Overview of the study design.

<p>Overview of the study design.</p

Summary of results for the three SNPs showing a statistically or marginally significant association in all four stages with breast cancer risk, the Asia Breast Cancer Consortium.

a<p>Effect/reference alleles based on forward strand.</p>b<p>From NCBI genome build 36.</p>c<p>Effect allele frequency in controls.</p>d<p>Adjusted for age and study sites.</p

A regional plot of the −log₁₀P-values for SNPs at 6q25.1.

<p>The LD is estimated using data from HapMap Asian population. Also shown are the SNP Build 36 coordinates in kilobases (Kb), recombination rates in centimorgans (cM) per megabase (Mb) and genes in the region (below) based on the March 2006 UCSC genome browser assembly.</p

Selected characteristics of studies participating in the Asia Breast Cancer Consortium.

a<p>See the methods section for the full names of participating studies.</p>b<p>Mean value for cases/controls.</p>c<p>Percentage for cases/controls.</p>d<p>Significant at α = 0.01 level.</p

ORs per risk allele and 95% CIs for breast cancer associated with three SNPs by study site and ethnicity.

<p>A: rs9485372, B: rs9383951; and C: rs7107217.</p

Principal Component Analysis (PCA) based on the first two eigenvectors obtained by PCA.

<p>A: all individuals from Stage I and HapMap; B: breast cancer cases and controls from Stage I.</p