Generalized dynamic reduction in finite element dynamic optimization

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76662/1/AIAA-8826-211.pd

CCD BV and 2MASS photometric study of the open cluster NGC 1513

We present CCD BV and JHK$_{s}$ 2MASS photometric data for the open cluster NGC 1513. We observed 609 stars in the direction of the cluster up to a limiting magnitude of $V\sim19$ mag. The star count method shows that the centre of the cluster lies at $\alpha_{2000}=04^{h}09^{m}36^{s}$, $\delta_{2000}=49^{\circ}28^{'}43^{''}$ and its angular size is $r=10$ arcmin. The optical and near-infrared two-colour diagrams reveal the colour excesses in the direction of the cluster as $E(B-V)=0.68\pm0.06$, $E(J-H)=0.21\pm0.02$ and $E(J-K_{s})=0.33\pm0.04$ mag. These results are consistent with normal interstellar extinction values. Optical and near-infrared Zero Age Main-Sequences (ZAMS) provided an average distance modulus of $(m-M)_{0}=10.80\pm0.13$ mag, which can be translated into a distance of $1440\pm80$ pc. Finally, using Padova isochrones we determined the metallicity and age of the cluster as $Z=0.015\pm 0.004$ ($[M/H]=-0.10 \pm 0.10$ dex) and $\log (t/yr) = 8.40\pm0.04$, respectively.Comment: 15 pages, 12 figures and 4 tables, accepted for publication in Astrophysics & Space Scienc

A dog model using an implanted system for protracted hepatic arterial chemotherapy

A model for hepatic arterial chemotherapy studies using large dogs and an implantable infusion pump has been developed. Using this technique near complete perfusion (>90%) of the liver can be achieved in vivo as determined by hepatic arterial perfusion scintigraphy with technitium 99m macroaggregated albumin. The system is reliable and has been in use for a total of 1353 days (mean of 104 days, range 52-239) in 13 dogs. Pump implantation causes no apparent acute liver damage based on pre- and post-operative alkaline phosphatase and serum glutamic-pyruvic transaminase determinations and does not affect the general mobility or behavior of the animals. Careful placement of the catheter and attention to the physicochemical properties of the solutions loaded are factors contributing to the success of the model. The model permits comprehensive preclinical pharmacokinetic and toxicologic studies of new or preexistent chemotherapeutic agents in the same device that will be used for later administration in human subjects. By providing the means to examine and develop new treatment modalities, it enables the design of even more potent cytotoxic therapy directed into the tumor vascular bed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/25999/1/0000065.pd

Horizontal Branch Stars: The Interplay between Observations and Theory, and Insights into the Formation of the Galaxy

We review HB stars in a broad astrophysical context, including both variable and non-variable stars. A reassessment of the Oosterhoff dichotomy is presented, which provides unprecedented detail regarding its origin and systematics. We show that the Oosterhoff dichotomy and the distribution of globular clusters (GCs) in the HB morphology-metallicity plane both exclude, with high statistical significance, the possibility that the Galactic halo may have formed from the accretion of dwarf galaxies resembling present-day Milky Way satellites such as Fornax, Sagittarius, and the LMC. A rediscussion of the second-parameter problem is presented. A technique is proposed to estimate the HB types of extragalactic GCs on the basis of integrated far-UV photometry. The relationship between the absolute V magnitude of the HB at the RR Lyrae level and metallicity, as obtained on the basis of trigonometric parallax measurements for the star RR Lyrae, is also revisited, giving a distance modulus to the LMC of (m-M)_0 = 18.44+/-0.11. RR Lyrae period change rates are studied. Finally, the conductive opacities used in evolutionary calculations of low-mass stars are investigated. [ABRIDGED]Comment: 56 pages, 22 figures. Invited review, to appear in Astrophysics and Space Scienc