Thymic Carcinoma (TC) is a rare tumor among the epithelial tumors of the thymus with a challenging diagnosis for pathologists. A case report, a 55-year-old male patient complained of coughing, chest pain, and intermittent shortness of breath for 2 weeks before being referred. Patient underwent radiological examination, surgery, histopathological examination and immunohistochemical examination to reach the definitive diagnosis. The histopathological examination of Thymic Squamous Cell Carcinoma was established with immunohistochemical examination