An Examination of Culturally Competent Transformational Leadership Influence of Student Achievement and Stake-holders Perception

This research consists of a non-experimental, descriptive and correlation research design to analyze the relationship between principals’ leadership style as well as principal cultural competency and their impact on student achievement and stake-holders perception. The study took place in the South Puget Sound region of Washington state in one of the fastest growing areas in the U.S. The researcher investigated the impact of transformational leadership in education based on research that posited that transformational leaders inspired and motivated followers to exceed performance expectation and commitment to a shared goal (Bass, 1985a; Burns, 1978;). The study relied heavily on prior educational studies that indicated that transformation leadership was the most effective and successful leadership model for school reform and school improvement. The study also investigated education leaders’ culturally competency and the significance of the appreciating individuals’ communities, ethnic cultures and family traditions to provide optimal educational experiences (Arthur et al, 2005). The study investigated the overall impact of school leadership through the lens of concurrent use of transformational leadership and culturally competent leadership and their influence of student academic achievement and stake-holders perception. The study concluded with practical implication for a proposal for a new leadership framework titled, The Diverse School Leadership

Rethinking feline coronavirus infection outcomes

This article outlines the parallels between feline infectious peritonitis (FIP) and COVID-19. The effect of SARS-Cov-2 on the human vascular system are only starting to be understood. From cardiac complications and COVID toes in adults, to multisystem inflammatory syndrome in children (MIS-C), the world of human medicine is tackling some of the more perplexing and severe complications of SARS-2 in real time. Dr. Alison Stout and her colleagues at the Whittaker Lab share insights learned from years studying FIP and make a compelling argument for a one-health approach to the global pandemic

Pretargeted Positron Emission Tomography Imaging That Employs Supramolecular Nanoparticles with in Vivo Bioorthogonal Chemistry

A pretargeted oncologic positron emission tomography (PET) imaging that leverages the power of supramolecular nanoparticles with in vivo bioorthogonal chemistry was demonstrated for the clinically relevant problem of tumor imaging. The advantages of this approach are that (i) the pharmacokinetics (PKs) of tumor-targeting and imaging agents can be independently altered via chemical alteration to achieve the desired in vivo performance and (ii) the interplay between the two PKs and other controllable variables confers a second layer of control toward improved PET imaging. In brief, we utilized supramolecular chemistry to synthesize tumor-targeting nanoparticles containing transcyclooctene (TCO, a bioorthogonal reactive motif), called TCO⊂SNPs. After the intravenous injection and subsequent concentration of the TCO⊂SNPs in the tumors of living mice, a small molecule containing both the complementary bioorthogonal motif (tetrazine, Tz) and a positron-emitting radioisotope ((64)Cu) was injected to react selectively and irreversibly to TCO. High-contrast PET imaging of the tumor mass was accomplished after the rapid clearance of the unreacted (64)Cu-Tz probe. Our nanoparticle approach encompasses a wider gamut of tumor types due to the use of EPR effects, which is a universal phenomenon for most solid tumors