Formulasi Sirup Analgesik Ekstrak Etanol Daun Songgolangit (Tridax procumbens L.)

ABSTRACTThe aims of this research were to testing the quality of songgolangit leaves ethanol extractanalgesic syrup. Songgolangit leaves ethanol extract analgesic syrup were make with 3various concentrations of active substances which are 40%, 50%, 60% and the quality weretesting. The outcome of quality testing of songgolangit leaves ethanol extract syrup has agood homogeneity. On organoleptic test, songgolangit leaves ethanol extract syrup wassmelling like extract, has a bitter taste, and colored yellow. The pH of songgolangit leavesethanol extract syrup be on the maximum stability which are on 5-7 pH. The average ofcastings time be on the similliar values with the positif control that become a parameter.Key words : analgesic, Tridax procumbens L

FORMULASI KRIM TABIR SURYA EKSTRAK KULIT NANAS (ANANAS COMOSUS L MERR) DAN UJI IN VITRO NILAI SUN PROTECTING FACTOR (SPF)

This research aims to determine the value of sun protecting factor (SPF) of pineapple skinextracts (Ananas comosus L Merr) in the form of cream with variant concentration of 2%,4% and 8%. The pineapple skin contains flavonoids and tannins substances that can give theeffect as a sunscreen. The formulation of pineapple skin extract cream using the phase of oilin water. The ingredients that was use in the cream formulation are stearic acid, liquidparaffin cera alba, cetyl alcohol, stearyl alcohol, propylene glycol, triethanolamine, distilledwater and nipagin. Cream of pineapple skin extract then giving a variety of specified qualitytesting and SPF value. Each concentration cream diluted using 96% ethanol. Creams that hasbeen diluted read it’s absorbance value at UV-Vis Spectrophotometer instrument thencalculated the SPF values. The results showed that the cream of pineapple skin extract hasmet the requirements after conducting various quality of cream tests and the SPF value ofeach cream concentrations are very low. It’s been Concluded that the concentration ofpineapple skin extract cream 2% has shown a very small SPF value and increasing theconcentration of 4% and 8% demonstrate higher SPF values but still does not meet thestandards as a good sunscreen cream.Keywords : cream, extract, pineapple skin, sunscreen, sun protecting facto

EFEK ANTIBAKTERI SALEP EKSTRAK RIMPANG LENGKUAS PUTIH (Alpinia galangal [L] Swartz) PADA KULIT PUNGGUNG KELINCI YANG DIBUAT INFEKSI Staphylococcus aureus

The aim of these research were to study antibacterial effect, effective concentration, and theeffect of concentration alteration of white galangal rhizome extract ointmentto heal rabbitsback skininfected with Staphylococcus aureus. Extraction was done by maceration usingethanol 96% as solvent. Observation of healing time was done by observing infectionhealingtime on rabbits back skin after anointment treatment, which based onthe disappearance oferythema and pus. The result shows that 10% of white galangal rhizome extract ointmenteffective to heal the infection of Staphylococcus aureus. It shown by its short healing timecompared with concentration 3% and 5%. One way ANOVA result shows that there was asignificant effect between concentrations 3%, 5%,and 10%. (Fcalculation 27,30>Ftable 3,48),it meant that high concentration resultingshorter healing time.Keywords: antibacterial effect. Alpinia galangal L., Staphylococcus aureus, rabbit backski

Uji Efektivitas Eksrak Kulit Pisang Goroho (Musa Acuminate L.) Terhadap Penurunan Kadar Glukosa Darah pada Tikus Putih Jantan Galur Wistar yang diinduksi Sukrosa

ABSTRACT The objectives of this research were to study the effect of Goroho banana (Musa Acuminate L.) peel extract on the decreasing of blood glucose content  of white male wistar induced with sucrose. This research using Randomized Controlled Group Design .The subjects in these research were 15 mices which divided into 3 groups, namely negative control (aquadest),  treatments groupusing Goroho banana peel extract 0,03 g/KgBB, and positive control using metformin 45 mg/KgBB. Data were obtained from fasting blood glucose examination, 30 minutes after induced with sucrose, and at 15, 30, 60, and 120 minutes treatment. Data analyzed statistically using ANOVA (Analysis Of Variant), the results extract goroho banan peel provide an effect on blood glucose content. LSD (Least Significant Different) domonstrate distinct difference, significant effect between negative group with treatment, negative group with positive group, but did not show differences between treatment group with positive group. Is Goroho banana peel extract exhibit activity to decrease blood glucose content of white male wistar induced with sucrose. Keywords: Musa acuminate L. goroho banana peel, blood glucose content, sucros

FORMULASI KRIM PENYEMBUH LUKA TERINFEKSI Staphylococcus aureus EKSTRAK DAUN TAPAK KUDA (Ipomoea pes-caprae (L.) Sweet PADA TIPE A/M

ABSTRACTBeach Morning Glory is a plant that grew around the beach which has purple flower. BeachMorning Glory leaves contains chemical compounds such Flavonoids, Hydroquinonephenolic, alkaloids, and Tannins. Beach Morning Glory leaves has known as the medicine ofacne and furunkulosis that caused by Staphylococcus aureus. The topical product is needed toheal the skin infection. The purpose of this research were to test about physical quality ofcream based and Beach Morning Glory cream extract at the concentration between 2,5 %, 5%, and 7,5%. The result shows the cream base and Beach Morning Glory cream withconcentration of 2,5 %, 5 %, and 7,5 % fulfilled the Organoleptic and Homogenity test butwas not fulfilled in the standart parameter of pH and spreadabillity.Keywords : Ipomoea pes-caprae (L.) Sweet, W/O Cream

FORMULASI SEDIAAN GRANUL EFFERVESCENT SARI BUAH SIRSAK (Annona muricata L)

Soursoup fruit nutrient includes vitamins C and B1. Vitamin which is the most dominant insoursop fruit is vitaman C, where the compound is in the form of a natural antioxidant in thebody. Antioxidants help the body to fight against various free radicals that enter the body and isexcellent for improving the immune system and slow the aging process. This study aimed toinvestigate the effect of different formulations of effervescent granules made from soursoup fruitjuice against physical properties of granules prepared by wet granulation method. Testpreparation includes organoleptic quality, moisture content, flow properties, and solubility time.Of the three formulations, variations in the quantity of citric acid, tartaric acid and sodiumbicarbonate gave effect on water levels, silence angle, and time of depression of granule made ofsoursoup fruit juice. In formulation 1, the water content was 0.19%, a flow rate of 8.2 seconds,the silence angle of 33.02 degrees, and dispersion time was 2 minutes 13 seconds.In the secondformulation, water content was 0,21%, a flow rate of 8.1 seconds, the silence angle of 31.52degrees, and dispersion time at 3 minutes 3 seconds. In the third formulation, water content was0,28%, a flow rate of 9,7 seconds, the silence angle of 31.56 degrees, and dispersion time at 4minutes 5 seconds.Key words: soursoup, effervescent granule, wet granule, natrium bicarbonat