Kinetic Spectrophotometric Determination of Propellant Grade Hydrazines using Thiophenes with Active Carbonyl Groups

A simple, cost effective, highly sensitive and rapid kinetic spectrophotometric method was developed for hydrazines by using Thiophene-3-carboxaldehyde (3-Thienaldehyde) and 3-Butenone (E)-1,1,1-trifluoro-4-(3-thienyl) (CF3 enone). CF3 enone was prepared by crossed aldol condensation of 3-Thienaldehyde and characterized by UV-Vis, FT-IR and NMR spectra. Reactions of 3-Thienaldehyde (with catalyst) and CF3 enone (in acetonitrile medium without catalyst) with hydrazines were followed spectrophotometrically and compared. Variables such as temperature and concentration were optimized to determine hydrazines in the concentration range of 0.1 mM to 0.1 M for 3-Thienaldehyde and 0.1 mM to 1 mM for CF3 enone. Minimum detectable limits were found to be 0.2 mM (Hydrazine) and 0.1 mM (MMH ) for 3-Thienaldehyde. For CF3 enone, Minimum detectable limits were found to be 0.007 mM (Hydrazine) and 0.01 mM (MMH). Rate of the CF3 enone reaction was studied as there is gradual decrease in absorbance for the peak at 320 nm for the interaction of hydrazines. Initial rate and fixed time methods were adopted for kinetic study. CF3 enone based kinetic spectrophotometric method is rapid and sensitive with no catalyst requirement for interaction of hydrazines when compared with the classical CHO functional group based method.Defence Science Journal, Vol. 64, No. 1, January 2014, DOI:10.14429/dsj.64.309

Binding of activated isoniazid with acetyl-CoA carboxylase from Mycobacterium tuberculosis

AccD6 (acetyl coenzyme A (CoA) carboxylase), plays an important role in mycolic acid synthesis of Mycobacterium tuberculosis (Mtb). Induced gene expression by isoniazid (isonicotinylhydrazine - INH), anti-tuberculosis drug) shows the expression of accD6. It is our interest to study the binding of activated INH with the AccD6 model using molecular docking procedures. The study predicts a primary binding site for activated INH (isonicotinyl acyl radical) in AccD6 as a potential target

Design of Barrage Style Tidal Water Power Plant Structure to Reduce Sediment Accretions in Approach Channel, Entrance, Harbour and Backwaters of Cannanore Port, Kerala

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

An Introduction to Survival Analytics, Types, and Its Applications

In today’s world, data analytics has become the integral part of every domain such as IOT, security, healthcare, parallel systems, and so on. The importance of data analytics lies at the neck of what type of analytics to be applied for which integral part of the data. Depending upon the nature and type of data, the utilization of the analytical types may also vary. The most important type of analytics which has been predominantly used up in health-care sector is survival analytics. The term survival analytics has originated from a medical domain of context which in turn determines and estimates the survival rate of patients. Among all the types of data analytics, survival analytics is the one which entirely depends upon the time and occurrence of the event. This chapter deals with the need for survival data analytics with an explanatory part concerning the tools and techniques that focus toward survival analytics. Also the impact of survival analytics with the real world problem has been depicted as a case study

Suicide prevention strategies: An overview of current evidence and best practice elements

Suicide is a complex human behavior with multiple interacting determinants. Clinicians and practitioners often face difficulties in assimilating the evidence base for suicide prevention interventions, evaluating their effectiveness and decoding the best practice elements of each approach. In this article, we do not aim to provide an exhaustive coverage of every approach. Instead, we provide an overview of the following eight major suicide prevention interventions: awareness programs, screening, gatekeeper training, access to means restriction, follow-up care, hotlines, media strategies, pharmacotherapeutic and psychotherapeutic approaches. The evidence base and components of each approach are described to facilitate replication. The best practice elements are synthesized from each approach and presented to aid program development and practice. Although a number of approaches hold promise, there are difficulties in ascertaining the effective elements under each of them. Innovative research designs are needed to address this knowledge gap as it will facilitate optimal allocation of resources for suicide prevention

Choroterpes (Choroterpes) kaegies Selvakumar & Subramanian & Chandra & Jehamalar 2017, sp. n.

<i>Choroterpes</i> (<i>Choroterpes</i>) <i>kaegies</i> Selvakumar, Subramanian & Chandra sp. n. (Figs 1–16) <p> <b>Material examined.</b> Holotype: 1 larva, INDIA, Meghalaya, East Khasi Hills, Khrang village, Wankwar River, 25.32481 N, 91.77519 E, 1658 m, 02.iii.2016, coll. E. Eyarin Jehamalar (Reg. No. 5144). Paratypes: 5 larvae, same data as holotype; 2 larvae, Meghalaya, East Khasi Hills, Thangasalai village, Umkhen River, 25.59186 N, 92.05494 E, 937 m, 05.iii.2016, coll. E. Eyarin Jehamalar (Reg. No. 5147/H13); 1 larva, Meghalaya, East Garo Hills, Upper Rongbu village, 25.91615 N, 90.83157 E, 101 m, 26.vi.2016, coll. E. Eyarin Jehamalar (Reg. No. 5149/H13); 1 larva, Himachal Pradesh, Bilaspur district, Mandodari, River stream, 31.783 N, 76.332 E, 18.xi.2012, coll. K.A. Subramanian.</p> <p> <b>Description.</b> Body length 4.6–5.0 mm (Fig. 1). Antennae approximately 3.0 mm. Head prognathous, light yellowbrown with diffuse black markings. Labrum with 3 transverse, near parallel, rows of setae on dorsal surface, both distal and proximal transverse setal rows regular; anteromedian emargination broad (Fig. 2). Lingua of hypopharynx with well developed lateral process, anterior margin cleft (Fig. 3). Lateral margins of mandibles with scattered setae, inner mandibular incisor slightly longer than outer one (Figs 4–5). Maxillary palp 3 segmented; segment 2 subequal in length to segment 1, segment 3 approximately ¾ length of segment 2 (Fig. 6). Labium: glossa with thick plate-like setae on ventral surface, fewer setae on dorsal surface; paraglossa with denser but fewer setae on dorsal surface; first segment of palp with thick setae on margins, second segment with setae on outer margin, apical segment with thick and fine setae on margin and surface, those near apex of apical segment gathered into small tufts; segment 1 length subequal to segment 2 length, segment 3 length 0.7 times segment 2 length (Fig. 7).</p> <p>Pronotum light yellow-brown with diffuse black markings medially. Meso- and metanota yellow-brown tinged with dark brown or black laterally. Legs pale; each femur with a dark brown spot at middle and near apex; femora with thick and thin setae on outer margin; tibiae with fine and thick setae on inner margin, and very sparse and thin setae on inner margin, and very sparse and thin setae on outer margin, but hind tibiae mixed with more denser thick and few feathered setae on surface; tarsi of all legs with several thin setae on inner margin and sparse setae on outer margins (Figs 8–10). Claw apically hooked with a row of 4–5 denticles, progressively larger apically (Fig. 11).</p> <p>Abdominal terga 1–10 light yellow-brown with diffuse black markings; terga 1–10 with posterior marginal spines; posterolateral margins of abdominal terga with pointed denticles, size of denticles increases from tergum 6 to tergum 9. Gills on segments 1–7; gill 1 single, slender, lanceolate (Fig. 12); gills 2–7 alike, well-tracheated, upper and lower lamellae of gills 2–7 with 3 apical processes, median process relatively long and other relatively short (Figs 13–16). Sternum 9 of male with deep apical cleft, sternum 9 of female with apex entire and without emargination. Caudal filaments pale yellow-brown; with a whorl of setae on alternate segments; setae shorter than length of corresponding segment.</p> <p> <b>Adult.</b> Unknown.</p> <p> <b>Etymology.</b> The species name “ <i>kaegies</i> ” (pronounced as KGS) is abbreviated patronym of Prof. K.G. Sivaramakrishnan who has significantly contributed to Ephemeroptera taxonomy in India. He is popularly known among his peers, friends and students as “KGS” and hence the species name.</p> <p> <b>Distribution.</b> India (Meghalaya and Himachal Pradesh).</p> <p> <b>Diagnosis.</b> <i>Choroterpes</i> (<i>C.</i>) <i>kaegies</i> Selvakumar, Subramanian & Chandra <b>sp. n.</b> can be distinguished from all known species of <i>Choroterpes</i> (<i>C.</i>) by the following characters: (i) anteromedian emargination of labrum broad (Fig. 2); (ii) each femur with a dark brown spot at middle and near apex (Figs 8–10); (iii) gill 1 single and slender (Fig. 12) and (iv) upper and lower lamellae of gills 2–7 with 3 apical processes, median process relatively slender and longer than laterals (Figs 13–16).</p> <p> <b>Discussion.</b> In India, only two species are recorded from the subgenus <i>Choroterpes</i> s. str. <i>viz</i>., <i>Choroterpes</i> (<i>C.</i>) <i>petersi</i> Tong and Dudgeon, 2003 from southern Western Ghats by Selvakumar <i>et al.</i> (2015) which was originally described from Hong Kong and the present new species, <i>Choroterpes</i> (<i>C.</i>) <i>kaegies</i> Selvakumar, Subramanian & Chandra <b>sp. n.</b> from Himachal Pradesh and Meghalaya. The distribution of <i>Choroterpes</i> (<i>C.</i>) <i>petersi</i> Tong and Dudgeon, 2003 appears to be disjunct in its geographical range. However, <i>Choroterpes</i> (<i>C.</i>) <i>kaegies</i> Selvakumar, Subramanian & Chandra <b>sp. n.</b> is probably widely distributed in Himalaya as the collection localities from two states are geographically widely separated. However, detailed surveys are required. In future detailed morphosystematics and molecular phylogenetic studies are required to fine-tune the subgeneric relationships within the genus <i>Choroterpes</i> Eaton, 1881.</p>Published as part of <i>Selvakumar, C., Subramanian, K. A., Chandra, Kailash & Jehamalar, E. Eyarin, 2017, A new species of Choroterpes Eaton, 1881 (Ephemeroptera: Leptophlebiidae) from India, pp. 189-194 in Zootaxa 4338 (1)</i> on pages 190-193, DOI: 10.11646/zootaxa.4338.1.12, <a href="http://zenodo.org/record/1035542">http://zenodo.org/record/1035542</a&gt

Leptophlebiidae

Key to known genera of south Indian Leptophlebiidae (Larva) <p> 1. Abdominal tergites extending round to ventral surface of the abdomen on segments 3–7, slender gills arise ventrally.................................................................................................... <i>Isca</i> (<i>Isca</i>)</p> <p>- Abdominal tergites extend to lateral margins of the body; gills arise laterally.......................................2</p> <p> 2. Gills present on abdominal segments 1–6.......................................................... <i>Notophlebia</i></p> <p>- Gills present on abdominal segments 1–7...................................................................3</p> <p>3. Middle abdominal gills (3–5) with a fringed margin or with filamentous processes..................................4</p> <p>- Middle abdominal gills not as above.......................................................................5</p> <p> 4. Middle abdominal gills plate like, broadly oval, entire margins fringed with filamentous processes............... <i>Thraulus</i></p> <p> - Middle abdominal gills plate- like, irregular in shape, unevenly fringed with rather broad filamentous processes.... <i>Petersula</i></p> <p> 5. Middle abdominal gills leaf-like; apex of gills 1–7 with three filamentous processes, the median process longer than the lateral processes.................................................................................... <i>Nathanella</i></p> <p>- Middle abdominal gills plate like; apex of gills not as above....................................................6</p> <p>6. Lamellae of gills 2–7 trifurcate...........................................................................7</p> <p>- Lamellae of gills 2–7 not trifurcate........................................................................ 9</p> <p> 7. Gills 1–7 monolamellate....................................................... <i>Choroterpes</i> (<i>Monochoroterpes</i>)</p> <p>- Gills 1–7 bilamellate...................................................................................8</p> <p> 8. Middle abdominal gills terminated in 3 slender, subequal processes........................ <i>..</i> <i>Choroterpes</i> (<i>Euthraulus</i>)</p> <p> - Middle abdominal gills terminated in 3 processes, with median projection longer than laterals.... <i>Choroterpes</i> (<i>Choroterpes</i>)</p> <p> 9. Denticles on claws progressively larger apically; apical denticle much larger............................. <i>Edmundsula</i></p> <p>- Denticles on claws progressively larger apically; apical denticle not much larger...................................10</p> <p> 10. Gills 1–7 similar, dorsal and ventral portions of lamellae slender, tracheae branched............................ <i>Indialis</i></p> <p> - Gills 1–7 dissimilar; dorsal and ventral portions of lamellae of gill 1 slender and lanceolate with branched trachea, dorsal and ventral portions of lamellae of gills 2–7 wider and lanceolate and tapering near apex................ <i>Klugephlebia</i> <b>gen. n.</b></p>Published as part of <i>Selvakumar, C., Sivaruban, T., Subramanian, K. A. & Sivaramakrishnan, K. G., 2016, A new genus and species of Atalophlebiinae (Insecta: Ephemeroptera: Leptophlebiidae) from Palni hills of the southern Western Ghats, India, pp. 381-391 in Zootaxa 4208 (4)</i> on pages 383-384, DOI: <a href="http://zenodo.org/record/208362">10.5281/zenodo.208362</a&gt