High variability of iodine in iodized salt and urine from rural households in Sidama zone, Southern Ethiopia: A cross-sectional study.

Iodine is essential for the synthesis of thyroid hormones which regulate the metabolic processes of most cells and play important roles in human growth and development. Iodine deficiency has long been one of the most common nutritional problems in the world. Ethiopia, particularly the study population (Sidama) has a history of severe iodine deficiency. The purpose of the study was to assess urinary iodine concentration, level of goiter in mothers and school-age children and household salt iodine concentration in households 10 months after launch of the national salt iodization program. A cross-sectional study was conducted on a randomly selected sample of women and schoolchildren. Goiter was assessed by palpation. Concentrations of iodine in salt, urine and water were analyzed by inductively coupled plasma mass spectrometry (ICP-MS).The study included 193 mothers and 76children. The median (IQR) urinary iodine concentration (UIC) was 143 (84, 202) μg/L in the mothers and 187 (102, 278) μg/L in the children. Mothers’ UIC ranged from 17 to 767.2 μg/L and children’s UIC ranged from 19 to 739 μg/L. Goiter prevalence was high in both mothers (76%) and children (79%). The median household salt iodine concentration (SIC) was 8.1 (4.3, 13.4) ppm (mg/kg) with a range of 0 to 42 ppm. None of the water samples contained iodine above the detection limit of 1 μg/L. Despite the launchof the salt iodization program in Ethiopia, 94% of the study participants were not aware that they used iodized salt and 88% did not know the benefits of iodized salt. The major source of iodine for this population was iodized salt; however, the salt at household level contained minimal but variable amounts of iodine.Low concentration of iodine in salt may be further compounded by storage, handling and cooking techniques.The high variability of salt iodine concentration (SIC) was also reflected in the UIC of the mothers and children

Chronic inflammation was a major predictor and determinant factor of anemia in lactating women in Sidama zone southern Ethiopia: A cross-sectional study

Anemia in women of reproductive age is highly prevalent globally and remains a public health problem. In Ethiopia, despite efforts to minimize the burden of anemia, it is still a moderate public health problem. Anemia has various etiologies including nutritional deficiency, parasitic infection, and inflammation. The aim of this study was to examine contributing factors to anemia in lactating women. Following ethical approval, and six months after delivery, all lactating women (n = 150) were recruited to participate in this study from eight randomly selected rural villages. Anthropometric and socio-economic factors were assessed. From each, a blood sample was collected for measuring hemoglobin, iron biomarkers, zinc, selenium, and inflammation markers. The median (IQR) hemoglobin (Hb) was 132 (123, 139) g/L. Of the women, 19% were anemic and 7% had iron deficiency anemia; 31% were iron deficient and 2% had iron overload. Also, 8% had functional iron deficit, 6% had acute inflammation, 13% had chronic inflammation, and 16% had tissue iron deficiency. The majority (78%) of the women had low plasma zinc out of which more than 16% were anemic. Hb was positively associated with plasma iron and plasma zinc and negatively associated with transferrin receptor (TfR) and α-1-acid glycoprotein (AGP). Plasma iron, AGP, TfR, hepcidin and plasma zinc were significant predictors of maternal anemia. Additionally MUAC and level of education were associated positively with maternal hemoglobin. This study showed that maternal anemia was associated with multiple factors including nutritional deficiencies, inflammation and limited education

Challenges and opportunities to the African agriculture and food systems

Reduction in the proportion of undernourished people worldwide has been achieved despite global population increase. However, the achievement of reducing undernourishment globally was uneven; sub-Saharan Africa (SSA) in particular has the least progress. In SSA, agriculture is only slowly changing with actual well below potential yields. Failures in agricultural policies, weak institutions, and poor governance are the root of growth stagnation. Agriculture contributes a significant share to the SSA economy and a majority of the population derives their livelihood from this sector. It is justifiable to assume that for sustainable growth of the African economy, significant investment and creative innovation in agriculture are needed. However, several factors such as growth of the farming population, loss of soil fertility, climate change, water scarcity, post-harvest losses, and limited market access could challenge such expectation. On the other hand, new policy reforms and initiatives, and appropriate investment that directly or indirectly support agricultural innovation and growth are emerging. This chapter discusses the challenges and opportunities to advance agricultural growth and food systems in Africa and makes recommendations for solutions.Keywords: Africa, food systems, agriculture, agricultural research, agricultural investmen

Using a Mobile Food Pantry to Address the Food Insecurity Needs of College Students

Food insecurity is a prevalent issue throughout the United States, the state of Oklahoma, and on Oklahoma State University’s (OSU) Stillwater campus. Research has shown that college and university students tend to be more food insecure than national population averages and Stillwater’s food insecurity rates have been even higher. Mobile food pantries (MFP) generally have been effective in addressing food insecurity, but few studies have investigated their use to alleviate food insecurity among college students. Our Daily Bread Food and Resource Center (ODB) in Stillwater implemented an MFP on OSU’s campus. The present study surveyed students who utilized the MFP to assess their needs, food security status, and perceptions of the MFP. Of 130 students who answered the food security questions (after receiving their food), more than 83% were classified as food insecure. Respondents agreed that the MFP provided sufficient foods considering nutritional value, variety, diversity, and acceptability. Students were mostly unaware of available food assistance programs but were open to using them. Almost one-third of students reported no grocery or market within walking distance of their residence. Overall, the findings of this study showed a need for an MFP on OSU’s campus

Excessive intake of iodine and low prevalence of goiter in school age children five years after implementation of national salt iodization in Shebedino woreda, southern Ethiopia

Background Iodine is a trace element required for the synthesis of thyroid hormones. The multiple effects of iodine deficiency on human health are called iodine deficiency disorders (IDDs). IDDs have been common nutritional problems in Ethiopia. In 2012, Ethiopia launched a national salt iodization program to address IDDs. The objective of this study was to assess the effects of this program after 5 years by measuring urinary iodine concentration (UIC) and prevalence of goiter in school age children as well as household salt iodine concentration (SIC). Methods A school-based cross-sectional design was employed. After ethical approval, 408 children from eight randomly selected primary schools provided urine samples. UIC was analyzed by inductively coupled plasma mass spectrophotometry (ICP-MS). A 10 g salt sample was collected from each household of a sampled child. SIC was analyzed with a digital electronic iodine checker (WYD, UNICEF) and goiter was assessed by palpation. Results The mean (±SD) age of the children was 9 ± 2 years. The prevalence of goiter was 4.2% and no child had grade 2 goiter. The median (IQR) UIC was 518 (327, 704) μg/L and UIC ranged from 3.1 to 2530 μg/L. Of the salt samples, 15.6% were not adequately iodized (\u3c 15 ppm), 39.3% were adequately iodized (≥15 to ≤40 ppm), and 45.1% were \u3e 40 ppm. SIC ranged from 4.2 to 195 ppm. Of the mothers, 92% said iodized salt prevents goiter and 8% mentioned prevents mental retardation. Conclusions In 2017 iodine deficiency was no longer a public health problem in the study area. However, the high variability in UIC and SIC and excessive iodine intake are of great concern. It is vital to ensure that salt is homogenously iodized at the production site before being distributed to consumers

Nutritive value and sensory acceptability of corn- and kocho- based foods supplemented with legumes for infant feeding in Southern Ethiopia

In most developing countries, complementary foods are based on staple cereal or root crops. Imported or commercially developed foods generally are not used by low-income rural households due to high cost and poor availability. To improve the quality of children's diets in Southern Ethiopia, two complementary foods were formulated based on corn, or on an indigenous root crop (Enset ventricosum) product called kocho. Kidney beans and pumpkin pulp were used to improve the protein and vitamin A values, respectively. Kidney beans and corn were soaked, germinated and lightly roasted before grinding. Four formulations of complementary foods were prepared. Two of them were traditional corn- or kocho-based, and served as controls. The other two were supplemented formulations, and contained either corn:kidney bean:pumpkin (CBP) or kocho:kidney bean:pumpkin (KBP). Crude protein and fat, amino acid profile, and carotene content of the corn, kocho, kidney bean, and pumpkin were determined by standard AOAC methods. The four formulations were evaluated for sensory acceptability in Southern Ethiopia by mother and child pairs. The CBP and KBP formulations had crude protein contents of 14.07 g/100 g and 13.81 g/100 g, respectively, while the traditional corn and kocho had only 8.82 g/100 g and 1.46 g/100 g, on a dry weight basis. Adding kidney beans to both mixtures improved their essential amino acid profiles, but the need to serve the foods as thin porridge for infants created low energy density products. The pumpkin in CBP and KBP provided 54 µg RAE per 100 kcal, increasing the Vitamin A value of the mixes by 25- and 180-fold, respectively. Sensory evaluation of CBP by 30 mother and child pairs, and KBP by 28 pairs indicated high acceptability (4.7 - 4.9 on a 5-pt Hedonic scales) of the complementary foods. Acceptability scores of CBP and KBP were not significantly different (p > 0.05) from those of the traditional corn and kocho formulations. Thus, addition of kidney beans and pumpkin is a potential way to increase the nutritive value of traditional Ethiopian complementary foods prepared from corn or kocho. Keywords: amino acid profile, legume, nutrient density, complementary foods, vitamin A African Journal of Food, Agriculture, Nutrition and Development Vol. 6(1) 200

Iodine supplementation of lactating women and assessment of infant visual information processing and maternal and infant thyroid function: A randomized trial

Iodine deficiency is one of the major causes of brain damage in childhood. However, iodine supplementation during early pregnancy and lactation can prevent the ill effects of iodine deficiency. This study evaluated maternal and infant thyroid function and infant visual information processing (VIP) in the context of maternal iodine supplementation. A community-based, randomized, supplementation trial was conducted. Mother infant dyads (n = 106) were enrolled within the first 10 days after delivery to participate in this study. Mothers were randomly assigned either to receive a potassium iodide capsule (225 μg iodine) daily for 26 weeks or iodized salt weekly for 26 weeks. Maternal thyroxine (T4), triiodothyronine (T3), thyroid stimulating hormone (TSH), thyroglobulin (Tg), urinary iodine concentration (UIC), breast milk iodine concentration (BMIC) and infant T4, TSH, UIC and VIP were measured as outcome variables. At baseline, neither mothers nor infants in the two groups were significantly different in any of the biomarkers or anthropometric measurements. Maternal TSH and goiter prevalence significantly decreased following iodine supplementation. The percentage of infants who preferentially remembered the familiar face was 26% in the capsule and 51% in the I-salt groups. Infant sex, length for age Z score, BMIC, maternal education and household food security were strong predictors of novelty quotient. In conclusion supplementation daily for six months with an iodine capsule or the use of appropriately iodized salt for an equivalent time was sufficient to reduce goiter and TSH in lactating women. Higher BMIC and LAZ as well as better household food security, maternal education, and male sex predicted higher novelty quotient scores in the VIP paradigm

Conical Correlations, Bragg Peaks, and Transverse Flow Deflections in Jet Tomography

We use (3+1)-dimensional ideal hydrodynamics to describe a variety of different jet energy loss scenarios for a jet propagating through an opaque medium. The conical correlations obtained for fully stopped jets, revealing a Bragg peak, are discussed as well as results from pQCD and AdS/CFT. Moreover, we investigate transverse flow deflection. It is demonstrated that a double-peaked away-side structure can be formed due to the different contributions of several possible jet trajectories through an expanding medium.Comment: 4 pages, 3 figures - To appear in the conference proceedings for Quark Matter 2009, March 30 - April 4, Knoxville, Tennessee, revised versio

Factors associated with nutritional status of infants and young children in Somali Region, Ethiopia: a cross- sectional study

Background: Inadequate nutrition during the first two years of life may lead to childhood morbidity and mortality, as well as inadequate brain development. Infants are at increased risk of malnutrition by six months, when breast milk alone is no longer sufficient to meet their nutritional requirements. However the factors associated with nutritional status of infants after 6 months of age have received little attention in pastoralist communities of Ethiopia. Therefore this study aimed to identify the factors associated with nutritional status of infants and young children (6-23 months) in Filtu town, Somali Region, Ethiopia.Methods: A cross-sectional community-based study was conducted. Simple random sampling was employed to select 214 infants for the study. Univariable and multivariable logistic regressions models were used in the statistical analysis. The strength of association was measured by odds ratios with 95 % confidence intervals. Both the crude (COR) and adjusted odds ratios (AOR) are reported.Results: The prevalence of wasting, stunting and underweight among infants and young children were 17.5 % (95 % CI: 12.91-23.22), 22.9 % (95 % CI: 17.6-28.9) and 19.5 % (95 % CI: 14.58-25.3) respectively. The multivariable logistic regression model showed that breastfeeding was independently associated with reduced odds of wasting (AOR = 0.38(95 % CI: 0.14-0.99)). Diarrhea in the past 15 days (AOR = 2.13 (95 % CI: 1.55-4.69)) was also associated with increased odds for wasting. The independent predictors of reduced odds for stunting were dietary diversity score ≥4 (AOR = 0.45(95 % CI: 0.21-0.95)) and introduction of complementary feeding at 6 months (AOR = 0.25 (95 % CI: 0.09-0.66)). Bottle feeding was associated with increased odds of stunting (AOR = 3.83 (95 % CI: 1.69-8.67)). Breastfeeding was associated with reduced odds of underweight (AOR = 0.24 (95 % CI: 0.1-0.59)), while diarrheal disease in the past 15 days was associated with increased odds of underweight (AOR = 3.54 (95 % CI: 1.17-7.72)).Conclusion: Under nutrition is a public health problem among infants and young children in Filtu town, Somali region Ethiopia. Breastfeeding was associated with lower odds of wasting and underweight while diarrheal disease was associated with higher odds of wasting and underweight. Low dietary diversity scores, inappropriate age of complementary feeding initiation and bottle feeding were identified to be significant predictors of stunting. Those factors should be considered for any intervention aimed to reduce under nutrition among infants and young children in Filitu town, Somali region, Ethiopia.Peer reviewedNutritional Science