Glasgow's spatial arrangement of deprivation over time: methods to measure it and meanings for health

Background: Socio-economic deprivation is a key driver of population health. High levels of socio-economic deprivation have long been offered as the explanation for exceptionally high levels of mortality in Glasgow, Scotland. A number of recent studies have, however, suggested that this explanation is partial. Comparisons with Liverpool and Manchester suggest that mortality rates have been higher in Glasgow since the 1970s despite very similar levels of deprivation in these three cities. It has, therefore, been argued that there is an “excess” of mortality in Glasgow; that is, mortality rates are higher than would be expected given the city’s age, gender, and deprivation profile. A profusion of possible explanations for this excess has been proffered. One hypothesis is that the spatial arrangement of deprivation might be a contributing factor. Particular spatial configurations of deprivation have been associated with negative health impacts. It has been suggested that Glasgow experienced a distinct, and more harmful, development of spatial patterning of deprivation. Measuring the development of spatial arrangements of deprivation over time is technically challenging however. Therefore, this study brought together a number of techniques to compare the development of the spatial arrangement of deprivation in Glasgow, Liverpool and Manchester between 1971 and 2011. It then considered the plausibility of the spatial arrangement of deprivation as a contributing factor to Glasgow’s high levels of mortality. Methods: A literature review was undertaken to inform understandings of relationships between the spatial arrangement of deprivation and health outcomes. A substantial element of this study involved developing a methodology to facilitate temporal and inter-city comparisons of the spatial arrangement of deprivation. Key contributions of this study were the application of techniques to render and quantify whole-landscape perspectives on the development of spatial patterns of household deprivation, over time. This was achieved by using surface mapping techniques to map information relating to deprivation from the UK census, and then analysing these maps with spatial metrics. Results: There is agreement in the literature that the spatial arrangement of deprivation can influence health outcomes, but mechanisms and expected impacts are not clear. The temporal development of Glasgow’s spatial arrangement of deprivation exhibited both similarities and differences with Liverpool and Manchester. Glasgow often had a larger proportion of its landscape occupied with areas of deprivation, particularly in 1971 and 1981. Patch density and mean patch size (spatial metrics which provide an indication of fragmentation), however, were not found to have developed differently in Glasgow. Conclusion: The spatial extent of deprivation developed differently in Glasgow relative to Liverpool and Manchester as the results indicated that deprivation was substantially more spatially prevalent in Glasgow, this was particularly pronounced in 1971 and 1981. This implies that exposure of more affluent and deprived people to each other has been greater in Glasgow. Given that proximal inequality has been related to poor health outcomes, it would appear plausible that this may have adversely affected Glasgow’s mortality rates. If this is the case, however, it is unlikely that this will account for a substantial proportion of Glasgow’s excess mortality. Further research into Glasgow’s excess mortality is, therefore, required

Can providing safe cycling infrastructure encourage people to cycle more when it rains? The use of crowdsourced cycling data (Strava)

Many local authorities in the UK and other developed countries have spent a substantial amount of time and money providing safe cycling infrastructure to improve cycling environments. However, it is not clear whether these expensive physical investments are an effective strategy to encourage people to cycle more in cities where there is a high level of precipitation. The evidence is limited, partly due to data limitations. We used crowdsourced cycling data (taken from the Strava activity-tracking app) and fixed-effects panel regression models to investigate whether providing safe cycling infrastructure could be an effective way to overcome adverse weather conditions. We selected the city centre of Glasgow, Scotland because of the current size and scope of investments. We found that providing safe cycle paths could encourage people to cycle more, especially on dry days. However, findings suggested that rainy cities like Glasgow may not have realised the full benefits of safe cycling infrastructure because there are larger reductions in the volume of cycling on rainy days on these routes. Planners, especially from cities with a high level of precipitation, should consider how to improve cycle paths to overcome adverse weather and other policies (e.g., providing shower facilities at workplaces, incentives to cycle, etc.) to increase cyclists’ resilience to bad weather

Using population surfaces and spatial metrics to track the development of deprivation landscapes in Glasgow, Liverpool, and Manchester between 1971 and 2011

Measuring change in the spatial arrangement of deprivation over time, and making international, inter-city comparisons, is technically challenging. Meeting these challenges offers a means of furthering understanding and providing new insights into the geography of urban poverty and deprivation. In this paper, we introduce a novel approach to mapping and analysing spatio-temporal patterns of household deprivation, assessing the distribution at the landscape level. The approach we develop has advantages over existing techniques because it is applicable in situations where i) conventional approaches based on choropleth mapping are not feasible due to boundary change and/or ii) where spatial relationships at a landscape level are of interest. Through the application of surface mapping techniques to disaggregate census count data, and by applying spatial metrics commonly used in ecology, we were able to compare the development of the spatial arrangement of deprivation between 1971 and 2011 in three UK cities of particular interest: Glasgow, Manchester and Liverpool. Applying three spatial metrics – spatial extent, patch density, and mean patch size – revealed that over the 40 year period household deprivation has been more spatially dispersed in Glasgow. This novel approach has enabled an analysis of deprivation distributions over time which is less affected by boundary change and which accurately assesses and quantifies the spatial relationships between those living with differing levels of deprivation. It thereby offers a new approach for researchers working in this area

Feasibility trial evaluation of a physical activity and screen-viewing course for parents of 6 to 8 year-old children : Teamplay

Background: Many children spend too much time screen-viewing (watching TV, surfing the internet and playing video games) and do not meet physical activity (PA) guidelines. Parents are important influences on children’s PA and screen-viewing (SV). There is a shortage of parent-focused interventions to change children’s PA and SV. Methods: Teamplay was a two arm individualized randomized controlled feasibility trial. Participants were parents of 6–8 year old children. Intervention participants were invited to attend an eight week parenting program with each session lasting 2 hours. Children and parents wore an accelerometer for seven days and minutes of moderate-to-vigorous intensity PA (MVPA) were derived. Parents were also asked to report the average number of hours per day that both they and the target child spent watching TV. Measures were assessed at baseline (time 0) at the end of the intervention (week 8) and 2 months after the intervention had ended (week 16). Results: There were 75 participants who provided consent and were randomized but 27 participants withdrew post-randomization. Children in the intervention group engaged in 2.6 fewer minutes of weekday MVPA at Time 1 but engaged in 11 more minutes of weekend MVPA. At Time 1 the intervention parents engaged in 9 more minutes of weekday MVPA and 13 more minutes of weekend MVPA. The proportion of children in the intervention group watching ≥ 2 hours per day of TV on weekend days decreased after the intervention (time 0 = 76%, time 1 = 39%, time 2 = 50%), while the control group proportion increased slightly (79%, 86% and 87%). Parental weekday TV watching decreased in both groups. In post-study interviews many mothers reported problems associated with wearing the accelerometers. In terms of a future full-scale trial, a sample of between 80 and 340 families would be needed to detect a mean difference of 10-minutes of weekend MVPA. Conclusions: Teamplay is a promising parenting program in an under-researched area. The intervention was acceptable to parents, and all elements of the study protocol were successfully completed. Simple changes to the trial protocol could result in more complete data collection and study engagement

Parental modelling, media equipment and screen-viewing among young children : cross-sectional study

Objective: To examine whether parental screenviewing, parental attitudes or access to media equipment were associated with the screen-viewing of 6-year-old to 8-year-old children. Design: Cross-sectional survey. Setting: Online survey. Main outcome: Parental report of the number of hours per weekday that they and, separately, their 6- year-old to 8-year-old child spent watching TV, using a games console, a smart-phone and multiscreen viewing. Parental screen-viewing, parental attitudes and pieces of media equipment were exposures. Results: Over 75% of the parents and 62% of the children spent more than 2 h/weekday watching TV. Over two-thirds of the parents and almost 40% of the children spent more than an hour per day multiscreen viewing. The mean number of pieces of media equipment in the home was 5.9 items, with 1.3 items in the child’s bedroom. Children who had parents who spent more than 2 h/day watching TV were over 7.8 times more likely to exceed the 2 h threshold. Girls and boys who had a parent who spent an hour or more multiscreen viewing were 34 times more likely to also spend more than an hour per day multiscreen viewing. Media equipment in the child’s bedroom was associated with higher TV viewing, computer time and multiscreen viewing. Each increment in the parental agreement that watching TV was relaxing for their child was associated with a 49% increase in the likelihood that the child spent more than 2 h/day watching TV. Conclusions: Children who have parents who engage in high levels of screen-viewing are more likely to engage in high levels of screen-viewing. Access to media equipment, particularly in the child’s bedroom, was associated with higher levels of screen-viewing. Family-based strategies to reduce screen-viewing and limit media equipment access may be important ways to reduce child screen-viewing

Process evaluation of the Teamplay parenting intervention pilot : implications for recruitment, retention and course refinement

Background Parenting programs could provide effective routes to increasing children’s physical activity and reducing screen-viewing. Many studies have reported difficulties in recruiting and retaining families in group parenting interventions. This paper uses qualitative data from the Teamplay feasibility trial to examine parents’ views on recruitment, attendance and course refinement. Methods Semi-structured interviews were conducted with 16 intervention and 10 control group parents of 6–8 year old children. Topics discussed with the intervention group included parents’ views on the recruitment, structure, content and delivery of the course. Topics discussed with the control group included recruitment and randomization. Interviews were digitally recorded, transcribed and thematically analyzed. Results Many parents in both the intervention and control group reported that they joined the study because they had been thinking about ways to improve their parenting skills, getting ideas on how to change behavior, or had been actively looking for a parenting course but with little success in enrolling on one. Both intervention and control group parents reported that the initial promotional materials and indicative course topics resonated with their experiences and represented a possible solution to parenting challenges. Participants reported that the course leaders played an important role in helping them to feel comfortable during the first session, engaging anxious parents and putting parents at ease. The most commonly reported reason for parents returning to the course after an absence was because they wanted to learn new information. The majority of parents reported that they formed good relationships with the other parents in the group. An empathetic interaction style in which leaders accommodated parent’s busy lives appeared to impact positively on course attendance. Conclusions The data presented indicate that a face-to-face recruitment campaign which built trust and emphasized how the program was relevant to families positively affected recruitment in Teamplay. Parents found the parenting component of the intervention attractive and, once recruited, attendance was facilitated by enjoyable sessions, empathetic leaders and support from fellow participants. Overall, data suggest that the Teamplay recruitment and retention approaches were successful and with small refinements could be effectively used in a larger trial

Evaluation of the effectiveness and cost-effectiveness of Families for Health V2 for the treatment of childhood obesity : study protocol for a randomized controlled trial

Background: Effective programs to help children manage their weight are required. Families for Health focuses on a parenting approach, designed to help parents develop their parenting skills to support lifestyle change within the family. Families for Health V1 showed sustained reductions in overweight after 2 years in a pilot evaluation, but lacks a randomized controlled trial (RCT) evidence base. Methods/design: This is a multi-center, investigator-blind RCT, with parallel economic evaluation, with a 12-month follow-up. The trial will recruit 120 families with at least one child aged 6 to 11 years who is overweight (≥91st centile BMI) or obese (≥98th centile BMI) from three localities and assigned randomly to Families for Health V2 (60 families) or the usual care control (60 families) groups. Randomization will be stratified by locality (Coventry, Warwickshire, Wolverhampton). Families for Health V2 is a family-based intervention run in a community venue. Parents/carers and children attend parallel groups for 2.5 hours weekly for 10 weeks. The usual care arm will be the usual support provided within each NHS locality. A mixed-methods evaluation will be carried out. Child and parent participants will be assessed at home visits at baseline, 3-month (post-treatment) and 12-month follow-up. The primary outcome measure is the change in the children’s BMI z-scores at 12 months from the baseline. Secondary outcome measures include changes in the children’s waist circumference, percentage body fat, physical activity, fruit/vegetable consumption and quality of life. The parents’ BMI and mental well-being, family eating/activity, parent–child relationships and parenting style will also be assessed. Economic components will encompass the measurement and valuation of service utilization, including the costs of running Families for Health and usual care, and the EuroQol EQ-5D health outcomes. Cost-effectiveness will be expressed in terms of incremental cost per quality-adjusted life year gained. A de novo decision-analytic model will estimate the lifetime cost-effectiveness of the Families for Health program. Process evaluation will document recruitment, attendance and drop-out rates, and the fidelity of Families for Health delivery. Interviews with up to 24 parents and children from each arm will investigate perceptions and changes made. Discussion: This paper describes our protocol to assess the effectiveness and cost-effectiveness of a parenting approach for managing childhood obesity and presents challenges to implementation. Trial registration: Current Controlled Trials ISRCTN4503220

Sex Differences in Cerebral Small Vessel Disease: A Systematic Review and Meta-Analysis

Background: Cerebral small vessel disease (SVD) is a common cause of stroke, mild cognitive impairment, dementia and physical impairments. Differences in SVD incidence or severity between males and females are unknown. We assessed sex differences in SVD by assessing the male-to-female ratio (M:F) of recruited participants and incidence of SVD, risk factor presence, distribution, and severity of SVD features. Methods: We assessed four recent systematic reviews on SVD and performed a supplementary search of MEDLINE to identify studies reporting M:F ratio in covert, stroke, or cognitive SVD presentations (registered protocol: CRD42020193995). We meta-analyzed differences in sex ratios across time, countries, SVD severity and presentations, age and risk factors for SVD. Results: Amongst 123 relevant studies (n = 36,910 participants) including 53 community-based, 67 hospital-based and three mixed studies published between 1989 and 2020, more males were recruited in hospital-based than in community-based studies [M:F = 1.16 (0.70) vs. M:F = 0.79 (0.35), respectively; p < 0.001]. More males had moderate to severe SVD [M:F = 1.08 (0.81) vs. M:F = 0.82 (0.47) in healthy to mild SVD; p < 0.001], and stroke presentations where M:F was 1.67 (0.53). M:F did not differ for recent (2015–2020) vs. pre-2015 publications, by geographical region, or age. There were insufficient sex-stratified data to explore M:F and risk factors for SVD. Conclusions: Our results highlight differences in male-to-female ratios in SVD severity and amongst those presenting with stroke that have important clinical and translational implications. Future SVD research should report participant demographics, risk factors and outcomes separately for males and females. Systematic Review Registration: [PROSPERO], identifier [CRD42020193995]

A qualitative study of primary care clinicians' views of treating childhood obesity

Background: The prevalence of childhood obesity is rising and the UK Government have stated a commitment to addressing obesity in general. One method has been to include indicators relating to obesity within the GP pay-for-performance Quality and Outcomes Framework (QOF) contract. This study aimed to explore general practitioners' and practice nurses' views in relation to their role in treating childhood obesity. Methods: We interviewed eighteen practitioners (twelve GPs and six nurses) who worked in general practices contracting with Rotherham Primary Care Trust. Interviews were face to face and semi structured. The transcribed data were analysed using framework analysis. Results: GPs and practice nurses felt that their role was to raise the issue of a child's weight, but that ultimately obesity was a social and family problem. Time constraint, lack of training and lack of resources were identified as important barriers to addressing childhood obesity. There was concern that the clinician-patient relationship could be adversely affected by discussing what was often seen as a sensitive topic. GPs and practice nurses felt ill-equipped to tackle childhood obesity given the lack of evidence for effective interventions, and were sceptical that providing diet and exercise advice would have any impact upon a child's weight. Conclusion: GPs and practice nurses felt that their role in obesity management was centred upon raising the issue of a child's weight, and providing basic diet and exercise advice. Clinicians may find it difficult to make a significant impact on childhood obesity while the evidence base for effective management remains poor. Until the lack of effective interventions is addressed, implementing additional targets (for example through the QOF) may not be effective