3,676 research outputs found
The relation between hemispheric lateralisation and measures of immune competence and adherence in Human Immunodeficiency Virus Type 1 (HIV-1)
This is an Open Access article distributed under the terms of the Creative Commons
Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited - Copyright © 2012 Sumner et al
FeH Absorption in the Near-Infrared Spectra of Late M and L Dwarfs
We present medium-resolution z-, J-, and H-band spectra of four late-type
dwarfs with spectral types ranging from M8 to L7.5. In an attempt to determine
the origin of numerous weak absorption features throughout their near-infrared
spectra, and motivated by the recent tentative identification of the E 4\Pi- A
^4\Pi system of FeH near 1.6 microns in umbral and cool star spectra, we have
compared the dwarf spectra to a laboratory FeH emission spectrum. We have
identified nearly 100 FeH absorption features in the z-, J-, and H-band spectra
of the dwarfs. In particular, we have identified 34 features which dominate the
appearance of the H-band spectra of the dwarfs and which appear in the
laboratory FeH spectrum. Finally, all of the features are either weaker or
absent in the spectrum of the L7.5 dwarf which is consistent with the weakening
of the known FeH bandheads in the spectra of the latest L dwarfs.Comment: accepted by Ap
Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity
Virus infection of mammalian cells is sensed by pattern recognition receptors and leads to an innate immune response that restricts virus replication and induces adaptive immunity. In response, viruses have evolved many countermeasures that enable them to replicate and be transmitted to new hosts, despite the host innate immune response. Poxviruses, such as vaccinia virus (VACV), have large DNA genomes and encode many proteins that are dedicated to host immune evasion. Some of these proteins are secreted from the infected cell, where they bind and neutralize complement factors, interferons, cytokines and chemokines. Other VACV proteins function inside cells to inhibit apoptosis or signalling pathways that lead to the production of interferons and pro-inflammatory cytokines and chemokines. In this review, these VACV immunomodulatory proteins are described and the potential to create more immunogenic VACV strains by manipulation of the gene encoding these proteins is discussed
The pupil's response to affective pictures: Role of image duration, habituation, and viewing mode
The pupil has been shown to be sensitive to the emotional content of stimuli. We examined this phenomenon by comparing fearful and neutral images carefully matched in the domains of luminance, image contrast, image color, and complexity of content. The pupil was more dilated after viewing affective pictures, and this effect was (a) shown to be independent of the presentation time of the images (from 100â3,000 ms), (b) not diminished by repeated presentations of the images, and (c) not affected by actively naming the emotion of the stimuli in comparison to passive viewing. Our results show that the emotional modulation of the pupil is present over a range of variables that typically vary from study to study (image duration, number of trials, free viewing vs. task), and encourages the use of pupillometry as a measure of emotional processing in populations where alternative techniques may not be appropriate
Characterization of disturbance sources for LISA: torsion pendulum results
A torsion pendulum allows ground-based investigation of the purity of
free-fall for the LISA test masses inside their capacitive position sensor.
This paper presents recent improvements in our torsion pendulum facility that
have both increased the pendulum sensitivity and allowed detailed
characterization of several important sources of acceleration noise for the
LISA test masses. We discuss here an improved upper limit on random force noise
originating in the sensor. Additionally, we present new measurement techniques
and preliminary results for characterizing the forces caused by the sensor's
residual electrostatic fields, dielectric losses, residual spring-like
coupling, and temperature gradients.Comment: 11 pages, 8 figures, accepted for publication Classical and Quantum
Gravit
Pan-chromatic observations of the remarkable nova LMC 2012
We present the results of an intensive multiwavelength campaign on nova LMC
2012. This nova evolved very rapidly in all observed wavelengths. The time to
fall two magnitudes in the V band was only 2 days. In X-rays the super soft
phase began 135 days after discovery and ended around day 50 after
discovery. During the super soft phase, the \Swift/XRT and \Chandra\ spectra
were consistent with the underlying white dwarf being very hot, 1 MK,
and luminous, 10 erg s. The UV, optical, and near-IR
photometry showed a periodic variation after the initial and rapid fading had
ended. Timing analysis revealed a consistent 19.240.03 hr period in all
UV, optical, and near-IR bands with amplitudes of 0.3 magnitudes which
we associate with the orbital period of the central binary. No periods were
detected in the corresponding X-ray data sets. A moderately high inclination
system, = 6010^{\arcdeg}, was inferred from the early optical
emission lines. The {\it HST}/STIS UV spectra were highly unusual with only the
\ion{N}{5} (1240\AA) line present and superposed on a blue continuum. The lack
of emission lines and the observed UV and optical continua from four epochs can
be fit with a low mass ejection event, 10 M, from a hot
and massive white dwarf near the Chandrasekhar limit. The white dwarf, in turn,
significantly illuminated its subgiant companion which provided the bulk of the
observed UV/optical continuum emission at the later dates. The inferred extreme
white dwarf characteristics and low mass ejection event favor nova LMC 2012
being a recurrent nova of the U Sco subclass.Comment: 18 figures, 6 tables (one online only containing all the photometry
Subaqueous shrinkage cracks in the Sheepbed mudstone: Implications for early fluid diagenesis, Gale crater, Mars
The Sheepbed mudstone, Yellowknife Bay formation, Gale crater, represents an ancient lakebed now exhumed and exposed on the Martian surface. The mudstone has four diagenetic textures, including a suite of early diagenetic nodules, hollow nodules, and raised ridges and later diagenetic light-toned veins that crosscut those features. In this study, we describe the distribution and characteristics of the raised ridges, a network of short spindle-shaped cracks that crosscut bedding, do not form polygonal networks, and contain two to four layers of isopachous, erosion-resistant cement. The cracks have a clustered distribution within the Sheepbed member and transition laterally into concentrations of nodules and hollow nodules, suggesting that these features formed penecontemporaneously. Because of the erosion-resistant nature of the crack fills, their three-dimensional structure can be observed. Cracks that transition from subvertical to subhorizontal orientations suggest that the cracks formed within the sediment rather than at the surface. This observation and comparison to terrestrial analogs indicate that these are syneresis cracksâcracks that formed subaqueously. Syneresis cracks form by salinity changes that cause sediment contraction, mechanical shaking of sediment, or gas production within the sediment. Examination of diagenetic features within the Sheepbed mudstone favors a gas production mechanism, which has been shown to create a variety of diagenetic morphologies comparable to the raised ridges and hollow nodules. The crack morphology and the isopachous, layered cement fill show that the cracks were filled in the phreatic zone and that the Sheepbed mudstone remained fluid saturated after deposition and through early burial and lithification
Fractal Holography: a geometric re-interpretation of cosmological large scale structure
The fractal dimension of large-scale galaxy clustering has been demonstrated
to be roughly from a wide range of redshift surveys. If correct,
this statistic is of interest for two main reasons: fractal scaling is an
implicit representation of information content, and also the value itself is a
geometric signature of area. It is proposed that the fractal distribution of
galaxies may thus be interpreted as a signature of holography (``fractal
holography''), providing more support for current theories of holographic
cosmologies. Implications for entropy bounds are addressed. In particular,
because of spatial scale invariance in the matter distribution, it is shown
that violations of the spherical entropy bound can be removed. This holographic
condition instead becomes a rigid constraint on the nature of the matter
density and distribution in the Universe. Inclusion of a dark matter
distribution is also discussed, based on theoretical considerations of possible
universal CDM density profiles.Comment: 13 pp, LaTeX. Revised version; to appear in JCA
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