214 research outputs found
Harnessing Geometric Frustration to Form Band Gaps in Acoustic Channel Lattices
We demonstrate both numerically and experimentally that geometric frustration
in two-dimensional periodic acoustic networks consisting of arrays of narrow
air channels can be harnessed to form band gaps (ranges of frequency in which
the waves cannot propagate in any direction through the system). While resonant
standing wave modes and interferences are ubiquitous in all the analyzed
network geometries, we show that they give rise to band gaps only in the
geometrically frustrated ones (i.e. those comprising of triangles and
pentagons). Our results not only reveal a new mechanism based on geometric
frustration to suppress the propagation of pressure waves in specific frequency
ranges, but also opens avenues for the design of a new generation of smart
systems that control and manipulate sound and vibrations
Evolving Connectivity for Recurrent Spiking Neural Networks
Recurrent spiking neural networks (RSNNs) hold great potential for advancing
artificial general intelligence, as they draw inspiration from the biological
nervous system and show promise in modeling complex dynamics. However, the
widely-used surrogate gradient-based training methods for RSNNs are inherently
inaccurate and unfriendly to neuromorphic hardware. To address these
limitations, we propose the evolving connectivity (EC) framework, an
inference-only method for training RSNNs. The EC framework reformulates
weight-tuning as a search into parameterized connection probability
distributions, and employs Natural Evolution Strategies (NES) for optimizing
these distributions. Our EC framework circumvents the need for gradients and
features hardware-friendly characteristics, including sparse boolean
connections and high scalability. We evaluate EC on a series of standard
robotic locomotion tasks, where it achieves comparable performance with deep
neural networks and outperforms gradient-trained RSNNs, even solving the
complex 17-DoF humanoid task. Additionally, the EC framework demonstrates a two
to three fold speedup in efficiency compared to directly evolving parameters.
By providing a performant and hardware-friendly alternative, the EC framework
lays the groundwork for further energy-efficient applications of RSNNs and
advances the development of neuromorphic devices
Consolidation considering clogging
In land reclamation projects, the vacuum preloading method has been widely used to strengthen dredged fills by removing water. However, during the improvement process, clogging inevitably occurs in the drains and soils, hindering water drainage and causing inhomogeneous consolidation results. Therefore, it is essential to evaluate the effect of clogging on the consolidation behavior of dredged slurry at different radii. In this study, analytical solutions are derived under an uneven strain assumption to calculate the consolidation in the clogging zone and the normal zone, with time-dependent discharge capacity and clogging in the soil considered. Results calculated by the proposed solutions indicated that the clogging effect slows down the development of consolidation, reduces the final consolidation degree, and increases the difference between consolidations at different radii. It is found that the influence of the clogging effect's varies with the speed of the discharge capacity decay, the value of the initial discharge capacity of the drain, the permeability, and the radius of the clogging zone. Finally, a practical application of the proposed solution is discussed, and the proposed solution is suggested for the calculation of consolidation when treating high-water-content slurry
High strength mullite-bond SiC porous ceramics fabricated by digital light processing
Fabricating SiC ceramics via the digital light processing (DLP) technology is of great challenge due to strong light absorption and high refractive index of deep-colored SiC powders, which highly differ from those of resin, and thus significantly affect the curing performance of the photosensitive SiC slurry. In this paper, a thin silicon oxide (SiO2) layer was in-situ formed on the surface of SiC powders by pre-oxidation treatment. This method was proven to effectively improve the curing ability of SiC slurry. The SiC photosensitive slurry was fabricated with solid content of 55 vol% and viscosity of 7.77 Pa s (shear rate of 30 s-1). The curing thickness was 50 μm with exposure time of only 5 s. Then, a well-designed sintering additive was added to completely convert low-strength SiO2 into mullite reinforcement during sintering. Complexshaped mullite-bond SiC ceramics were successfully fabricated. The flexural strength of SiC ceramics sintered at 1550 °C in air reached 97.6 MPa with porosity of 39.2 vol%, as high as those prepared by spark plasma sintering (SPS) techniques.</p
Anomalous crystalline ordering of particles in a viscoelastic fluid under high shear
Addition of particles to a viscoelastic suspension dramatically alters the
properties of the mixture, particularly when it is sheared or otherwise
processed. Shear-induced stretching of the polymers results in elastic stress
that causes a substantial increase in measured viscosity with increasing shear,
and an attractive interaction between particles, leading to their chaining. At
even higher shear rates, the flow becomes unstable, even in the absence of
particles. This instability makes it very difficult to determine the properties
of a particle suspension. Here we use a fully immersed parallel plate geometry
to measure the high-shear-rate behavior of a suspension of particles in a
viscoelastic fluid. We find an unexpected separation of the particles within
the suspension resulting in the formation of a layer of particles in the center
of the cell. Remarkably, monodisperse particles form a crystalline layer which
dramatically alters the shear instability. By combining measurements of the
velocity field and torque fluctuations, we show that this solid layer disrupts
the flow instability and introduces a new, single-frequency component to the
torque fluctuations that reflects a dominant velocity pattern in the flow.
These results highlight the interplay between particles and a suspending
viscoelastic fluid at very high shear rates.Comment: SI Videos and future data sharing are available at
https://doi.org/10.7910/DVN/K0XZ6
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Acute Infection and Subsequent Subclinical Reactivation of Herpes Simplex Virus 2 after Vaginal Inoculation of Rhesus Macaques.
Herpes simplex virus 2 (HSV-2) is a common sexually transmitted infection with a highly variable clinical course. Many infections quickly become subclinical, with episodes of spontaneous virus reactivation. To study host-HSV-2 interactions, an animal model of subclinical HSV-2 infection is needed. In an effort to develop a relevant model, rhesus macaques (RM) were inoculated intravaginally with two or three HSV-2 strains (186, 333, and/or G) at a total dose of 1 × 107 PFU of HSV-2 per animal. Infectious HSV-2 and HSV-2 DNA were consistently shed in vaginal swabs for the first 7 to 14 days after each inoculation. Proteins associated with wound healing, innate immunity, and inflammation were significantly increased in cervical secretions immediately after HSV-2 inoculation. There was histologic evidence of acute herpesvirus pathology, including acantholysis in the squamous epithelium and ballooning degeneration of and intranuclear inclusion bodies in epithelial cells, with HSV antigen in mucosal epithelial cells and keratinocytes. Further, an intense inflammatory infiltrate was found in the cervix and vulva. Evidence of latent infection and reactivation was demonstrated by the detection of spontaneous HSV-2 shedding post-acute inoculation (102 to 103 DNA copies/swab) in 80% of RM. Further, HSV-2 DNA was detected in ganglia in most necropsied animals. HSV-2-specifc T-cell responses were detected in all animals, although antibodies to HSV-2 were detected in only 30% of the animals. Thus, HSV-2 infection of RM recapitulates many of the key features of subclinical HSV-2 infection in women but seems to be more limited, as virus shedding was undetectable more than 40 days after the last virus inoculation.IMPORTANCE Herpes simplex virus 2 (HSV-2) infects nearly 500 million persons globally, with an estimated 21 million incident cases each year, making it one of the most common sexually transmitted infections (STIs). HSV-2 is associated with increased human immunodeficiency virus type 1 (HIV-1) acquisition, and this risk does not decline with the use of antiherpes drugs. As initial acquisition of both HIV and HSV-2 infections is subclinical, study of the initial molecular interactions of the two agents requires an animal model. We found that HSV-2 can infect RM after vaginal inoculation, establish latency in the nervous system, and spontaneously reactivate; these features mimic some of the key features of HSV-2 infection in women. RM may provide an animal model to develop strategies to prevent HSV-2 acquisition and reactivation
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