24,839 research outputs found
Technology-enhanced learning: evidence-based improvement
The design of learning materials and researching their efficacy involves the application of both theoretical learning principles and ways of working or practices to move towards evidence based improvement. This paper abstracts 4 categories from our on-going work of educational technology research which we have found to be important in considering what constitutes a successful Technology-Enhanced Learning implementation. These considerations influence the likelihood or feasibility of the wider adoption a particular Technology-Enhanced Learning implementation in the longer term. We also discuss how these considerations relate to the scalability of the development
Super-resolution imaging and estimation of protein copy numbers at single synapses with DNA-PAINT
In the brain, the strength of each individual synapse is defined by the complement of proteins present or the "local proteome." Activity-dependent changes in synaptic strength are the result of changes in this local proteome and posttranslational protein modifications. Although most synaptic proteins have been identified, we still know little about protein copy numbers in individual synapses and variations between synapses. We use DNA-point accumulation for imaging in nanoscale topography as a single-molecule super-resolution imaging technique to visualize and quantify protein copy numbers in single synapses. The imaging technique provides near-molecular spatial resolution, is unaffected by photobleaching, enables imaging of large field of views, and provides quantitative molecular information. We demonstrate these benefits by accessing copy numbers of surface AMPA-type receptors at single synapses of rat hippocampal neurons along dendritic segments
MST Resistive Wall Tearing Mode Simulations
The Madison Symmetric Torus (MST) is a toroidal device that, when operated as
a tokamak, is resistant to disruptions. Unlike most tokamaks, the MST plasma is
surrounded by a close fitting highly conducting wall, with a resistive wall
penetration time two orders of magnitude longer than in JET or DIII-D, and
three times longer than in ITER. The MST can operate with edge q_a < 2, unlike
standard tokamaks. Simulations presented here indicate that the MST is unstable
to resistive wall tearing modes (RWTMs) and resistive wall modes (RWMs). They
could in principle cause disruptions, but the predicted thermal quench time is
much longer than the experimental pulse time. If the MST thermal quench time
were comparable to measurements in JET and DIII-D, theory and simulations
predict that disruptions would have been observed in MST. This is consistent
with the modeling herein, predicting that disruptions are caused by RWTMs and
RWMs. In the low q_a regime of MST, the RWTM asymptotically satisfies the RWM
dispersion relation. The transition from RWTM to RWM occurs smoothly at q_a =
m/n, where m,n are poloidal and toroidal mode numbers
Optimal irrigation management strategies under weather uncertainty and risk
Climate change will affect agricultural production through changes in water supply, such that optimal irrigation management strategies gain importance. For the Marchfeld region, we firstly analyze with a stochastic dynamic programming approach the probability of investing into either a water-saving drip or a sprinkler irrigation system until 2040. Secondly, we develop optimal irrigation management portfolios for different degrees of risk aversion using climate data from a statistical model and the simulations for specific crops of the biophysical process model EPIC (Environmental Policy Integrated Climate). Investment in drip irrigation systems is not profitable. Sprinkler irrigation has a positive probability of being adopted for the production of sugar beets and carrots and therefore mostly shows a 100% share in the portfolio optimization
Mythical Thinking, Scientific Discourses and Research Dissemination
This article focuses on some principles for understanding. By taking Anna Mikulakâs article âMismatches between âscientificâ and ânon-scientificâ ways of knowing and their contributions to public understanding of scienceâ (IPBS 2011) as a point of departure, the idea of demarcation criteria for scientific and non-scientific discourses is addressed. Yet this is juxtaposed with mythical thinking, which is supposed to be the most salient trait of non-scientific discourses. The author demonstrates how the most widespread demarcation criterion, the criterion of verification, is self-contradictory, not only when it comes to logic, but also in the achievement of isolating natural sciences from other forms of knowledge. According to Aristotle induction is a rhetorical device and as far as scientific statements are based on inductive inferences, they are relying on humanities, which rhetoric is a part of. Yet induction also has an empirical component by being based on sense-impressions, which is not a part of the rhetoric, but the psychology. Also the myths are understood in a rhetorical (LĂ©vi-Strauss) and a psychological (Cassirer) perspective. Thus it is argued that both scientific and non-scientific discourses can be mythical
The Sloan Digital Sky Survey Reverberation Mapping Project: Post-Starburst Signatures in Quasar Host Galaxies at z < 1
Quasar host galaxies are key for understanding the relation between galaxies
and the supermassive black holes (SMBHs) at their centers. We present a study
of 191 broad-line quasars and their host galaxies at z < 1, using high
signal-to-noise ratio (SNR) spectra produced by the Sloan Digital Sky Survey
Reverberation Mapping project. Clear detection of stellar absorption lines
allows a reliable decomposition of the observed spectra into nuclear and host
components, using spectral models of quasar and stellar radiations as well as
emission lines from the interstellar medium. We estimate age, mass (M*), and
velocity dispersion (sigma*) of the host stars, the star formation rate (SFR),
quasar luminosity, and SMBH mass (Mbh), for each object. The quasars are
preferentially hosted by massive galaxies with M* ~ 10^{11} Msun characterized
by stellar ages around a billion years, which coincides with the transition
phase of normal galaxies from the blue cloud to the red sequence. The host
galaxies have relatively low SFRs and fall below the main sequence of
star-forming galaxies at similar redshifts. These facts suggest that the hosts
have experienced an episode of major star formation sometime in the past
billion years, which was subsequently quenched or suppressed. The derived Mbh -
sigma* and Mbh - M* relations agree with our past measurements and are
consistent with no evolution from the local Universe. The present analysis
demonstrates that reliable measurements of stellar properties of quasar host
galaxies are possible with high-SNR fiber spectra, which will be acquired in
large numbers with future powerful instruments such as the Subaru Prime Focus
Spectrograph.Comment: ApJ in pres
Representation of Quantum Mechanical Resonances in the Lax-Phillips Hilbert Space
We discuss the quantum Lax-Phillips theory of scattering and unstable
systems. In this framework, the decay of an unstable system is described by a
semigroup. The spectrum of the generator of the semigroup corresponds to the
singularities of the Lax-Phillips -matrix. In the case of discrete (complex)
spectrum of the generator of the semigroup, associated with resonances, the
decay law is exactly exponential. The states corresponding to these resonances
(eigenfunctions of the generator of the semigroup) lie in the Lax-Phillips
Hilbert space, and therefore all physical properties of the resonant states can
be computed.
We show that the Lax-Phillips -matrix is unitarily related to the
-matrix of standard scattering theory by a unitary transformation
parametrized by the spectral variable of the Lax-Phillips theory.
Analytic continuation in has some of the properties of a method
developed some time ago for application to dilation analytic potentials.
We work out an illustrative example using a Lee-Friedrichs model for the
underlying dynamical system.Comment: Plain TeX, 26 pages. Minor revision
A Study of Lyman-Alpha Quasar Absorbers in the Nearby Universe
Spectroscopy of ten quasars obtained with the Goddard High Resolution
Spectrograph (GHRS) of the Hubble Space Telescope (HST) is presented. A
clustering analysis reveals an excess of nearest neighbor line pairs on
velocity scales of 250-750 km/s at a 95-98% confidence level. The hypothesis
that the absorbers are randomly distributed in velocity space can be ruled out
at the 99.8% confidence level. No two-point correlation power is detected (xi <
1 with 95% confidence). Lyman-alpha absorbers have correlation amplitudes on
scales of 250-500 km/s at least 4-5 times smaller than the correlation
amplitude of bright galaxies. A detailed comparison between absorbers in nearby
galaxies is carried out on a limited subset of 11 Lyman- alpha absorbers where
the galaxy sample in a large contiguous volume is complete to M_B = -16.
Absorbers lie preferentially in regions of intermediate galaxy density but it
is often not possible to uniquely assign a galaxy counterpart to an absorber.
This sample provides no explicit support for the hypothesis that absorbers are
preferentially associated with the halos of luminous galaxies. We have made a
preliminary comparison of the absorption line properties and environments with
the results of hydrodynamic simulations. The results suggest that the
Lyman-alpha absorbers represent diffuse or shocked gas in the IGM that traces
the cosmic web of large scale structure. (abridged)Comment: 36 pages of text, 15 figures, 4 tables, 36 file
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