219 research outputs found
Prescription opioid and benzodiazepine misuse is associated with suicidal ideation in older adults
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147198/1/gps4999_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/147198/2/gps4999.pd
Residential Mobility, Transience, Depression, and Marijuana Use Initiation Among Adolescents and Young Adults
Marijuana Use, Recent Marijuana Initiation, and Progression to Marijuana Use Disorder Among Young Male and Female Adolescents Aged 12-14 Living in US Households
Marijuana use/nonuse among those aged 50+: comparisons of use-to-nonuse, initiation/reinitiation, and continued use over 24 months
Genetic and environmental risk factors in the non-medical use of over-the-counter or prescribed analgesics, and their relationship to major classes of licit and illicit substance use and misuse in a population-based sample of young adult twins
Background and Aims: The non-medical use of over-the-counter or prescribed analgesics (NMUA) is a significant public health problem. Little is known about the genetic and environmental etiology of NMUA and how these risks relate to other classes of substance use and misuse. Our aims were to estimate the heritability NMUA and sources of genetic and environmental covariance with cannabis and nicotine use, cannabis and alcohol use disorders and nicotine dependence in Australian twins. Design: Biometrical genetic analyses or twin methods using structural equation univariate and multivariate modeling. Setting: Australia. Participants: A total of 2007 young adult twins [66% female; ÎŒ\ua0=\ua025.9, standard deviation (SD)\ua0=\ua03.6, range\ua0=\ua018â38] from the Brisbane Longitudinal Twin Study retrospectively assessed between 2009 and 2016. Measurements: Self-reported NMUA (non-opioid or opioid-based), life-time nicotine, cannabis and opioid use, DSM-V cannabis and alcohol use disorders and the Fagerström Test for Nicotine Dependence. Findings: Life-time NMUA was reported by 19.4% of the sample. Univariate heritability explained 46% [95% confidence interval (CI)\ua0=\ua00.29â0.57] of the risks in NMUA. Multivariate analyses revealed that NMUA is moderately associated genetically with cannabis (r\ua0=\ua00.41) and nicotine (r\ua0=\ua00.45) use and nicotine dependence (r\ua0=\ua00.34). In contrast, the genetic correlations with cannabis (r\ua0=\ua00.15) and alcohol (r\ua0=\ua00.07) use disorders are weak. Conclusions: In young male and female adults in Australia, the non-medical use of over-the-counter or prescribed analgesics appears to have moderate heritability. NMUA is moderately associated with cannabis and nicotine use and nicotine dependence. Its genetic etiology is largely distinct from that of cannabis and alcohol use disorders
Older-Adult Marijuana Users in Substance Use Treatment: Characteristics Associated with Treatment Completion
Classic psychedelic use is associated with reduced psychological distress and suicidality in the United States adult population
Femaleâmale differences in alcohol dependence levels: Evidence on newly incident adolescent and youngâadult drinkers in the United States, 2002â2014
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