Analgesic Effects of Lignocaine Alone and in Combination with Meloxicam Administered Epidurally in Dogs Undergoing Femoral Exposure

The experiment was done to evaluate and compare the analgesic effects of lignocaine alone and in combination with meloxicam administered epidurally in dogs undergoing femoral exposure. Eight (n=8) apparently healthy Nigeria local dogs with average weight 9.6kg were used for the research. They were randomly grouped into two groups (A and B) of four dogs each. Pain assessment was done using physiologic parameters (temperature, pulse rate and respiratory rate), haematologic parameters (total WBC count and differential neutrophil count) mined using clinical algometer at o minute and subsequently and 30, 60, 90,120,150 and 180 minutes respectively. The mean values of each parameter were subjected to student t-test with p-values (0.05).Pain threshold showed no significant difference between group A and B (p>0.05).There was no significant difference between the two groups with respect to rectal temperature (p>0.05). For pulse rate, significant difference was observed between group A and B(p<0.05).For respiratory rate, there was significant difference between the two groups (p>0.05).Differential neutrophil count statistical analysis revealed no significant difference between the two groups (p>0.05).There was no significant difference at any time interval between the two groups with respect to Complete White Blood Cell Count(p>0.05).It was concluded that combined lignocaine and meloxicam administered epidurally rendered prolong analgesia than use of lignocaine alone without any postsurgical complication

Analgesic Effects of Lignocaine Alone and in Combination with Meloxicam Administered Epidurally in Dogs Undergoing Femoral Exposure

The experiment was done to evaluate and compare the analgesic effects of lignocaine alone and in combination with meloxicam administered epidurally in dogs undergoing femoral exposure. Eight (n=8) apparently healthy Nigeria local dogs with average weight 9.6kg were used for the research. They were randomly grouped into two groups (A and B) of four dogs each. Pain assessment was done using physiologic parameters (temperature, pulse rate and respiratory rate), haematologic parameters (total WBC count and differential neutrophil count) mined using clinical algometer at o minute and subsequently and 30, 60, 90,120,150 and 180 minutes respectively. The mean values of each parameter were subjected to student t-test with p-values (0.05).Pain threshold showed no significant difference between group A and B (p>0.05).There was no significant difference between the two groups with respect to rectal temperature (p>0.05). For pulse rate, significant difference was observed between group A and B(p<0.05).For respiratory rate, there was significant difference between the two groups (p>0.05).Differential neutrophil count statistical analysis revealed no significant difference between the two groups (p>0.05).There was no significant difference at any time interval between the two groups with respect to Complete White Blood Cell Count(p>0.05).It was concluded that combined lignocaine and meloxicam administered epidurally rendered prolong analgesia than use of lignocaine alone without any postsurgical complication