29 research outputs found

    Clinical effectiveness of the sequential 4-channel NMES compared with that of the conventional 2-channel NMES for the treatment of dysphagia in a prospective double-blind randomized controlled study

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    Background To date, conventional swallowing therapies and 2-channel neuromuscular electrical stimulation (NMES) are standard treatments for dysphagia. The precise mechanism of 2-channel NMES treatment has not been determined, and there are controversies regarding the efficacy of this therapy. The sequential 4-channel NMES was recently developed and its action is based on the normal contractile sequence of swallowing-related muscles. Objective To evaluate and compare the rehabilitative effectiveness of the sequential 4-channel NMES with that of conventional 2-channel NMES. Methods In this prospective randomized case–control study, 26 subjects with dysphagia were enrolled. All participants received 2- or 4-channel NMES for 2–3weeks (minimal session: 7 times, treatment duration: 300–800min). Twelve subjects in the 4-channel NMES group and eleven subjects in the 2-channel NMES group completed the intervention. Initial and follow-up evaluations were performed using the videofluoroscopic dysphagia scale (VDS), the penetration-aspiration scale (PAS), the MD Anderson dysphagia inventory (MDADI), the functional oral intake scale (FOIS), and the Likert scale. Results The sequential 4-channel NMES group experienced significant improvement in their VDS (oral, pharyngeal, and total), PAS, FOIS, and MDADI (emotional, functional, and physical subsets) scores, based on their pretreatment data. VDS (oral, pharyngeal, and total) and MDADI (emotional and physical subsets) scores, but not PAS and FOIS scores, significantly improved in the 2-channel NMES group posttreatment. When the two groups were directly compared, the 4-channel NMES group showed significant improvement in oral and total VDS scores. Conclusions The sequential 4-channel NMES, through its activation of the suprahyoid and thyrohyoid muscles, and other infrahyoid muscles mimicking physiological activation, may be a new effective treatment for dysphagia. Trial registration: clinicaltrial.gov, registration number: NCT03670498, registered 13 September 2018, https://clinicaltrials.gov/ct2/show/NCT03670498?term=NCT03670498&draw=2&rank=1 .This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (Grant Number: HI18C1169). This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Min‑ istry of Science, ICT and Future Planning (NRF- NRF-2016R1D1A1B03935130)

    Dental Adhesion Enhancement On Zirconia Inspired By Mussel\u27S Priming Strategy Using Catechol

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    Zirconia has recently become one of the most popular dental materials in prosthodontics being used in crowns, bridges, and implants. However, weak bonding strength of dental adhesives and resins to zirconia surface has been a grand challenge in dentistry, thus finding a better adhesion to zirconia is urgently required. Marine sessile organisms such as mussels use a unique priming strategy to produce a strong bonding to wet mineral surfaces; one of the distinctive chemical features in the mussel\u27s adhesive primer proteins is high catechol contents among others. In this study, we pursued a bioinspired adhesion strategy, using a synthetic catechol primer applied to dental zirconia surfaces to study the effect of catecholic priming to shear bond strength. Catechol priming provided a statistically significant enhancement (p \u3c 0.05) in shear bond strength compared to the bonding strength without priming, and relatively stronger bonding than commercially available zirconia priming techniques. This new bioinspired dental priming approach can be an excellent addition to the practitioner\u27s toolkit to improve dental bonding to zirconia

    Dental Adhesion Enhancement on Zirconia Inspired by Mussel’s Priming Strategy Using Catechol

    No full text
    Zirconia has recently become one of the most popular dental materials in prosthodontics being used in crowns, bridges, and implants. However, weak bonding strength of dental adhesives and resins to zirconia surface has been a grand challenge in dentistry, thus finding a better adhesion to zirconia is urgently required. Marine sessile organisms such as mussels use a unique priming strategy to produce a strong bonding to wet mineral surfaces; one of the distinctive chemical features in the mussel’s adhesive primer proteins is high catechol contents among others. In this study, we pursued a bioinspired adhesion strategy, using a synthetic catechol primer applied to dental zirconia surfaces to study the effect of catecholic priming to shear bond strength. Catechol priming provided a statistically significant enhancement (p < 0.05) in shear bond strength compared to the bonding strength without priming, and relatively stronger bonding than commercially available zirconia priming techniques. This new bioinspired dental priming approach can be an excellent addition to the practitioner’s toolkit to improve dental bonding to zirconia

    The Stability of Temporary Restorations Fabricated on a Healing Cap for Immediate Loading: An In Vitro Study

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    The aim of this study was to analyze the load distribution of interim restorations using healing cap during immediate loading implant treatment in vitro. A total of 29 models with interim restorations which were fabricated with healing cap were selected. The pull-out strength was measured with a used healing cap and new healing cap. The compressive strength and sinking distance were also measured. The pull-out strength of interim restoration showed lower value (max. 29.8 N) compared to the natural bite force. The sinking amounts were larger than normal tooth sinking. The sinking amounts of interim restorations fabricated on a healing cap were roughly 3 times (0.3⁻0.5 mm under 450 N) those of normal teeth. The interim restoration on plastic healing cap would be useful for immediate loading implant treatment

    Direct Measurement of Heat Produced during Drilling for Implant Site Preparation

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    The aim of this study was to directly measure the temperature of the drill during implant site preparation. The measured temperature was compared to that previously reported inside the bone. The temperature change of the drill was measured using a thermocouple inserted inside the stainless steel drill using an 18-gauge needle and mercury-containing slip ring. Three thermocouples were inserted into the bone with different depths of 10 mm, 5 mm and 1 mm. The thermocouple was 0.5 mm away from the periphery of the drilled hole with a diameter of 3.4 mm. The drill rotating speed varied from 500 rpm to 2000 rpm. Each drilling procedure was performed 10 times, and the average was calculated. The temperature of the drill increased rapidly, and the thermocouples in the bone reached a maximum temperature after the drill temperature started to decrease. The maximum inner temperature of the bone was the highest at a depth of 10 mm. The patterns of the temperature change were similar at different rotating speeds. The actual maximum temperature at the drill and bone interface was significantly higher than the temperature measured inside the bone in previous reports

    Thermodynamic and Spectroscopic Identification of Guest Gas Enclathration in the Double Tetra-n-butylammonium Fluoride Semiclathrates

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    The precise nature and unique pattern of the double tetra-n-butylammonium fluoride (TBAF) semiclathrates with a guest gas (CH4 or CO2) was closely investigated through thermodynamic and spectroscopic analyses. The three-phase equilibria of semiclathrate (H), liquid water (L-w), and vapor (V) for the ternary CH4 + TBAF + water and CO2 + TBAF + water mixtures with various TBAF concentrations were experimentally measured in order to determine the stability conditions of the double TBAF semiclathrates. The double CH4 (or CO2) + TBAF semiclathrates showed remarkably enhanced thermal stability when compared with pure CH4 (or CO2) hydrate. The highest stabilization effect was observed at the stoichiometric concentration of pure TBAF semiclathrate, which is 3.3 mol %. Gas uptake measurements were undertaken in order to estimate the amount of gas consumed during double semiclathrate formation. CH4 was found to be a relatively more favorable guest for the 5(12) cages of the double TBAF semiclathrate than CO2. From the results of the NMR and Raman spectroscopic analyses it was identified that the guest gas molecules (CH4 or CO2) were enclathrated in the 5(12) cages of the double TBAF semiclathrates. The overall results given in this study are useful for understanding the fundamental guest gas enclathration behavior in the double semiclathrates.close
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