A sociotechnical history of the ultralightweight wheelchair: a vehicle of social change

The emergence of the ultralightweight wheelchair has transformed the lives of millions of disa-bled people. It has radically changed the principles and practices of wheelchair design, manufac-ture and prescription and redefined wheelchair users and wheelchair use. Designed and built largely by wheelchair users themselves it was driven initially by a desire to improve sport perfor-mance and later by a wish for improved access to the community and built environment. In this paper we draw on oral histories and documentary sources to reconstruct its socio-technical histo-ry. We employ the analytical concept of ‘boundary object’ to illuminate how the wheelchair as a technological artefact is implicated in relations of social change and show the role of wheelchair users in the development and emergence of the ultra-lightweight wheelchair. We highlight the tensions and negotiations within this history and the push and pull between different social groups. The emergence of the ultra-lightweight wheelchair helped to reconfigure ideas about wheelchairs and their users and allowed wheelchairs to gain a foothold within broader social and technological infrastructures. What makes this account powerful is that this is a success story for a group who have historically been excluded from design processes

Towards a Bourdieusian analysis of the disabled body and practice: embodying negative symbolic capitals and the uneasy experience of hysteresis

Within the last few years, disabled people have become the target of government austerity measures through drastic cuts to welfare justified through the portrayal of benefit claimants as inactive, problem citizens who are wilfully unemployed. For all that is wrong with these cuts, they are one of many aspects of exclusion that disabled people face. Attitudes towards disability are deteriorating (Scope, 2011) and disabled people are devalued and negatively positioned in a myriad of ways, meaning that an understanding of the perceptions and positioning of disability and the power of disabling practices is critical. This thesis will examine how Bourdieu’s theoretical repertoire may be applied to the area of Disability Studies in order to discern how society produces oppressive and exclusionary systems of classification which structures the social position and perceptions of disability. The composite nature of disability and multiple forms of exclusion and inequality associated with it benefits from a multipronged approach which acknowledges personal, embodied and psychological aspects of disability alongside socio-political and cultural conceptualisations. Bourdieu’s approach is one in which the micro and macro aspects of social life are brought together through their meso interplay and provides a thorough analysis of the many aspects of disability

Meadows and more: a botanical journal of five days on the Uists, Benbecula and Eriskay

In the first week of July 2018, the Floodplain Meadows Partnership (FMP) held its annual steering group meeting with field excursions on the Outer Hebrides. The aim of the field part of our meeting was to familiarise ourselves with wet meadows (including those on machair) of the Uists and Benbecula, and compare their composition and ecology with related habitats further south in the UK. However, a chance for us to explore the other habitats of these islands was too good an opportunity to miss. Hence five of us arrived on the islands a few days before the main group and roamed more extensively, looking at a wide range of habitats in addition to meadows. The lead author’s role in this botanical journal was to note incidental observations made in addition to the formal study of the meadows. Hilary Wallace directed the quadrat recording in wet meadows, and the overall programme of work was coordinated by David Gowing and Emma Rothero of the Open University. Even during the FMP field excursions, we could not ignore other habitats entirely and Stewart Clarke (National Trust Freshwaters and Estuaries Specialist) paid special attention to the aquatic flora

Meadows and more: a botanical journal of five days on the Uists, Benbecula and Eriskay

In the first week of July 2018, the Floodplain Meadows Partnership (FMP) held its annual steering group meeting with field excursions on the Outer Hebrides. The aim of the field part of our meeting was to familiarise ourselves with wet meadows (including those on machair) of the Uists and Benbecula, and compare their composition and ecology with related habitats further south in the UK. However, a chance for us to explore the other habitats of these islands was too good an opportunity to miss. Hence five of us arrived on the islands a few days before the main group and roamed more extensively, looking at a wide range of habitats in addition to meadows. The lead author’s role in this botanical journal was to note incidental observations made in addition to the formal study of the meadows. Hilary Wallace directed the quadrat recording in wet meadows, and the overall programme of work was coordinated by David Gowing and Emma Rothero of the Open University. Even during the FMP field excursions, we could not ignore other habitats entirely and Stewart Clarke (National Trust Freshwaters and Estuaries Specialist) paid special attention to the aquatic flora

Preparing for the Genomic Age: Thiopurine S-Methytransferase Polymorphism

Interpatient variability among medication doses has been a long-standing obstacle for many prescribers. Some medications result in increased morbidity and mortality in a small percentage of the population. For many years, the cause of such toxicities was unknown. This mystery has been resolved by the discovery that the abscence or abnormality of specific genes that code for receptros, drug-treated proteins, drug transport mechanisms, and drug metabolizing enzymes could alter how an affected individual will respond to a given drug. One such incidence is the genetic polymorphism in thiopurine s-methytransferase (TPMT). In comprehending the mechanism of this polymorphism, it is important to understand the matabolic pathway of thiopurine drugs. Through study of this pathway, researchers began to look into whether other polymorphisms aside from TPMT could be a source of the dose-related toxicity with the thiopurines. The prospect that this polymorphism may contribute to an increase in number or exacerbation of side effects beyond the commonly presented bone marrow toxicity also has been visited. Becoming more aware of this genetic issue has presented the need to evaluate the cost effectiveness of genetic testing to counteract the expected cost of treating extreme myelosuppression. Having knowledge of new pharmacogenomic technology and the tests available can benefit pharmacists in any setting. Pharmacists will be more prepared to address patient concerns such as necessity and cost effectiveness

Digital Support for Living with and Beyond Gynaecological Cancer

Introduction Gynae-Radiotherapy places exceptional psychosocial and physical burdens on patients. Technological developments and associated acute toxicity and survival outcomes have improved, however holistic support has not kept pace. Digital technologies have potential to enhance support and patient experience. The project aimed to co-create a prototype of a digital health intervention that could serve the needs of women living with and beyond treatment for gynaecological cancer. Methods A multi-disciplinary and co-creation approach was adopted. Four workshops were held, comprising of a number of activities to support participants’ expression of views and facilitate discussion. Methods included word cloud generation, prompt cards, empathy maps and persona creation, domain storylines and requirements identification. Results Support drops off dramatically once treatment is completed. Patients struggled to adjust to their ‘new normal’ and felt unprepared for changes post-treatment. Patients felt overwhelmed with leaflets yet wanted instant access to reliable and relevant information in one place, better information on late side effects and improved communication about sexual health and sexuality. Reassurance through a digital intervention was viewed positively and specific ideas for achieving this were suggested through: Sharing experiences; targeted practical advice; peer support and advice/support for significant others. Conclusion The co-creation of a prototype generated further discussion and an interactive prototype was developed. Based on workshop findings it is believed that the intervention could provide life-long support for women living with and beyond cancer. Implications for practice Increased focus is needed on the late effects of radiotherapy, specifically in supporting psychosocial wellbeing. Co-creation is a rewarding and fulfilling activity that met numerous aims beyond those of the project. It is recommended that mixed staff-patient groups are developed and adopted in more informal ways for the improvement of services

Hydrogen limitation and syntrophic growth among natural assemblages of thermophilic methanogens at deep-sea hydrothermal vents

© The Author(s), 2016. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Frontiers in Microbiology 7 (2016): 1240, doi:10.3389/fmicb.2016.01240.Thermophilic methanogens are common autotrophs at hydrothermal vents, but their growth constraints and dependence on H2 syntrophy in situ are poorly understood. Between 2012 and 2015, methanogens and H2-producing heterotrophs were detected by growth at 80∘C and 55∘C at most diffuse (7–40∘C) hydrothermal vent sites at Axial Seamount. Microcosm incubations of diffuse hydrothermal fluids at 80∘C and 55∘C demonstrated that growth of thermophilic and hyperthermophilic methanogens is primarily limited by H2 availability. Amendment of microcosms with NH4+ generally had no effect on CH4 production. However, annual variations in abundance and CH4 production were observed in relation to the eruption cycle of the seamount. Microcosm incubations of hydrothermal fluids at 80∘C and 55∘C supplemented with tryptone and no added H2 showed CH4 production indicating the capacity in situ for methanogenic H2 syntrophy. 16S rRNA genes were found in 80∘C microcosms from H2-producing archaea and H2-consuming methanogens, but not for any bacteria. In 55∘C microcosms, sequences were found from H2-producing bacteria and H2-consuming methanogens and sulfate-reducing bacteria. A co-culture of representative organisms showed that Thermococcus paralvinellae supported the syntrophic growth of Methanocaldococcus bathoardescens at 82∘C and Methanothermococcus sp. strain BW11 at 60∘C. The results demonstrate that modeling of subseafloor methanogenesis should focus primarily on H2 availability and temperature, and that thermophilic H2 syntrophy can support methanogenesis within natural microbial assemblages and may be an important energy source for thermophilic autotrophs in marine geothermal environments.This work was funded by the Gordon and Betty Moore Foundation grant GBMF 3297, the NASA Earth and Space Science Fellowship Program grant NNX11AP78H, the National Science Foundation grant OCE-1547004, with funding from NOAA/PMEL, contribution #4493, and JISAO under NOAA Cooperative Agreement NA15OAR4320063, contribution #2706

Developing and establishing the psychometric properties of the Strathclyde Citizenship Measure : a new measure for health and social care practice and research

There has been increasing interest and research attention towards citizenship-based practices and care within health and social care settings. A framework for implementing citizenship-based interventions has helped support the participation in society of persons who have experienced major life disruptions. Yet, having ways to measure the impact of citizenship 'in action' within specific socio-cultural contexts has proved challenging. We report on the development of the Strathclyde Citizenship Measure (SCM) which seeks to establish a psychometrically sound measure of citizenship that is relevant to the Scottish context. We outline the three phases of developing the SCM: (1) item generation, (2) item reduction and piloting, and (3) measure validation. Having generated items for the SCM using concept mapping techniques, we piloted it with 407 participants who completed an online survey of a 60-item version of the SCM. The aims were to assess the validity of the items and reduce the number of items using principal components analysis for the final measure. This resulted in a 39 item SCM. We then sought to establish the psychometric properties of this shorter version of the SCM through testing its reliability, convergent, concurrent and discriminant validity. The 39 item SCM was administered online to 280 Scottish residents along with additional measures including the Warwick-Edinburgh Mental Well-being Scale (WEMWBS), the Depression, Anxiety and Stress Scale (DASS21), the Sense of Belonging Instrument (SOBI-A); the Big Five Personality Inventory (Shortened Version; BFI-10) and the Personal Social Capital Scale (PSCS-16). The factor structure and dimensionality of the SCM was examined using exploratory factor analysis and it was found to be reliable and valid. This paper explores the potential for the application of the SCM across health and social care settings and identifies future work to develop citizenship tools to facilitate dialogues about citizenship across health and social care practice settings