Automatic Generation of 3D Building Models with Efficient Solar Photovoltaic Generation

To facilitate public involvement for sustainable development, 3D models simulating real or near future cities using 3D Computer Graphics (CG) can be of great use. 3D city models are important in environmentally friendly urban planning that will use solar photovoltaic (PV) generation. However, enormous time and labour has to be consumed to create these 3D models using 3D modelling software such as 3ds Max or SketchUp. In order to automate laborious steps, this paper proposes a Geographic Information System (GIS) and CG integrated system that automatically generates 3D building models based on building polygons or building footprints on digital maps, which show most building polygons’ edges meet at right angles (orthogonal polygon). A complicated orthogonal polygon can be partitioned into a set of rectangles. The proposed integrated system partitions orthogonal building polygons into a set of rectangles and places rectangular roofs and box-shaped building bodies onto these rectangles. In this paper, for placing solar panels on a hipped roof, the structure of an ordinary hipped roof that is made up of two triangular roof boards and two trapezoidal ones is clarified. To implement efficient PV generation, this paper proposes to automatically generate 3D building models for buildings topped with double shed roofs with overlaid PV arrays. The sizes and positions, slopes of roof boards and main under roof constructions are made clear by presenting a top view and side view of a double shed roof house. For the applied example of the developed system, this papers presents a simulation of the solar photovoltaic generation change of a city block by performing land readjustment and changing the shape of buildings, ordinarily roofed houses or double shed roofed houses suitable for efficient PV generation. Our simulation reveals that double shed roofed houses have greatly improved solar photovoltaic generation

Prognostic value of RKIP and p-ERK in gastric cancer

<p>Abstract</p> <p>Background</p> <p>The mitogen-activated protein kinase (MAPK) signaling pathway participates in several steps of tumour development and is considered a prominent therapeutic target for the design of chemotherapeutic agents. We evaluated the expressions of extracellular signal-regulated kinase (ERK), mitogen-activated protein kinase (MEK), an upstream regulator of ERK, and Raf kinase inhibitor protein (RKIP), and investigated correlations of these expressions with clinicopathological features and outcomes in gastric cancer.</p> <p>Methods</p> <p>Tumour samples were obtained from 105 patients with gastric adenocarcinomas who underwent radical gastrectomy. The expressions of phosphorylated ERK (p-ERK), phosphorylated MEK (p-MEK), and RKIP were analysed by immunohistochemical staining.</p> <p>Results</p> <p>Expression of RKIP, p-MEK, and p-ERK was found in 69 (66%), 54 (51%), and 64 (61%) of all tumours, respectively. RKIP expression negatively correlated with the depth of invasion (p < 0.001), lymph node involvement (p = 0.028), and Union for International Cancer Control (UICC) stage (p = 0.007). RKIP expression was associated with significantly longer relapse-free survival (RFS) (p = 0.0033), whereas p-MEK was not (p = 0.79). Patients with p-ERK expression had slightly, but not significantly shorter RFS than those without such expression (p = 0.054). Patients with positive p-ERK and negative RKIP expression had significantly shorter RFS than the other patients (p < 0.001). The combination of RKIP and p-ERK expression was an independent prognostic factor (hazard ratio, 2.4; 95% confidence interval, 1.3 - 4.6; p = 0.008).</p> <p>Conclusions</p> <p>Our results demonstrated that loss of RKIP was associated with tumour progression and poor survival. Negative RKIP expression combined with positive p-ERK expression was an independent predictor of poor outcomes in patients with gastric cancer.</p

Colorectal Carcinoma: Local Tumor Staging and Assessment of Lymph Node Metastasis by High-Resolution MR Imaging in Surgical Specimens

Purpose. To assess the accuracy of high-resolution MR imaging as a means of evaluating mural invasion and lymph node metastasis by colorectal carcinoma in surgical specimens. Materials and Methods. High-resolution T1-weighted and T2-weighted MR images were obtained in 92 surgical specimens containing 96 colorectal carcinomas. Results. T2-weighted MR images clearly depicted the normal colorectal wall as consisting of seven layers. In 90 (94%) of the 96 carcinomas the depth of mural invasion depicted by MR imaging correlated well with the histopathologic stage. Nodal signal intensity on T2-weighted images (93%) and nodal border contour (93%) were more accurate than nodal size (89%) as indicators of lymph node metastasis, and MR imaging provided the highest accuracy (94%–96%) when they were combined. Conclusion. High-resolution MR imaging is a very accurate method for evaluating both mural invasion and lymph node metastasis by colorectal carcinoma in surgical specimens

(Study on Agricultural Management for Sustainable Agriculture in Zhangye Oasis, Middle Reaches of Heihe River Basin)

Photovoltaic (PV) installation potential on residential building envelope in equatorial region was analysed by 3D insolation colour rendering employing BIM Revit solar analysis tool. Monthly global solar radiation calculation was employed to investigate solar potential in study case area. Actual energy consumption of residential sector was used as a base to predict energy demand for next 10 years. Predicted energy demand was then used to calculate the area needed for photovoltaic installation to balance future energy demand. The energy consumption by residential building was divided into five different installed electrical power capacities namely 450 Watt, 900 Watt, 1300 Watt, 2200 Watt and 3500-6600 Watt. Study results suggest that the potential location of photovoltaic panel installation on detached houses is on the roof, East, and West walls. Abundant solar energy in equatorial region was proved by high potential of PV energy generation 7 – 9 kW/m² for amorphous silicon, 17 – 18 kW/m² for polycrystalline silicon, and 19 – 23 kW/m² for monocrystalline silicon. The roof element alone can provide sufficient electrical energy generated by installed photovoltaic panels for the next 10 years. The area needed to supply 450W – 6600W installed power capacity were 13 – 75 m² for monocrystalline silicon, 23 – 120 m² for polycrystalline silicon, and 50 – 259 m² for amorphous silicon. To conclude, implementation of photovoltaic installations on residential buildings have a huge potential to secure not only recent energy consumption, but also future energy demand

Renal shear wave velocity by acoustic radiation force impulse did not reflect advanced renal impairment

[Aim] Acoustic radiation force impulse is a noninvasive method for evaluating tissue elasticity on ultrasound. Renal shear wave velocity measured by this technique has not been fully investigated in patients with renal disease. The aim of the present study was to compare renal shear wave velocity in end‐stage renal disease patients and that in patients without chronic kidney disease and to investigate influencing factors. [Methods] Renal shear wave velocities were measured in 59 healthy young subjects (control group), 31 subjects without chronic kidney disease (non‐CKD group), and 39 end‐stage renal disease patients (ESRD group). Each measurement was performed 10 times at both kidneys, and the mean value of eight of 10 measurements, excluding the maximum and minimum values, was compared. [Results] Renal shear wave velocity could be measured in all subjects. Renal shear wave velocity in the control group was higher than in the non‐CKD group and in the ESRD group, and no difference was found between the non‐CKD group and the ESRD group. Age and depth were negatively correlated to the renal shear wave velocity. In multiple regression analysis, age and depth were independent factors for renal shear wave velocity, while renal impairment was not. There was no difference between the non‐CKD group and the ESRD group, even when ages were matched and depth was adjusted. [Conclusion] Renal shear wave velocity was not associated with advanced renal impairment. However, it reflected alteration of renal aging, and this technique may be useful to detect renal impairment in the earlier stages

Simultaneous medial opening wedge high tibial osteotomy and revision anterior cruciate ligament reconstruction using a bone-patella tendon-bone graft: A case report

It is said that the clinical results of cases with anterior cruciate ligament reconstruction (ACLR) who have knee osteoarthritis (OA) are not very good. A case of simultaneous medial opening wedge high tibial osteotomy (MOWHTO) and revision ACLR using a bone-patella tendon-bone (BPTB) graft for medial knee OA after re-tear of a reconstructed ACL graft is reported. The patient was a 49-year-old man who underwent surgery for a right knee ACL injury by ACLR using an ipsilateral hamstring tendon graft 7 years earlier. He sprained his right knee while he was skiing and injured his reconstructed ACL graft. He had knee instability and pain at the medial side of his knee. X-ray showed a tibia vara deformity and medial knee OA of Kellgren-Lawrence grade II. It was thought that the medial knee pain would remain if he were treated by revision ACLR alone. Therefore, simultaneous MOWHTO and revision ACLR using an ipsilateral BPTB graft were performed. The excellent clinical results and radiological findings 3 years after the operation indicate the usefulness of this approach

Study protocol of the SACURA trial: a randomized phase III trial of efficacy and safety of UFT as adjuvant chemotherapy for stage II colon cancer

BACKGROUND: Adjuvant chemotherapy for stage III colon cancer is internationally accepted as standard treatment with established efficacy, but the usefulness of adjuvant chemotherapy for stage II colon cancer remains controversial. The major Western guidelines recommend adjuvant chemotherapy for “high-risk stage II” cancer, but this is not clearly defined and the efficacy has not been confirmed. METHODS/DESIGN: SACURA trial is a multicenter randomized phase III study which aims to evaluate the superiority of 1-year adjuvant treatment with UFT to observation without any adjuvant treatment after surgery for stage II colon cancer in a large population, and to identify “high-risk factors of recurrence/death” in stage II colon cancer and predictors of efficacy and adverse events of the chemotherapy. Patients aged between 20 and 80 years with curatively resected stage II colon cancer are randomly assigned to a observation group or UFT adjuvant therapy group (UFT at 500–600 mg/day as tegafur in 2 divided doses after meals for 5 days, followed by 2-day rest. This 1-week treatment cycle is repeated for 1 year). The patients are followed up for 5 years until recurrence or death. Treatment delivery and adverse events are entered into a web-based case report form system every 3 months. The target sample size is 2,000 patients. The primary endpoint is disease-free survival, and the secondary endpoints are overall survival, recurrence-free survival, and incidence and severity of adverse events. In an additional translational study, the mRNA expression of 5-FU-related enzymes, microsatellite instability and chromosomal instability, and histopathological factors including tumor budding are assessed to evaluate correlation with recurrences, survivals and adverse events. DISCUSSION: A total of 2,024 patients were enrolled from October 2006 to July 2010. The results of this study will provide important information that help to improve the therapeutic strategy for stage II colon cancer. TRIAL REGISTRATION: ClinicalTrials.gov NCT00392899