Analisis Rasionalisasi Kandungan Ramuan Diabetes Mellitus di Laboratorium Penelitian dan Pengembangan Pelayanan Pengobatan Obat Tradisional (Lp4ot)

Herbal medicines consist of sambiloto (Andrographis paniculata), salam (Eugenia polyantha) and temulawak (Curcuma xanthorriza) are used as a formula for Non Insulin Dependent Diabetes Mellitus (NIDDM) in Traditional Medicines Clinic. A literature study was conducted to find out the rationality of the treatment has run by the clinic. Results of this study indicated that sambiloto and salam have hypoglycemic activity. Furthermore temulawak have cholesterol regulator and lever protector activities. It concludes that Diabetes Mellitus therapy from herbal medicines which are contained of sambiloto, salam, and temulawak are rational for the NIDDM. Key words: diabetes mellitus, Andrographis paniculata, Curcuma xanthorriza, Eugenia polyanth

Studi Pemanfaatan dan Keamanan Kombinasi Metformin dengan Ekstrak Campuran Andrographis Paniculatadan Syzygium Polyanthum untuk Pengobatan Diabetes Mellitus (Preliminary Study)

Background: Use of Andrographis paniculata and Syzigium polyanthum have been used widely, on the contrary the benefit and safety have not been scientifically proven. This study aimed to overview and analyze benefit and safety the extract of Andrographis paniculata and Syzigium polyanthum mixture to decrease blood glucose concentration. Methods: It was an experiment study among intervension and control groups by a block random sampling with pre-post test design. Data were collected by questionnaires and also data among intervension group, therapy of conventional antidiabetic of metformin in combination to the herbal extract of Andrographis paniculata and Syzigium polyanthum mixture (1: 1) with among control group, of metformin. A total samples of 30 Diabetes Mellitus respondents were selected among males or females, aged 40-60 years with blood glucose concentration of 140-220 mg/dl, has no history of hypertension or has mild hypertension. The samples were devided in 2 groups composed of 15 persons among intervsion and 15 persons among control groups, respectively The intervension group was given metformin 500 mg once a day in the morning taken 15 minutes after breakfast in combination to the extract of Andrographis paniculata and Syzigium polyanthum mixture (1: 1) of 700 mg. The control group was given metformin 500 mg on ce a day in the morning taken 15 minutes after breakfast in combination to placebo. The duration of therapy was 4 weeks. Data were taken by anamnesa, physical diagnose, laboratory examination offasting blood glucose and Oral Glucose Tolerance Test (OGTT) in every week. Meanwhile for examination side effects on liver and run function test in every 2 (two) week. The data were analyzed descriptively and t test. Results: Results showed that the intervension group given metformin in combination to the extract of Andrographis paniculata and Syzigium polyanthum mixture (1:1) of 700 mg could significantly decrease fasting blood glucose but could not significantly decrease OGTT in comprasion to control group given metformin with placebo. There were no side effects on liver and kidney function test in the therapy of herbal extract of Andrographis paniculata and Syzigium polyanthum mixture in duration of 4 we eks. It concluded that the herbal extract of Andrographis paniculata and Syzigium polyanthum mixture is safe

PROSEDUR PEMBERIAN KREDIT MULTI GUNA (KMG) TERHADAP GOLONGAN PENGHASILAN TETAP Studi kasus pada PT. Bank Rakyat Indonesia (Persero) Tbk. Cabang Bogor Dewi Sartika

Prosedur pemberian kredit merupakan hal penting dalam penentuan kelayakan dan sebagai patokan dalam mengambil keputusan apakah debitur tersebut layak ataukah tidak untuk menerima kredit yang telah disediakan oleh bank. Tidak hanya itu prosedur pemberian kredit juga merupakan sistem dan prosedur yang telah ditetapkan oleh suatu bank untuk memudahkan pihak bank dalam menjalankan fungsinya sebagai penyalur dana kepada masyarakat dalam bentuk kredit dengan sistematika dan alur yang rapih dan tersusun sehingga dapat memudahkan bank untuk menilai prosfek dalam pemberian kredit. Tujuan pembahasan ini adalah untuk mengetahui prosedur pemberian kredit multiguna pada golongan penghasilan tetap di salah satu bank milik pemerintah yang mempunyai fasilitas kredit multiguna. Pembahasan dilakukan untuk mengetahui bagaimana sebenarnya pemberian kredit multiguna pada golongan penghasilan tetap tersebut berjalan dengan baik atau belum. Penelitian yang dilakukan Penulis adalah di PT. Bank Rakyat Indonesia (Persero) Tbk Cabang Bogor Dewi Sartika. Hasil Pembahasan menunjukan bahwa PT. Bank Rakyat Indonesia (Persero) Tbk Cabang Bogor Dewi Sartika telah menerapkan sistem prosedur pemberian kredit yang baik. Penilain kelayakan debitur untuk menerima kredit serta proses pemberian kredit yang sudah cukup baik. Untuk memastikan bahwa Prosedur Pemberian Kredit Multiguna sudah cukup baik, dalam pemberian kredit pihak bank selalu menggunakan syarat dan ketentuan yang telah ditetapkan oleh PT. Bank Rakyat Indonesia (Persero) Tbk. Hasil evaluasi dari pembahasan ini menunjakan bahwa Kredit Multiguna merupakan kredit yang dapat digunakan untuk berbagai keperluan konsumtif (consumtive purpose) sepanjang tidak bertentangan dengan ketentuan perundang-undangan yang berlaku, yang menambah variasi jenis kredit yang ada dalam perbankan yang kebayakan merupakan kredit yang dipergunkan untuk investasi dan modal kerja. Kata kunci : Prosedur, Kredit, Multigun

Efek Pemberian Ramuan Ekstrak Delima Putih, Kunyit dan Beluntas untuk Pengobatan 'Flour Albus'

A clinical trial have been conducted during April 1997 to March 1998 in Surabaya. This study tested the effectiveness of tradisional medicine for treating vaginal discharge problem (Papaniculoan test) among woman. The traditional medicine consist of three medical plants (Piucheae indicae folium, Curcumae domesticae rhizoma and Granati fructus contex) which were k nown as anti macro organism 35 married women using oral pill have been evaluated to see the respond of the treatment. The result of the study showed that the traditional medicine was not effective for treating purulent inframation caused by bacteria. It was also not effective to kill trichomonas and fungi. The patient of non spesific inflamation (Pap test) have been cured by traditional medicine. This treatment did not damage the liver and kidney function seen by blood examination (SGOT, SGPT, BUN, Creatinin). This study concluded that the traditional medicine was not effective to cure vaginal diagnosed as purulent inflamation, trichomonas and fungi (Pap test), but it supposed to be suggested to use in the first step of treatment by the women themselves before they seek the medical treatment. It was safe for liver and kidney in the shorterm USAge

Pengaruh Polivinilpirolidon K-30 terhadap Peningkatan Laju Disolusi Andrografolida dengan Sistem Dispersi Solida

Andrographolide is the main constituent of Andrographis paniculata Ness which was poorly soluble in water. As diterpenoid lactone andrographolide has many biological activity, some of them ara immunostimulant, antimalaria, hepatoprotector and anti mutagenic. The objectives of this study were to find out influence of polyvinylpirrolidon (PVP) K-30 to increase dissolution rate of andrographolide by solid dispersion in water and dissolution media pH 8,0. In this research andrographolide were divided in 6 groups that are physical mixture and solid dispersion by ratio 1:3; 1:5 and 1:9. Result of these study showed that the X-ray difraction patterns of physical mixture have crystal intensity as same as andrographolide crystal. But solid dispersion showed lower intensity. The solid dispersion system increase dissolution rate of andrographolide isolate. Increasing of dissolution rate a function of the ratio of drug to PVP used. Studies of dissolution rate have shown that coprecipitate of andrographolide-PVP K-30 (1:9) is better combination than 1:5 and 1:3

Rekayasa Penyuluhan Kesehatan untuk Meningkatkan Kepedulian Kehamilan melalui Organisasi Sosial Wanita Setempat

The purpose of this study is to determine performance effectivity of the local woman social organization (PKK and Fatayat NU) in order to increase the health care of pregnant woman. The first step of this study is to create the community health education guidance, consist of two manual books that are Technical of pregnant health education instruction, and other one is the manual of hedlth education Matenal. Both of the manuals invented based on local cultural style and to have the disposal of Madura's language. The study area consist of three districts in Madura Bangkalan Regency (PKK 's area, Fatayat 's area, and Control 's area) with high infant mortality rate, high maternal mortality rate, and low rate deliveries assisted by profesional health worker. The respondents that is pregnant womans. The study showed that health education is an intervention to increase respondent's knowledge and attitude for effort of health care pregnancy. The knowledge and attitude increase as specially on pregnant indication, mother breast care, personal hygiene for pregnant woman specially, pregnant health care control at Health Centre, pregnant immumzation, delivery by profesional health workers, ante natal care, and family planning method for ante natal. Based on provider as educator this study showed after health education intervention, the effectiveness PKK 's community area is better than Fatayat's area

Hubungan Pola Penggunaan Rokok dengan Tingkat Kejadian Asma

Tobacco use behaviors are known as determination factor of respiratory diseases as bronchial asthma. Secondary data of Basic Health Research 2007/2008 from samples of people aged ≥ 10 years old were analyzed to provide the description of tobacco use behaviors and the associations to bronchial asthma cases. The total samples were 15.254 people. Multiple Logistic Regression technique was applied to analyze the association. Results showed that tobacco use behavior (smoking behavior) was 29.7%, while prevalence of bronchial asthma cases was 1.99%. The smokers tended increase according to higher age groups and also to higher education. The smokers were lightly higher (52.6%) among females. For education the mayority of smokers were 47.02% unemployee followed by 37.42% for services/farmer/workers/others. The multivariate analysis showed that smokers of “kretek” cigarretes had risk 1.3 times (OR = 1.336) compared to smokers of others than “kretek” cigarettes, at age, sex, education, occupation constant. We suggest the government to pressure the implementation of law on tobacco and to enhance the community knowledge and awareness on dangers of tobacco use in order to prevent people from respiratory diseases