4,504 research outputs found

    NLO QCD corrections to Single Top and W associated production at the LHC with forward detector acceptances

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    In this paper we study the Single Top and W boson associated photoproduction via the main reaction pppγppW±t+Y\rm pp\rightarrow p\gamma p\rightarrow pW^{\pm}t+Y at the 14 TeV Large Hadron Collider (LHC) up to next-to-leading order (NLO) QCD level assuming a typical LHC multipurpose forward detector. We use the Five-Flavor-Number Schemes (5FNS) with massless bottom quark assumption in the whole calculation. Our results show that the QCD NLO corrections can reduce the scale uncertainty. The typical K-factors are in the range of 1.15 to 1.2 which lead to the QCD NLO corrections of 15% to 20% correspond to the leading-order (LO) predictions with our chosen parameters.Comment: 41pages, 12figures. arXiv admin note: text overlap with arXiv:1106.2890 by other author

    CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase

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    One of the hallmarks of osteoarthritic cartilage is the loss of chondrocyte cellularity due to cell death. However, considerable controversy has recently arisen surrounding the extent of apoptotic cell death involved in development of osteoarthritis (OA). To shed light on this issue, we characterized cell death in primary OA chondrocytes mediated by the CD95 (Fas) pathway. Treatment of chondrocytes with anti-CD95 not only increased the rate of cell death but also increased the production of CD95 ligand by chondrocytes. This reveals a novel autocrine regulatory loop whereby activated chondrocytes may amplify CD95 signals by inducing synthesis of CD95 ligand. Multiple morphologic detection analyses indicated that apoptosis accounted for only a portion of chondrocyte death, whereas the other chondrocytes died by necrosis. Both chondrocyte apoptosis and necrosis depended on the activity of p38 mitogen-activated protein kinase (MAPK) within chondrocytes. Treatment of chondrocytes with the p38 MAPK inhibitor SB203580 abolished anti-CD95 induced cell death by inhibiting the activities of activating transcription factor-2 and caspase-3. In addition, inhibition of p38 MAPK activity in chondrocytes stimulated chondrocyte proliferation, as indicated by 5-bromo-2-deoxyuridine (BrdU) index. Thus, p38 MAPK is a potential therapeutic target, inhibition of which may maintain the cellularity of articular chondrocytes by inhibiting cell death and its amplification signal and by increasing cell proliferation

    Evidence based medicine research of tertiary prevention and management on type 2 diabetes mellitus

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    随着社会文明的进步、生活方式的西化以及人口结构的老龄化,糖尿病的发病率越来越高。因此糖尿病的防治工作至关重要,中国新近提出的慢病管理,关口前移,预防下沉,糖尿病的三级预防也得到日益关注。针对2型糖尿病患者的三级预防目标主要根据自然病程制定:一级预防是通过控制各种危险因素、中止2型糖尿病的发生、降低发病率;二级预防是通过改善胰岛素抵抗和阻止患者胰岛β细胞损害的进展,防止糖尿病各种并发症的发病;三级预防是保护患者残存的胰岛β细胞、加强血糖控制并且控制并发症,全面降低死亡率。本文将从循证医学的角度,总结2型糖尿病三级预防的临床研究证据,结合我们自己科室医护团队的经验心得,为糖尿病预防及管理的合理性及可行性提供理论基础,并对糖尿病的三级预防提出展望。With the progress of social civilization, the Westernization of lifestyle and the aging of population, the incidence of diabetes is increasing. Therefore, the prevention and treatment of diabetes is essential. China’s recently proposed management of chronic diseases, the gateway to move forward, prevention of subsidence, the tertiary prevention of diabetes has also attracted increasing attention. For patients with type 2 diabetes, the tertiary prevention objectives are made according to the natural course of development: primary prevention is to reduce the incidence of the control of risk factors, the incidence of type 2 diabetes, suspension. Second grade prevention is progress by improving insulin resistance and preventing the damage of patients with pancreatic beta cells, and the incidence of various complications of diabetes. Third prevention is the protection of patients remaining islet beta cells, strengthen blood glucose control and control complications, reduce overall mortality. This article summarizes the clinical research evidence of the tertiary prevention of type 2 diabetes from the perspective of evidence-based medicine, combined with the experience of our own medical team. It provides the theoretical basis for the rationality and feasibility of diabetes prevention and management, and puts forward the prospect of the tertiary prevention of diabetes

    System and method for detecting woody breast condition in broilers using image analysis of carcass features

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    This invention relates generally to a system and method of detecting woody breast using image analysis of carcass features, and more particularly to a real-time system and method of detecting woody breast in broilers using non-destructive and/or non-contact image analysis of carcass features. The system and method assess woody breast in broilers at the fillet level using image analysis of the angle or area associated with the tip of the keel bone and surrounding breast meat of broiler carcasses. The method is configured be incorporated into and utilized by vision grading system

    Nanoporous Zeolite Thin Film-Based Fiber Intrinsic Fabry-Perot Interferometric Sensor for Detection of Dissolved Organics in Water

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    A fiber optic intrinsic Fabry-Perot interferometric (IFPI) chemical sensor was developed by fine-polishing a thin layer of polycrystalline nanoporous MFI zeolite synthesized on the cleaved endface of a single mode fiber. The sensor operated by monitoring the optical thickness changes of the zeolite thin film caused by the adsorption of organic molecules into the zeolite channels. The optical thickness of the zeolite thin film was measured by white light interferometry. Using methanol, 2-propanol, and toluene as the model chemicals, it was demonstrated that the zeolite IPFI sensor could detect dissolved organics in water with high sensitivity

    Liparis tianchiensis (Orchidaceae), a new species from Gansu, China

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    Liparis tianchiensis (Orchidaceae, Epidendroideae), a new species from Wenxian County, Gansu Province, China, is described and illustrated, based on morphological characters. Liparis tianchiensis is morphologically similar to L. damingshanensis, L. pauliana and L. mengziensis with erect, lax flowered-inflorescences, small persistent floral bracts, small greenish-purple flowers, spreading sepals, free reflexed and linear petals, a lip with 2 calli near the base and an arcuate column. Liparis tianchiensis differs from L. pauliana by the single and much smaller leaf, shorter sepals and petals, smaller and reflexed oblong lip. It differs from L. mengziensis by having fewer and larger flowers and not connate lip apex. The novelty mostly resembles L. damingshanensis, but can be readily identified by having longer sepals and a reflexed oblong lip. Liparis tianchiensis only occurs in evergreen broad-leaved forest around a mountain lake in Wenxian County, Gansu Province, China

    Galactic Disk Bulk Motions as Revealed by the LSS-GAC DR2

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    We report a detailed investigation of the bulk motions of the nearby Galactic stellar disk, based on three samples selected from the LSS-GAC DR2: a global sample containing 0.57 million FGK dwarfs out to \sim 2 kpc, a local subset of the global sample consisting \sim 5,400 stars within 150 pc, and an anti-center sample containing \sim 4,400 AFGK dwarfs and red clump stars within windows of a few degree wide centered on the Galactic anti-center. The global sample is used to construct a three-dimensional map of bulk motions of the Galactic disk from the solar vicinity out to \sim 2 kpc with a spatial resolution of \sim 250 pc. Typical values of the radial and vertical components of bulk motion range from -15 km s1^{-1} to 15 km s1^{-1}, while the lag behind the circular speed dominates the azimuthal component by up to \sim 15 km s1^{-1}. The map reveals spatially coherent, kpc-scale stellar flows in the disk, with typical velocities of a few tens km s1^{-1}. Bending- and breathing-mode perturbations are clearly visible, and vary smoothly across the disk plane. Our data also reveal higher-order perturbations, such as breaks and ripples, in the profiles of vertical motion versus height. From the local sample, we find that stars of different populations exhibit very different patterns of bulk motion. Finally, the anti-center sample reveals a number of peaks in stellar number density in the line-of-sight velocity versus distance distribution, with the nearer ones apparently related to the known moving groups. The "velocity bifurcation" reported by Liu et al. (2012) at Galactocentric radii 10--11 kpc is confirmed. However, just beyond this distance, our data also reveal a new triple-peaked structure.Comment: 27 pages, 17 figures, Accepted for publication in a special issue of Research in Astronomy and Astrophysics on LAMOST science
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