Chemical Composition and Biological Activities of Leaves Essential Oil From Schinus molle (Anacardiaceae)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)The essential oil of Schinus molle (Anacardiaceae) obtained by hydrodistillation from the aerial parts, was analyzed by gas chromatography (GC), GC-mass spectrometry (MS) and nuclear magnetic resonance (NMR). The oil contains 69.1 % of sesquiterpenes and 20% of monoterpenes. The most abundant essential oil components were 1,8-cineole (7.6 %), terpin-4-ol (6.1 %), epi-alpha-cadinol (27.3 %), caryophyllene oxide (10.5 %), gamma-cadinene (9.1 %), spathulenol (8.6 %), 1,10-di-epi-cubenol (4.4 %) and 7-epi-alpha-eudesmol (2.3 %). The leaf essential oil showed pronounced in-vitro cytotoxic activity against K562 (0.89 mu g/mL) and NCI-ADR/RES (3.40 mu g/mL) human tumor cell lines. The antimicrobial, antioxidant and allelophathic activities of essential oil were also evaluated.145590599Fundacao de Apoio ao Desenvolvimento de EnsinoCiencia e Tecnologia de Mato Grosso do Sul (FUNDECT-MS)UFMSConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)DCRConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq