serum pool (n = 21; three per area) or individual sera were preincubated for 3 h at room temperature with increasing amounts of Pru p 2.0201, and chestnut and plane -pollen TLPs.</p