4 research outputs found
Persistent primitive hypoglossal artery associated with lower basilar artery aneurysm: Diagnosis and clinical implications
Unusual clinical and radiological presentation of metastatic choriocarcinoma to the brain and long-term remission following emergency craniotomy and adjuvant EMA-CO chemotherapy
Choriocarcinoma is the most malignant tumor of gestational trophoblast
origin. Metastasis to brain is considered a poor prognostic indicator.
Recent advances in adjuvant radiotherapy and chemotherapy have led to
an excellent outcome of these patients. Craniotomy is indicated in
selected cases with cerebral metastases. The authors report an
interesting case of an aggressive choriocarcinoma with multiple
metastases to the brain and viscera. The patient had radiological
evidence of new lesions occurring almost every week while on the
initial treatment and yet had a complete long-term remission with
EMA-CO therapy. The interesting presentation, radiology and adjuvant
therapies are discussed
Coexisting intracranial tumors with pituitary adenomas: Genetic association or coincidence?
The co-occurrence of two or more brain tumors with different
histological features is rare. The authors report three rare cases of
intracranial tumors associated with pituitary adenomas. Two of the
pituitary tumors were functioning adenomas: a prolactinoma and a
thyrotropin secreting adenoma. Two of the associated intracranial
neoplasms were gliomas and one was a meningioma. Radiological and
clinical examination for syndromal association was negative in all
cases. We briefly discuss the presentation and treatment options of
these cases and review the 19 previous publications in the literature
of pituitary tumors occurring in association with other neoplasms and
explore the possible links underlying these co-occurring neoplasms. Our
three cases represent 0.86% of all pituitary tumors operated at our
institute over a 9-year period