1,183 research outputs found

    Efficient Quantum Mixed-State Tomography with Unsupervised Tensor Network Machine Learning

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    Quantum state tomography (QST) is plagued by the ``curse of dimensionality'' due to the exponentially-scaled complexity in measurement and data post-processing. Efficient QST schemes for large-scale mixed states are currently missing. In this work, we propose an efficient and robust mixed-state tomography scheme based on the locally purified state ansatz. We demonstrate the efficiency and robustness of our scheme on various randomly initiated states with different purities. High tomography fidelity is achieved with much smaller numbers of positive-operator-valued measurement (POVM) bases than the conventional least-square (LS) method. On the superconducting quantum experimental circuit [Phys. Rev. Lett. 119, 180511 (2017)], our scheme accurately reconstructs the Greenberger-Horne-Zeilinger (GHZ) state and exhibits robustness to experimental noises. Specifically, we achieve the fidelity F0.92F \simeq 0.92 for the 10-qubit GHZ state with just Nm=500N_m = 500 POVM bases, which far outperforms the fidelity F0.85F \simeq 0.85 by the LS method using the full Nm=310=59049N_m = 3^{10} = 59049 bases. Our work reveals the prospects of applying tensor network state ansatz and the machine learning approaches for efficient QST of many-body states.Comment: 7 pages, 6 figure

    Sampling Neural Radiance Fields for Refractive Objects

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    Recently, differentiable volume rendering in neural radiance fields (NeRF) has gained a lot of popularity, and its variants have attained many impressive results. However, existing methods usually assume the scene is a homogeneous volume so that a ray is cast along the straight path. In this work, the scene is instead a heterogeneous volume with a piecewise-constant refractive index, where the path will be curved if it intersects the different refractive indices. For novel view synthesis of refractive objects, our NeRF-based framework aims to optimize the radiance fields of bounded volume and boundary from multi-view posed images with refractive object silhouettes. To tackle this challenging problem, the refractive index of a scene is reconstructed from silhouettes. Given the refractive index, we extend the stratified and hierarchical sampling techniques in NeRF to allow drawing samples along a curved path tracked by the Eikonal equation. The results indicate that our framework outperforms the state-of-the-art method both quantitatively and qualitatively, demonstrating better performance on the perceptual similarity metric and an apparent improvement in the rendering quality on several synthetic and real scenes.Comment: SIGGRAPH Asia 2022 Technical Communications. 4 pages, 4 figures, 1 table. Project: https://alexkeroro86.github.io/SampleNeRFRO/ Code: https://github.com/alexkeroro86/SampleNeRFR

    CXCR4 Antagonist AMD3100 Modulates Claudin Expression and Intestinal Barrier Function in Experimental Colitis

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    Ulcerative colitis is a gastrointestinal disorder characterized by local inflammation and impaired epithelial barrier. Previous studies demonstrated that CXC chemokine receptor 4 (CXCR4) antagonists could reduce colonic inflammation and mucosal damage in dextran sulfate sodium (DSS)-induced colitis. Whether CXCR4 antagonist has action on intestinal barrier and the possible mechanism, is largely undefined. In the present study, the experimental colitis was induced by administration of 5% DSS for 7 days, and CXCR4 antagonist AMD3100 was administered intraperitoneally once daily during the study period. For in vitro study, HT-29/B6 colonic cells were treated with cytokines or AMD3100 for 24 h until assay. DSS-induced colitis was characterized by morphologic changes in mice. In AMD3100-treated mice, epithelial destruction, inflammatory infiltration, and submucosal edema were markedly reduced, and the disease activity index was also significantly decreased. Increased intestinal permeability in DSS-induced colitis was also significantly reduced by AMD3100. The expressions of colonic claudin-1, claudin-3, claudin-5, claudin-7 and claudin-8 were markedly decreased after DSS administration, whereas colonic claudin-2 expression was significantly decreased. Treatment with AMD3100 prevented all these changes. However, AMD3100 had no influence on claudin-3, claudin-5, claudin-7 and claudin-8 expression in HT-29/B6 cells. Cytokines as TNF-α, IL-6, and IFN-γ increased apoptosis and monolayer permeability, inhibited the wound-healing and the claudin-3, claudin-7 and claudin-8 expression in HT-29/B6 cells. We suggest that AMD3100 acted on colonic claudin expression and intestinal barrier function, at least partly, in a cytokine-dependent pathway

    Control of the dipole layer of polar organic molecules adsorbed on metal surfaces via different charge-transfer channels

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    Organic molecules with a permanent electric dipole moment have been widely used as a template for further growth of molecular layers in device structures. Key properties of the resulting organic films such as energy level alignment (ELA), work function, and injection/collection barrier are linked to the magnitude and direction of the dipole moment at the interface. Using angle-resolved photoemission spectroscopy (ARPES), we have systematically investigated the coverage-dependent work function and spectral line shapes of occupied molecular energy states (MES) of chloroaluminium-phthalocyanine (ClAlPc) grown on Ag(111). We demonstrate that the dipole orientation of the first ClAlPc layer can be controlled by adjusting the deposition rate and post annealing conditions; the ELA at the interface differs by ~0.4 eV between the Cl-up and -down configurations of the adsorbed ClAlPc molecules. These observations are rationalized by density-functional-theory (DFT) calculations based on a realistic model of the ClAlPc/Ag(111) interface, which reveal that the different orientations of the ClAlPc dipole layer lead to different charge-transfer channels between the adsorbed ClAlPc and Ag(111) substrate. Our findings provide a useful framework towards method development for ELA tuning

    Postchallenge responses of nitrotyrosine and TNF-alpha during 75-g oral glucose tolerance test are associated with the presence of coronary artery diseases in patients with prediabetes

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    <p>Abstract</p> <p>Background</p> <p>Meta-analysis has demonstrated an exponential relationship between 2-hr postchallenge hyperglycemia and coronary artery disease (CAD). Pulsatile hyperglycemia can acutely increase proinflammatory cytokines by oxidative stress. We hypothesized that postchallenge proinflammatory and nitrosative responses after 75 g oral glucose tolerance tests (75 g-OGTT) might be associated with CAD in patients without previously recognized type 2 diabetes mellitus (T2DM).</p> <p>Methods</p> <p>Serial changes of plasma glucose (PG), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and nitrotyrosine levels were analyzed during 75 g-OGTT in 120 patients (81 male; age 62 ± 11 years) before coronary angiography. Patients were classified as normal (NGT; 42%), impaired (IGT; 34%) and diabetic (T2DM; 24%) glucose tolerance by 75 g-OGTT.</p> <p>Results</p> <p>Postchallenge hyperglycemia elicited TNF-α, IL-6 and nitrotyrosine levels time-dependently, and 2-hr median levels of TNF-α (7.1 versus 6.4 pg/ml; <it>P </it>< 0.05) and nitrotyrosine (1.01 versus 0.83 <it>μ</it>mol/l; <it>P </it>< 0.05), but not IL-6 or PG, were significantly higher in patients with CAD in either IGT or T2DM groups. After adjusting risk factors and glucose tolerance status, 2-hr nitrotyrosine in highest quartiles (OR: 3.1, <it>P </it>< 0.05) remained an independent predictor of CAD by logistic regression analysis.</p> <p>Conclusions</p> <p>These results highlight postchallenge proinflammatory and nitrosative responses by 75 g-OGTT, rather than hyperglycemia <it>per se</it>, are associated with CAD in patients without previous recognized diabetes.</p

    Edge states in Open Antiferromagnetic Heisenberg Chains

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    In this letter we report our results in investigating edge effects of open antiferromagnetic Heisenberg spin chains with spin magnitudes S=1/2,1,3/2,2S=1/2, 1,3/2,2 using the density-matrix renormalization group (DMRG) method initiated by White. For integer spin chains, we find that edge states with spin magnitude Sedge=S/2S_{edge}=S/2 exist, in agreement with Valence-Bond-Solid model picture. For half-integer spin chains, we find that no edge states exist for S=1/2S=1/2 spin chain, but edge state exists in S=3/2S=3/2 spin chain with Sedge=1/2S_{edge}=1/2, in agreement with previous conjecture by Ng. Strong finite size effects associated with spin dimmerization in half-integer spin chains will also be discussed.Comment: 4 pages, RevTeX 3.0, 5 figures in a separate uuencoded postscript file. Replaced once to enlarge the acknowlegement
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