Single Plasma Concentrations of 1′‐Hydroxymidazolam or the Ratio of 1′‐Hydroxymidazolam: Midazolam Do Not Predict Midazolam Clearance in Healthy Subjects

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97152/1/009127002237986.pd

Limited Sampling Strategy to Predict AUC of the CYP3A Phenotyping Probe Midazolam in Adults: Application to Various Assay Techniques

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97211/1/00912700222011418.pd

The James Webb Space Telescope Mission

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

Interaction Study between Digoxin and a Preparation of Hawthorn ( Crataegus oxyacantha )

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97293/1/0091270003253417.pd

Case Notes

Administrative Law - Justiciable Controversy - Rights to Injunctive Relief from Communistic Listing by Attorney General (Joint Anti-Fascist Refugee Committee v. McGrath, U .S. 1951) Insurance - Exclusionary Clause - Construction of Term Possession (McDowell Motor Co. v. N. Y. Underwriters Ins. Co., N.C. 1951) Municipal Corporations - Liability for Negligence - Injury to Prisoner on Street Project (City of Atlanta v. Hurley, Ga. 1951) Partnerships - Joint Adventures - Intent Necessary to Constitute Joint Adventure (Lilly v. Munsey, W .Va. 1951) Practice and Procedure - Declaratory Judgments - Supreme Court Jurisdiction in Cases Not Involving Title to Land or Equitable Relief (Bond v. Ray, Ga. 1951 ) Torts - Legislative Immunity - Investigating Committees (Tenney v. Brandhove, U.S. 1951) Trade Regulation - Price Fixing - Non-Signer Provision in State Fair Trade Act (Schwegmann Brothers v. Calvert Distillers Corp., U.S. 1951) Wills - Adoption - Revocation of Previously Made Will By Adoption of Child (Thornton v. Anderson, Ga. 1951) Wills - Construction - Income Tax Liability on Bequests (In re Nevil\u27s Estate, Pa. 1951) Wills - Disposition of Property by Life Tenant Under Power of Appointment (Blanks v. Jiggetts, Va. 1951