MOESM5 of Time series analysis of malaria in Afghanistan: using ARIMA models to predict future trends in incidence

Additional file 2. Area-Averaged of CMG 0.05 Deg Monthly EVI monthly 0.05 ()

MOESM2 of Time series analysis of malaria in Afghanistan: using ARIMA models to predict future trends in incidence

Additional file 5. Area-Averaged of Relative Humidity at Surface (Daytime/Ascending) ()

Predictions related to trough and peak capillary plasma concentration of PQ at steady-state with various chemoprevention regimens of DP in 1–2 year olds weighing ≥ 11 kg.

<p>Predictions related to trough and peak capillary plasma concentration of PQ at steady-state with various chemoprevention regimens of DP in 1–2 year olds weighing ≥ 11 kg.</p

Comparative predicted capillary plasma PQ concentrations with and without a loading dose of DP and predicted maximum concentration with a loading dose of DP in 1–2 year olds weighing ≥ 11 kg.

<p>Comparative predicted capillary plasma PQ concentrations with and without a loading dose of DP and predicted maximum concentration with a loading dose of DP in 1–2 year olds weighing ≥ 11 kg.</p

DP weight-based dosing guidelines.

<p>DP weight-based dosing guidelines.</p

Association of predictor variables with the incidence of malaria.

<p><b>NOTE</b> RR, relative risk.</p>a<p>Previously published results from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007246#pone-0007246-t001" target="_blank">Table 1</a><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007246#pone.0007246-Clark1" target="_blank">[8]</a>, showing results of regression analysis using G6PD deficiency defined by enzyme assay.</p>b<p>Repeat regression analysis using G6PD deficiency defined by genotype. Note that RR for other covariates remain constant.</p

Dot plot showing the distribution of G6PD enzyme activity stratified by genotype.

<p>Dot plot showing the distribution of G6PD enzyme activity stratified by genotype.</p

Correlation of Phenotype with Genotype by Gender.

<p>Correlation of Phenotype with Genotype by Gender.</p

Effect of G6PD activity cut-off criteria on the association analysis of G6PD status and malaria incidence.

<p>NOTE: N, represents the total number of individuals who have a G6PD activity level below the specified cut-off point; RR, relative risk.</p><p>NOTE: Table depicts how the relative risk of malaria varies depending on the cut-off point for determining G6PD deficiency by enzymatic assay.</p>*<p>Sample sizes are too small for meaningful analysis of enzymatically deficient females in these categories.</p

Distribution of G6PD enzyme activity (mU/10⁹ erythrocytes) in all individuals, males, and females.

<p>For the male and female distributions, G6PD A- genotype data are also displayed, with wild-type individuals represented by a dark gray bar and hemizygous, heterozygous, and homozygous individuals by a light gray bar.</p