47 research outputs found

    UCSC Genome Browser view of CNV on chromosome 3p22.2.

    No full text
    <p>Figure produced by custom tracks listing CNV call of Negrito and uploaded to <a href="http://genome.ucsc.edu" target="_blank">http://genome.ucsc.edu</a>.</p

    CNVR map of Negrito samples.

    No full text
    <p>The ideogram summarizes the distribution of CNVRs on each human chromosome. The red indicates copy number loss, the blue indicates copy number gain while the green indicates multi-allelic loci.</p

    Candidate genes primer sequences and copy number amplified in SyBr Green qPCR assay.

    No full text
    <p>WDR4 and QCNV4 showed copy number normal and therefore considered as false positive. QCNV2 was detected as a CN gain by microarray, inconsistent with the qPCR validation, therefore considered as false positive. Parentheses, unrounded copy number values calculated using the relative quantification, standard deviation.</p

    Gene Ontology and pathway analyses on the gene set within the Negrito-specific CNVs using PANTHER and DAVID.

    No full text
    <p>(a) PANTHER analysis suggests a major involvement of the genes harboring the population specific CNVs in the immune system process and response to stimulus, as well as the metabolic process; (b) DAVID analysis suggests the involvement of the genes harboring the population specific CNVs in the transcription and regulation of RNA metabolic processes.</p

    Population specific CNVs in 34 genomes of Negrito from Peninsular Malaysia.

    No full text
    <p>Position of CNVs were coordinated based on Human Genome Assembly NCBI (hg18).</p><p>*CNV frequencies calculated based on the 34 Negrito genomes genotyped.</p
    corecore