1 research outputs found
On-Surface Azide–Alkyne Cycloaddition on Cu(111): Does It “Click” in Ultrahigh Vacuum?
Using scanning tunneling microscopy, we demonstrate that
the 1,3-dipolar
cycloaddition between a terminal alkyne and an azide can be performed
under solvent-free ultrahigh vacuum conditions with reactants adsorbed
on a Cu(111) surface. XPS shows significant degradation of the azide
upon adsorption, which is found to be the limiting factor for the
reaction