5,090 research outputs found
Transient non-isothermal model of a polymer electrolyte fuel cell
In this paper we present a one-dimensional transient model for the membrane electrode assembly of a polymer-electrolyte fuel cell. In earlier work we established a framework to describe the water balance in a steady-state, non-isothermal cathode model that explicitly included an agglomerate catalyst layer component. This paper extends that work in several directions, explicitly incorporating components of the anode, including a micro-porous layer, and accounting for electronic potential variations, gas convection and time dependence. The inclusion of temperature effects, which are vital to the correct description of condensation and evaporation, is new to transient modelling. Several examples of the modelling results are given in the form of potentiostatic sweeps and compared to experimental results. Excellent qualitative agreement is demonstrated, particularly in regard to the phenomenon of hysteresis, a manifestation of the sensitive response of the system to the presence of water. Results pertaining to pore size, contact angle and the presence of a micro-porous layer are presented and future work is discussed
Relative Stability of Network States in Boolean Network Models of Gene Regulation in Development
Progress in cell type reprogramming has revived the interest in Waddington's
concept of the epigenetic landscape. Recently researchers developed the
quasi-potential theory to represent the Waddington's landscape. The
Quasi-potential U(x), derived from interactions in the gene regulatory network
(GRN) of a cell, quantifies the relative stability of network states, which
determine the effort required for state transitions in a multi-stable dynamical
system. However, quasi-potential landscapes, originally developed for
continuous systems, are not suitable for discrete-valued networks which are
important tools to study complex systems. In this paper, we provide a framework
to quantify the landscape for discrete Boolean networks (BNs). We apply our
framework to study pancreas cell differentiation where an ensemble of BN models
is considered based on the structure of a minimal GRN for pancreas development.
We impose biologically motivated structural constraints (corresponding to
specific type of Boolean functions) and dynamical constraints (corresponding to
stable attractor states) to limit the space of BN models for pancreas
development. In addition, we enforce a novel functional constraint
corresponding to the relative ordering of attractor states in BN models to
restrict the space of BN models to the biological relevant class. We find that
BNs with canalyzing/sign-compatible Boolean functions best capture the dynamics
of pancreas cell differentiation. This framework can also determine the genes'
influence on cell state transitions, and thus can facilitate the rational
design of cell reprogramming protocols.Comment: 24 pages, 6 figures, 1 tabl
Inertial coalescence of droplets on a partially wetting substrate
We consider the growth rate of the height of the connecting bridge in rapid surface-tension-driven coalescence of two identical droplets attached on a partially wetting substrate. For a wide range of contact angle values, the height of the bridge grows with time following a power law with a universal exponent of 2/3, up to a threshold time, beyond which a 1/2 exponent results, that is known for coalescence of freely-suspended droplets. In a narrow range of contact angle values close to 90°, this threshold time rapidly vanishes and a 1/2 exponent results for a 90° contact angle. The argument is confirmed by three-dimensional numerical simulations based on a diffuse interface method with adaptive mesh refinement and a volume-of-fluid method
Preference-Based Learning for Exoskeleton Gait Optimization
This paper presents a personalized gait optimization framework for lower-body exoskeletons. Rather than optimizing numerical objectives such as the mechanical cost of transport, our approach directly learns from user preferences, e.g., for comfort. Building upon work in preference-based interactive learning, we present the CoSpar algorithm. CoSpar prompts the user to give pairwise preferences between trials and suggest improvements; as exoskeleton walking is a non-intuitive behavior, users can provide preferences more easily and reliably than numerical feedback. We show that CoSpar performs competitively in simulation and demonstrate a prototype implementation of CoSpar on a lower-body exoskeleton to optimize human walking trajectory features. In the experiments, CoSpar consistently found user-preferred parameters of the exoskeleton’s walking gait, which suggests that it is a promising starting point for adapting and personalizing exoskeletons (or other assistive devices) to individual users
Iterative CZT-based frequency offset estimation for frequency-selective channels
In this paper, we present an accurate frequency offset estimation method for frequency-selective channels. Through the iterative use of the chirp z-transform (CZT) algorithm, an accurate frequency offset estimator is proposed, approaching the Cramer-Rao Bound (CRB) even at low signal-to-noise ratio (SNR). Further, the estimation can be achieved within one block of training sequence, thus avoiding the transmission of repetitive known blocks as is usually required in many conventional methods. Meanwhile, the overall complexity is acceptable. More importantly, the CZT operation can utilize the fast Fourier transform (FFT) structure that is favourable for digital signal processor (DSP) implementation. Simulation results show that two or at most three iterations of the CZT computation are sufficient for an accurate frequency offset estimation in the SNR range from 0 dB to 30 dB. © 2005 IEEE.published_or_final_versio
A Study on Effects of Process Parameters in Rapid Freeze Prototyping
Rapid Freeze Prototyping (RFP) is a relatively new solid freeform fabrication
process, which builds a three-dimensional part according to a CAD model by depositing
and freezing water droplets layer by layer. A study on the effects of RFP process
parameters including the nozzle scanning speed, droplet size, and droplet frequency in
building ice parts with a single-nozzle work head is made. Presented in this paper are the
results of this study which indicate that these process parameters determine the ice layer
thickness and ice line width, which in turn determine the surface roughness and the
waiting time required after depositing each layer of water (i.e. between successive layers)
during the ice part building process.This project is supported by a National Science Foundation Grant (DMI-0128313)
and a Department of Education GAANN Fellowship Grant (P200A010446).Mechanical Engineerin
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