6 research outputs found

    Effect of perchlorate and thiocyanate exposure on thyroid function of pregnant women from South-West England: a cohort study

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    This article is freely available via Open Access. Click on the Additional Link above to access the full-text via the publisher's site

    A novel ESR2 frameshift mutation predisposes to medullary thyroid carcinoma and causes inappropriate RET expression

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    Maternal thyroid function in pregnant women with a breech presentation in late gestation.

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    Breech presentation occurs in 3-5% of all full-term pregnancies, and is associated with obstetric complications. The known risk factors for breech presentation include prematurity, low birth-weight, multiple pregnancy, primiparity, polyhydramnios or oligohydramnios, fetal anomalies (e.g. placenta praevia, hydrocephaly or anencephaly) and uterine abnormalities (e.g. septate/bicornuate uterus). A study from the Netherlands has suggested that maternal thyroid hormone deficiency during late pregnancy is also a risk factor.(1) In this cohort study of 1058 pregnant women, 58 women with breech presentation had higher serum TSH at 36 weeks gestation than those with cephalic presentation, and TSH level ≥2.5mIU/L at 36 weeks gestation was associated with over a two-fold higher risk of breech presentation. This article is protected by copyright. All rights reserved

    Iodine deficiency amongst pregnant women in South-West England.

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    Iodine deficiency in pregnancy may impair foetal neurological development. The UK population is generally thought to be iodine sufficient; however recent studies have questioned this assumption. Our study aimed to explore the prevalence of iodine deficiency in a cohort of pregnant mothers from South-West England
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