466 research outputs found
On some invariant ideals, and on extension of differentiations to seminormalization
AbstractLet A be a noetherian integral domain, D=(1,D1,…,Di…) be a differentation of A, and B be a ring such that A⊂B⊂Ā. In the paper we mainly prove (whenever Ā is finite over A): (a) if α is the conductor of A in B, then A√α is D-invariant. (b) D extends to the seminormalization +A of A in Ā
Neural correlates of perceiving emotional faces and bodies in developmental prosopagnosia:An event-related fMRI-study
Many people experience transient difficulties in recognizing faces but only a small number of them cannot recognize their family members when meeting them unexpectedly. Such face blindness is associated with serious problems in everyday life. A better understanding of the neuro-functional basis of impaired face recognition may be achieved by a careful comparison with an equally unique object category and by a adding a more realistic setting involving neutral faces as well facial expressions. We used event-related functional magnetic resonance imaging (fMRI) to investigate the neuro-functional basis of perceiving faces and bodies in three developmental prosopagnosics (DP) and matched healthy controls. Our approach involved materials consisting of neutral faces and bodies as well as faces and bodies expressing fear or happiness. The first main result is that the presence of emotional information has a different effect in the patient vs. the control group in the fusiform face area (FFA). Neutral faces trigger lower activation in the DP group, compared to the control group, while activation for facial expressions is the same in both groups. The second main result is that compared to controls, DPs have increased activation for bodies in the inferior occipital gyrus (IOG) and for neutral faces in the extrastriate body area (EBA), indicating that body and face sensitive processes are less categorically segregated in DP. Taken together our study shows the importance of using naturalistic emotional stimuli for a better understanding of developmental face deficits
Chloroplast two-component systems: evolution of the link between photosynthesis and gene expression
Two-component signal transduction, consisting of sensor kinases and response regulators, is the predominant signalling mechanism in bacteria. This signalling system originated in prokaryotes and has spread throughout the eukaryotic domain of life through endosymbiotic, lateral gene transfer from the bacterial ancestors and early evolutionary precursors of eukaryotic, cytoplasmic, bioenergetic organelles—chloroplasts and mitochondria. Until recently, it was thought that two-component systems inherited from an ancestral cyanobacterial symbiont are no longer present in chloroplasts. Recent research now shows that two-component systems have survived in chloroplasts as products of both chloroplast and nuclear genes. Comparative genomic analysis of photosynthetic eukaryotes shows a lineage-specific distribution of chloroplast two-component systems. The components and the systems they comprise have homologues in extant cyanobacterial lineages, indicating their ancient cyanobacterial origin. Sequence and functional characteristics of chloroplast two-component systems point to their fundamental role in linking photosynthesis with gene expression. We propose that two-component systems provide a coupling between photosynthesis and gene expression that serves to retain genes in chloroplasts, thus providing the basis of cytoplasmic, non-Mendelian inheritance of plastid-associated characters. We discuss the role of this coupling in the chronobiology of cells and in the dialogue between nuclear and cytoplasmic genetic systems
Helical distribution of the bacterial chemoreceptor via colocalization with the Sec protein translocation machinery
In Escherichia coli, chemoreceptor clustering at a cell pole seems critical for signal amplification and adaptation. However, little is known about the mechanism of localization itself. Here we examined whether the aspartate chemoreceptor (Tar) is inserted directly into the polar membrane by using its fusion to green fluorescent protein (GFP). After induction of Tar–GFP, fluorescent spots first appeared in lateral membrane regions, and later cell poles became predominantly fluorescent. Unexpectedly, Tar–GFP showed a helical arrangement in lateral regions, which was more apparent when a Tar–GFP derivative with two cysteine residues in the periplasmic domain was cross-linked to form higher oligomers. Moreover, similar distribution was observed even when the cytoplasmic domain of the double cysteine Tar–GFP mutant was replaced by that of the kinase EnvZ, which does not localize to a pole. Observation of GFP–SecE and a translocation-defective MalE–GFP mutant, as well as indirect immunofluorescence microscopy on SecG, suggested that the general protein translocation machinery (Sec) itself is arranged into a helical array, with which Tar is transiently associated. The Sec coil appeared distinct from the MreB coil, an actin-like cytoskeleton. These findings will shed new light on the mechanisms underlying spatial organization of membrane proteins in E. coli
Neutron scattering search for static magnetism in oxygen ordered YBa2Cu3O6.5
We present elastic and inelastic neutron scattering results on highly oxygen
ordered YBa2Cu3O6.5 ortho-II. We find no evidence for the presence of ordered
magnetic moments to a sensitivity of 0.003 Bohr magnetons, an order of
magnitude smaller than has been suggested in theories of orbital or
d-density-wave (DDW) currents. The absence of sharp elastic peaks, shows that
the d-density-wave phase is not present, at least for the superconductor with
the doping of 6.5 and the ordered ortho-II structure. We cannot exclude the
possibility that a broad peak may exist with extremely short-range DDW
correlations. For less ordered or more doped crystals it is possible that
disorder may lead to static magnetism. We have also searched for the large
normal state spin gap that is predicted to exist in an ordered DDW phase.
Instead of a gap we find that the Q-correlated spin susceptibility persists to
the lowest energies studied, 6 meV. Our results are compatible with the
coexistence of superconductivity with orbital currents, but only if they are
dynamic, and exclude a sharp phase transition to an ordered d-density-wave
phase.Comment: 6 pages 4 figures RevTex Submitted to Phys Rev B January 23, 200
Hadron Production in Heavy Ion Collisions
We review hadron production in heavy ion collisions with emphasis on pion and
kaon production at energies below 2 AGeV and on partonic collectivity at RHIC
energies.Comment: 31 pages, 26 figures, accepted for publication in Landolt-Boernstein
Volume 1-23
Strangeness Enhancement in and Interactions at SPS Energies
The systematics of strangeness enhancement is calculated using the HIJING and
VENUS models and compared to recent data on , and
collisions at CERN/SPS energies (). The HIJING model is used to
perform a {\em linear} extrapolation from to . VENUS is used to
estimate the effects of final state cascading and possible non-conventional
production mechanisms. This comparison shows that the large enhancement of
strangeness observed in collisions, interpreted previously as possible
evidence for quark-gluon plasma formation, has its origins in non-equilibrium
dynamics of few nucleon systems. % Strangeness enhancement %is therefore traced
back to the change in the production dynamics %from to minimum bias
and central collisions. A factor of two enhancement of at
mid-rapidity is indicated by recent data, where on the average {\em one}
projectile nucleon interacts with only {\em two} target nucleons. There appears
to be another factor of two enhancement in the light ion reaction relative
to , when on the average only two projectile nucleons interact with two
target ones.Comment: 29 pages, 8 figures in uuencoded postscript fil
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