3,670 research outputs found

    Analytic thinking reduces belief in conspiracy theories

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    Belief in conspiracy theories has been associated with a range of negative health, civic, and social outcomes, requiring reliable methods of reducing such belief. Thinking dispositions have been highlighted as one possible factor associated with belief in conspiracy theories, but actual relationships have only been infrequently studied. In Study 1, we examined associations between belief in conspiracy theories and a range of measures of thinking dispositions in a British sample (N = 990). Results indicated that a stronger belief in conspiracy theories was significantly associated with lower analytic thinking and open-mindedness and greater intuitive thinking. In Studies 2–4, we examined the causational role played by analytic thinking in relation to conspiracist ideation. In Study 2 (N = 112), we showed that a verbal fluency task that elicited analytic thinking reduced belief in conspiracy theories. In Study 3 (N = 189), we found that an alternative method of eliciting analytic thinking, which related to cognitive disfluency, was effective at reducing conspiracist ideation in a student sample. In Study 4, we replicated the results of Study 3 among a general population sample (N = 140) in relation to generic conspiracist ideation and belief in conspiracy theories about the July 7, 2005, bombings in London. Our results highlight the potential utility of supporting attempts to promote analytic thinking as a means of countering the widespread acceptance of conspiracy theories

    Girl in the cellar: a repeated cross-sectional investigation of belief in conspiracy theories about the kidnapping of Natascha Kampusch

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    The present study utilized a repeated cross-sectional survey design to examine belief in conspiracy theories about the abduction of Natascha Kampusch. At two time points (October 2009 and October 2011), participants drawn from independent cross-sections of the Austrian population (Time Point 1, N = 281; Time Point 2, N = 277) completed a novel measure of belief in conspiracy theories concerning the abduction of Kampusch, as well as measures of general conspiracist ideation, self-esteem, paranormal and superstitious beliefs, cognitive ability, and media exposure to the Kampusch case. Results indicated that although belief in the Kampusch conspiracy theory declined between testing periods, the effect size of the difference was small. In addition, belief in the Kampusch conspiracy theory was significantly predicted by general conspiracist ideation at both time points. The need to conduct further longitudinal tests of conspiracist ideation is emphasized in conclusion

    Single-injection thoracic paravertebral block for postoperative pain treatment after thoracoscopic surgery

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    Background. Thoracoscopic surgery can be associated with considerable postoperative pain. While the benefits of paravertebral block on pain after thoracotomy have been demonstrated, no investigations on the effects of paravertebral block on pain after thoracoscopy have been conducted. We tested the hypothesis that a single-injection thoracic paravertebral block, performed preoperatively, reduces pain scores after thoracoscopic surgery. Methods. Of 45 patients recruited, 40 completed the study. They were randomly allocated to two groups: the paravertebral group received i.v. patient-controlled analgesia (PCA) with morphine plus single-injection thoracic paravertebral block with bupivacaine 0.375% and adrenaline 1:200 000 0.4 ml kg−1 (n=20). The control group was treated with a back puncture without injection and morphine PCA (n=20). Results. The main outcomes recorded during 48 h after surgery were pain scores using the visual analogue scale (VAS, 0-100). Secondary outcomes were cumulative morphine consumption and peak expiratory flow rate (PEFR). Half an hour and 24 h after surgery, median (25th-75th percentiles) VAS on coughing in the paravertebral group was 31.0 (20.0-55.0) and 30.5 (17.5-40.0) respectively and in the control group it was 70.0 (30.0-100.0) and 50.0 (25.0-75.0) respectively. The difference between the groups over the whole observation period was statistically significant (P<0.05). Twenty-four and 48 h after surgery, median (25th-75th percentiles) cumulative morphine consumption (mg) was 49.0 (38.3-87.0) and 69.3 (38.8-118.5) respectively in the paravertebral group and 51.2 (36.0-84.1) and 78.1 (38.4-93.1) in the control group (statistically not significant). No differences were found in PEFR or the incidence of any side-effects between groups. Conclusion. We conclude that single-shot preoperative paravertebral block improves post-operative pain treatment after thoracoscopic surgery in a clinically significant fashio

    Extrakorporale Stoßwellentherapie eines komplizierten chronischen Ulcus cruris venosum

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    Zusammenfassung: Extrakorporale Stoßwellen werden definiert als eine Sequenz von akustischen Schallimpulsen, die einen charakteristisch schnellen Druckanstieg auf ĂŒber 100MPa mit Abfall auf Normaldruck in wenigen Mikrosekunden aufweisen. In den 1980er-Jahren wurde die extrakorporale Stoßwellenlithotripsie (ESWL) erstmals zur Behandlung der Urolithiasis angewandt. OrthopĂ€den setzten anschließend die extrakorporale Stoßwellentherapie (ESWT) zur Behandlung von nicht heilenden Frakturen, Tendinopathien und Osteonekrose ein. Die erste Anwendung von ESWT in der Dermatologie erfolgte zur Behandlung des chronischen Ulcus cruris. Verschiedene Studien der letzten 10Jahre zeigten, dass die ESWT die Angiogenese stimuliert und die Perfusion im ischĂ€mischen Gewebe verbessert, die EntzĂŒndungsreaktion mindert, die Zelldifferenzierung unterstĂŒtzt und hiermit die Wundheilung deutlich verbessern kann. Wir setzten die ESWT erfolgreich zur Behandlung eines komplizierten chronischen venösen Ulcus cruris ein. Weiter konnten wir eine Verbesserung des lymphatischen Abflusses nach Applikation von ESWT beobachten. Die ESWT stellt somit eine nebenwirkungsarme und effiziente physikalische TherapiemodalitĂ€t zur Behandlung von therapieresistenten chronischen Wunden da

    What Drives Our Emotions When We Watch Sporting Events? An ESM Study on the Affective Experience of German Spectators during the 2018 FIFA World Cup

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    There is ample evidence that watching sports induces strong emotions that translate into manifold consequential behaviours. However, it is rather ill-understood how exactly spectators’ emotions unfold during soccer matches and what determines their intensity. To address these questions, we used the 2018 FIFA World Cup as a natural quasi-experiment to conduct a pre-registered study on spectators’ emotional experiences. Employing an app-based experience-sampling design, we tracked 251 German spectators during the tournament and assessed high-resolution changes in core affect (valence, activation) throughout soccer matches. Across the three German matches, multi-level models revealed that all spectators exhibited strong changes on both affective dimensions in response to Germany’s performance. Although fans experienced slightly more intense affect than non-fans, particularly during losses, this moderating effect was very small in comparison to the magnitude of the affective fluctuations that occurred independent of fan identity. Taken together, the findings suggest group emotions (collectively felt emotion irrespective of individual affiliation) rather than group-affiliation based emotions (individually felt emotion because of an affiliated group), as the dominant process underlying spectator affect during the 2018 FIFA World Cup.</jats:p

    Navigation und Robotik an der Otobasis

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    Zusammenfassung: Die bildgestĂŒtzten computerassistierten mikroskopischen Eingriffe an der Otobasis stellen einen seltenen Eingriff in der tĂ€glichen Praxis dar. Es handelt sich jedoch um delikate und schwierige minimalinvasive Eingriffe, da die Orientierung im Felsenbein bis zur Felsenbeinspitze oft schwierig ist. Bei Malformationen oder Tumoren sind die normalen anatomischen Landmarken, die dem Chirurgen als Orientierung dienen, hĂ€ufig nicht vorhanden. Die Navigation, zusammen mit den bildgebenden Verfahren wie CT, MRT und Angiographie, hilft dem Chirurgen, sich bei unĂŒbersichtlichen VerhĂ€ltnissen im Raum zu orientieren, um die Operation auf diese Weise sicherer und z.T. auch schneller durchzufĂŒhren. Weltweite einheitliche Indikationen zum Einsatz an der Otobasis fehlen aber. Die navigationsgestĂŒtzte Miniaturrobotik ist noch in den ersten praktischen Testphase

    Computer-Assisted Precision Surgery in the Ear

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    Chirurgische Eingriffe am Ohr stellen aufgrund der komplexen Anatomie und der GrössenverhĂ€ltnisse der beteiligten anatomischen Strukturen eine Herausforderung fĂŒr den HNO-Chirurgen dar. In diesem Beitrag wird ein Ansatz fĂŒr die roboterbasierte Navigation zur HörgerĂ€teimplantation vorgestellt. Insbesondere wird auf die Möglichkeit des FrĂ€sens von Implantatlagern im Felsenbein eingegangen. Je prĂ€ziser ein Implantat im SchĂ€del verankert werden kann, desto einfacher ist der chirurgischen Ablauf. Weiterhin, profitieren Patienten von verkĂŒrzten Operationszeiten und weniger schmerzhaften Eingriffen.Traditional surgical procedures involving the implantation of artificial hearing devices in the inner ear are challenging due to the size and complexity of anatomical structures within the temporal bone. To date, no stereotactic instrument guidance technology providing the necessary levels of accuracy is available. This work presents an approach to robot assisted implantation of hearing devices. Specifically, the robot system was used to milla cavity to for a direct acoustical stimulation implant. As the precision of such cavities increases, so also can future implant generations improve in terms of size, complexity and cost effectiveness. Additionally, patients themselves would profit from shorter procedure times and less painful interventions

    Pharmacological manipulation of L-carnitine transport into L6 cells with stable overexpression of human OCTN2

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    Abstract.: The high-affinity Na+-dependent carnitine transporter OCTN2 (SLC22A5) has a high renal expression and reabsorbs most filtered carnitine. To gain more insight into substrate specificity of OCTN2, we overexpressed hOCTN2 in L6 cells and characterized the structural requirements of substances acting as human OCTN2 (hOCTN2) inhibitors. A 1905-bp fragment containing the hOCTN2 complete coding sequence was introduced into the pWpiresGFP vector, and L6 cells were stably transduced using a lentiviral system. The transduced L6 cells revealed increased expression of hOCTN2 on the mRNA, protein and functional levels. Structural requirements for hOCTN2 inhibition were predicted in silico and investigated in vitro. Essential structural requirements for OCTN2 inhibition include a constantly positively charged nitrogen atom and a carboxyl, nitrile or ester group connected by a 2-4-atom linker. Our cell system is suitable for studying in vitro interactions with OCTN2, which can subsequently be investigated in viv

    Functional identification of Arabidopsis ATSIP2 (At3g57520) as an alkaline α-galactosidase with a substrate specificity for raffinose and an apparent sink-specific expression patter

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    Arabidopsis ATSIP2 has recently been suggested to be a raffinose synthase gene. However, it has high amino acid identity to functionally characterized alkaline α-galactosidases from Cucumis melo and Zea mays. Using the Sf9 insect cell expression system, we demonstrate that recombinant ATSIP2 is a genuine alkaline α-galactosidase with a distinct substrate specificity for raffinose, and not a raffinose synthase. A ÎČ-glucuronidase reporter construct using the ATSIP2 promoter shows that ATSIP2 is strongly expressed in sink tissues of Arabidopsis, i.e. sink leaves and non-xylem parts of the root stele, suggesting a physiological function in raffinose phloem unloading
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