86 research outputs found

    A Gravity Model Integrating Land-Use and Transportation Policies for Sustainable Development: Case Study of Fresno, California

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    ZSB12017-SJAUXCA-MTI-2222The idea of urban compaction has been long proposed and promoted to address the problem of urban sprawl in many American cities. However, successful cases of implementation in this regard are still rare in the United States. This study uses a classic gravity model, TELUM (Transportation, Economic, and Land-Use Model) to examine the extent to which a land-use or transportation policy must be regulated to make the urban compaction occur in a typical auto-dependent city\u2014Fresno, California. Five scenarios are considered (BL, L1, L2, T1, and T2), in which the baseline (BL) is a natural growth scenario. Without any policy interventions, the city will inevitably expand outward. The L1 (high-intensity zoning) and L2 (growth boundary) results suggest that high-density zoning and growth boundary policies could enable the compaction. The T1 (location impedance) and T2 (carbon tax) results reveal that transportation interventions would create barriers among regions/areas and therefore should be carefully used for compaction. This study not only adds to the literature on urban modeling but also contributes to the practice of smart growth or new urbanism policies for sustainability

    Complexome of Escherichia coli cytosolic proteins under normal native conditions

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    The interactions between proteins are important for the majority of biological functions and the interacting proteins are usually assembled into a complex. Knowing a set of protein complexes of a cell (complexome) is, therefore, essential for a better understanding and global view of cell functions. To visualize and identify the protein complexome of E. coli K-12 under normal native conditions on a proteome-wide scale, we developed an integrated proteomic platform with the combination of 2-D native/SDS-PAGE-based proteomics with co-immunoprecipitation, far-Western blotting, His-tag affinity purification and functional analysis, and used it to investigate the E. coli cytosolic complexome. A total of 24 distinct heteromeric and 8 homomeric protein complexes were identified. These complexes mainly contributed to glycolysis/gluconeogenesis, bioinformation processing, and cellular processes. Of the 24 hetereomeric complexes, 16 were reported for the first time, and 2 known complexes contained novel components that have not been reported previously based on DIP database search. Among them, RpoC-RpsA-Tig-GroL was found to be involved in transcriptional and co-translational folding, and EF-G-TufA-Tsf-RpsA linked a protein synthesis site with protein translational elongation factors. This systematic proteome analysis provides new insights into E. coli molecular systems biology.NSFC[30972279, 40976080]; Sun Yat-sen University[10lgzd03, SKLBC09B04

    CCDC 1914282: Experimental Crystal Structure Determination

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    Related Article: zhang yu|2019|CSD Communication|||,Related Article: Yu Zhang, Zhe Chang, Heng Zhao, Stefano Crespi, Ben L. Feringa, Depeng Zhao|2020|Cell Press: Chem|6|2420|doi:10.1016/j.chempr.2020.07.025

    The influence of service environment and brand equity on gaming customer engagement

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    To date, customer engagement research has primarily focused on individual behaviors, while impacts of organizational attributes on customer engagement and its consequences have not received equal attention. The study fills the literature gap by proposing a chain relationship of service environment, customer engagement, impulsive behavior, and customer loyalty in the casino context. Casino service environment and brand equity are conceptualized as an organizational level of constructs to exert cross-level moderating effects on this relationship chain in order to gain insights into gambling behaviours. Two independent surveys were undertaken to examine the proposed cross-level relationships. Results show that casino service environment has significant direct and moderating effects on customer engagement. Impulsive gambling behavior can be driven by customer engagement and prompted by the service environment. Whilst casino brand equity does exert significant moderating effects, only certain loyalty behaviors can be enhanced by the casino brand. The findings not only point to a significant mediating role of impulsive behavior on the customer engagement-loyalty relationship, but also show an indirect effect on both attitudinal and behavioral loyalty manifested in revisit intention, positive WOM, willingness to pay more, actual spending, and frequency of visit

    CCDC 1914274: Experimental Crystal Structure Determination

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    Related Article: zhang yu|2019|CSD Communication|||,Related Article: Yu Zhang, Zhe Chang, Heng Zhao, Stefano Crespi, Ben L. Feringa, Depeng Zhao|2020|Cell Press: Chem|6|2420|doi:10.1016/j.chempr.2020.07.025

    CCDC 1914275: Experimental Crystal Structure Determination

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    Related Article: zhang yu|2019|CSD Communication|||,Related Article: Yu Zhang, Zhe Chang, Heng Zhao, Stefano Crespi, Ben L. Feringa, Depeng Zhao|2020|Cell Press: Chem|6|2420|doi:10.1016/j.chempr.2020.07.025

    A materials genome approach for heterogeneous integration [Abstract]

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    As heterogeneous integration and orthogonal scaling gradually dominate the semiconductor industry ecosystem, a holistic approach of co-designing materials, process, chip and system interactions is required. In particular, materials used in the heterogeneous integration are approaching their physical limits. As such current and new materials are key to the development of new devices and disruptive technologies. The myriad of materials spanning multiple scales and the inherent multiscale microstructures of materials ultimately control the properties of components and thence the performance of devices. In the orthogonal scaling era, material and microstructural parameters at scales ranging from an electronic and atomistic/molecular scale up to a meso-scale become significant and drives the continuation of the orthogonal scaling. A co-design platform for heterogeneous integration requires a transition from computer-aided new material design to novel simulation and virtual integration during product development. In such a scenario, key material parameters with respect to interfaces, dispersion of nano-material constituents, porosity, and hierarchical microstructural information need to be quantified in the first instance, followed by establishing linkages among materials, process and device performance using deep learning algorithms. Such hierarchical microstructural informatics, or the so called “materials genome”, is currently lacking but needs to be accessible and fully incorporated into the co-design platform for new future devices. This paper outlines the necessity of the materials genome approach for heterogeneous integration and reviews the building blocks and recent progress towards this direction in light of the accomplishments of the US Materials Genome Initiative (MGI) in the first five years

    CCDC 2170186: Experimental Crystal Structure Determination

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    An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures
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