Pelatihan Training Circles 15 Repetisi 4 Set dan 10 Repetisi 6 Set terhadap Peningkatan Kekuatan Otot Perut Siswa Putri Kelas VIII SMP Negeri 2 Kuta Tahun Pelajaran 2017/2018

Berdasarkan pengamatan, prestasi cabang olahraga atletik maupun permainan sampai saat ini masih belum mampu menunjukkan hasil yang optimal hal ini karena siswa kurangnya mendapat pelatihan otot Perut, kurang menguasai teknik latihan otot Perut serta kurangnya minat dalam melatih otot Perut. Populasi dalam penelitian ini adalah siswa putri kelas VIII SMP Negeri 2 Kuta berjumlah 58 orang dan seluruhnya digunakan sebagai sempel dengan teknik populasi study yang meneliti seluruh subjek penelititan. Alat ukur yang digunakan adalah tes perbuatan dengan melakukan baring duduk (sit-up) selama 30 detik. Analisis data yang dipergunakan adalah metode analisis statistic dengan rumus t-tes. Berdasarkan analisis data diperoleh t-tes kelompok eksperimen I sebesar 5,742 sedangkan t-tabel didapat sebesar 2,048 dengan taraf signifikansi 5% dandb = 28. Demikian juga pada kelompok eksperimen II diperoleh t-tes sebesar 7,061 sedangkan t-tabel didapat sebesar 2,048 dengan taraf signifikansi 5% dandb = 28. Perbedaan kelompok eksperimen I dan II di peroleh t-tes sebesar 1,318 sedangkan t-tabel didapat sebesar 2,000 dengan taraf signifikansi 5% dan db = 56. Berdasarkan hasil penelitian ini, dapat disimpulkan  bahwa eksperimen pertama dan eksperimen kedua sama-sama mempunyai pengaruh yang signifikan terhadap peningkatan kekuatan otot Perut siswa putrid kelas VIII SMP Negeri 2 Kuta. Sehingga eksperimen pertama dan eksperimen kedua, hipotesis nol ditolak dan hipotesis alternative diterima. Untuk perbedaan pengaruh eksperimen pertama dan eksperimen kedua, hipotesis nol diterima dan hipotesis alternative ditolak. Karena kedua bentuk pelatihan tidak ada perbedaan pengaruh yang signifikan maka aplikasi di lapangan dapat dipergunakan salah satu atau kedua bentuk pelatihan training circles 15 repetisi 4 set dan 10 repetisi 6 set terhadap peningkatan kekuatan otot Perut siswa putrid kelas VIII SMP Negeri 2 Kuta

Restrictions on the Material Coefficients in the Constitutive Theories for Non-Classical Viscous Fluent Continua

This paper considers conservation and balance laws and the constitutive theo-ries for non-classical viscous fluent continua without memory, in which in-ternal rotation rates due to the velocity gradient tensor are incorporated in the thermodynamic framework. The constitutive theories for the deviatoric part of the symmetric Cauchy stress tensor and the Cauchy moment tensor are de-rived based on integrity. The constitutive theories for the Cauchy moment tensor are considered when the balance of moments of moments 1) is not a balance law and 2) is a balance law. The constitutive theory for heat vector based on integrity is also considered. Restrictions on the material coefficients in the constitutive theories for the stress tensor, moment tensor, and heat vector are established using the conditions resulting from the entropy inequa-lity, keeping in mind that the constitutive theories derived here based on inte-grity are in fact nonlinear constitutive theories. It is shown that in the case of the simplest linear constitutive theory for stress tensor used predominantly for compressible viscous fluids, Stokes’ hypothesis or Stokes’ assumption has no thermodynamic basis, hence may be viewed incorrect. Thermodynamically consistent derivations of the restrictions on various material coefficients are presented for non-classical as well as classical theories that are applicable to nonlinear constitutive theories, which are inevitable if the constitutive theo-ries are derived based on integrity

COMBINATION OF MOMORDICA CHARANTIA AND PHYLLANTHUS AMARUS FOR HEPATOPROTECTIVE ACTIVITY IN ETHANOL AND ANTI-TUBERCULAR DRUGS INDUCED HEPATOTOXICITY IN RATS

Objective: To evaluate the synergistic protective effect of Momordica charantia and Phyllanthus amarus combination (MC+PA) of doses 200 and 400 mg/kg on the liver in different experimental models of hepatotoxicity. Methods: The hepatoprotective activity was evaluated in ethanol and anti-tubercular drugs (isoniazid-INH, rifampicin-RIF) induced hepatotoxicity models. Hepatotoxicity in both models was induced to all groups except the normal control. Intoxicated rats were treated with silymarin and various doses of MC+PA for 8 d in ethanol-induced and 21 d in INH+RIF induced hepatotoxicity models. At the completion of study, the biochemical markers and the anti-oxidant status (SOD and MDA) were measured and also the histopathological evaluation of the liver tissue was carried out. Results: Combination therapy remarkably reduced the elevated profile of the biochemical markers and thereby improved the anti-oxidant status, thus exhibiting the synergistic hepatoprotective effect when compared with the positive control group (p<0.001). Histopathological evaluation demonstrated that MC+PA decreased the liver damage significantly in comparison with the positive group. Conclusion: The current work suggests that the combined extract showed synergistic effects on ethanol and anti-tubercular drugs induced hepatotoxicity models by significantly decreasing the liver damage

Role of Murine Intestinal Interleukin-1 Receptor 1-Expressing Lymphoid Tissue Inducer-Like Cells in Salmonella Infection

Interleukin (IL)-1 signaling plays a critical role in intestinal immunology. Here, we report that the major population of intestinal lamina propria lymphocytes expressing IL-1 receptor 1 (IL-1R1) is the lymphoid tissue inducer (LTi)-like cell, a type of innate lymphoid cell. These cells are significant producers of IL-22, and this IL-22 production depends on IL-1R1 signaling. LTi-like cells are required for defense against Salmonella enterica serovar Typhimurium. Moreover, colonic LTi-like cell numbers depend on the presence of the intestinal microbiota. LTi-like cells require IL-1R1 for production of protective cytokines and confer protection in infectious colitis, and their cell numbers in the colon depend upon having a microbiome

Sutterella and its metabolic pathways positively correlate with vaccine-elicited antibody responses in infant rhesus macaques

IntroductionIt is becoming clearer that the microbiota helps drive responses to vaccines; however, little is known about the underlying mechanism. In this study, we aimed to identify microbial features that are associated with vaccine immunogenicity in infant rhesus macaques.MethodsWe analyzed 16S rRNA gene sequencing data of 215 fecal samples collected at multiple timepoints from 64 nursery-reared infant macaques that received various HIV vaccine regimens. PERMANOVA tests were performed to determine factors affecting composition of the gut microbiota throughout the first eight months of life in these monkeys. We used DESeq2 to identify differentially abundant bacterial taxa, PICRUSt2 to impute metagenomic information, and mass spectrophotometry to determine levels of fecal short-chain fatty acids and bile acids.ResultsComposition of the early-life gut microbial communities in nursery-reared rhesus macaques from the same animal care facility was driven by age, birth year, and vaccination status. We identified a Sutterella and a Rodentibacter species that positively correlated with vaccine-elicited antibody responses, with the Sutterella species exhibiting more robust findings. Analysis of Sutterella-related metagenomic data revealed five metabolic pathways that significantly correlated with improved antibody responses following HIV vaccination. Given these pathways have been associated with short-chain fatty acids and bile acids, we quantified the fecal concentration of these metabolites and found several that correlated with higher levels of HIV immunogen-elicited plasma IgG.DiscussionOur findings highlight an intricate bidirectional relationship between the microbiota and vaccines, where multiple aspects of the vaccination regimen modulate the microbiota and specific microbial features facilitate vaccine responses. An improved understanding of this microbiota–vaccine interplay will help develop more effective vaccines, particularly those that are tailored for early life

Ascorbic Acid is an Abettor in Calcium Urolithiasis: An Experimental Study

Two sets of animal experiments using guinea pigs were planned to evaluate the effect of ascorbic acid supplementation on the lithogenic process. In the first set of experiments, 10, 40, and 60 mg doses of ascorbic acid/100g body weight/day were given for 105 days. Neither of the ascorbic acid doses given induced crystalluria, calcification or stone formation, thereby confirming our previous findings that ascorbic acid in the doses used by clinicians does not cause urolith formation. In the second set of experiments, ascorbic acid was supplemented in hypercalciuric (induced by calcium carbonate feeding) and hyperoxaluric (induced by sodium oxalate feeding) animals for 45 days. The results indicated that it exacerbated the calcification process in renal and bladder tissue

Sferic propagation in the cutoff region of the earth-ionosphere waveguide

Thesis (M. Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.Includes bibliographical references (leaves 93-96).The waveguide cutoff phenomenon provides information about the height of a waveguide. This cutoff for the earth-ionosphere waveguide is illuminated by lightning sferics and is used to monitor the change in ionosphere height through the day-night boundary. The observed ionospheric heights are found to be dependent on the three kinds of source-receiver paths: daytime, nighttime and mixed. Accurate locations for individual events are obtained from the National Lightning Detection Network (NLDN) to enable the analysis. Tweek sferics, which asymptote towards the transverse resonance frequency of the waveguide, predominate in the night path giving the most precise information about ionospheric heights. Weak dispersion and steep transitions in one-dimensional spectra provide information about daytime heights. Propagation over mixed paths reveals both daytime and nighttime signatures. Nighttime observations are also compared against theoretical predictions (Porrat et al, 2001). Agreement is best for large peak current events ( > 100) kA). Some indication of a residual daytime effect in a nighttime ionosphere is also observed.by Kunal K. Surana.M.Eng.and S.B

Synthesizing non-natural parts from natural genomic template

<p>Abstract</p> <p>Background</p> <p>The current knowledge of genes and proteins comes from 'naturally designed' coding and non-coding regions. It would be interesting to move beyond natural boundaries and make user-defined parts. To explore this possibility we made six non-natural proteins in <it>E. coli</it>. We also studied their potential tertiary structure and phenotypic outcomes.</p> <p>Results</p> <p>The chosen intergenic sequences were amplified and expressed using pBAD 202/D-TOPO vector. All six proteins showed significantly low similarity to the known proteins in the NCBI protein database. The protein expression was confirmed through Western blot. The endogenous expression of one of the proteins resulted in the cell growth inhibition. The growth inhibition was completely rescued by culturing cells in the inducer-free medium. Computational structure prediction suggests globular tertiary structure for two of the six non-natural proteins synthesized.</p> <p>Conclusion</p> <p>To our best knowledge, this is the first study that demonstrates artificial synthesis of non-natural proteins from existing genomic template, their potential tertiary structure and phenotypic outcome. The work presented in this paper opens up a new avenue of investigating fundamental biology. Our approach can also be used to synthesize large numbers of non-natural RNA and protein parts for useful applications.</p

Si nanoparticle interfaces in Si/SiO2 solar cell materials

Novel solar cell materials consisting of Si nanoparticles embedded in SiO2 layers have been studied using positron annihilation spectroscopy in Doppler broadening mode and photoluminescence. Two positron-trapping interface states are observed after high temperature annealing at 1100 °C. One of the states is attributed to the (SiO2/Si bulk) interface and the other to the interface between the Si nanoparticles and SiO2. A small reduction in positron trapping into these states is observed after annealing the samples in N2 atmosphere with 5% H2. Enhanced photoluminescence is also observed from the samples following this annealing step.Peer reviewe