SIMPLE AND MULTIPLE CROSS-HEDGING OF RICE BRAN

Feasibility of forward pricing sales of rice bran via cross-hedging was investigated. Corn, oats, wheat, and soybean meal futures were considered as simple and multiple cross-hedging media. Simulation results indicated that simple cross-hedging using corn futures would be most effective in reducing price risks.Demand and Price Analysis,

Wilderness and Natural Area Preservation in the United States: A Survey of National Laws

32 pages. Contains 5 pages of endnotes

Wilderness and Natural Area Preservation in the United States: A Survey of National Laws

32 pages. Contains 5 pages of endnotes

Development of a Response Surface Thermal Model for Orion Mated to the International Space Station

A study was performed to determine if a Design of Experiments (DOE)/Response Surface Methodology could be applied to on-orbit thermal analysis and produce a set of Response Surface Equations (RSE) that accurately predict vehicle temperatures. The study used an integrated thermal model of the International Space Station and the Orion Outer mold line model. Five separate factors were identified for study: yaw, pitch, roll, beta angle, and the environmental parameters. Twenty external Orion temperatures were selected as the responses. A DOE case matrix of 110 runs was developed. The data from these cases were analyzed to produce an RSE for each of the temperature responses. The initial agreement between the engineering data and the RSE predictions was encouraging, although many RSEs had large uncertainties on their predictions. Fourteen verification cases were developed to test the predictive powers of the RSEs. The verification showed mixed results with some RSE predicting temperatures matching the engineering data within the uncertainty bands, while others had very large errors. While this study to not irrefutably prove that the DOE/RSM approach can be applied to on-orbit thermal analysis, it does demonstrate that technique has the potential to predict temperatures. Additional work is needed to better identify the cases needed to produce the RSE

The ribosomes of Aspergillus giganteus are sensitive to the cytotoxic action of α-sarcin

AbstractRibosomes in lysates prepared from the mycelia of Aspergillus giganteus MDH 18894, which are actively secreting α-sarcin, do not contain the α-sarcin lesion. However, the addition of exogenous α-sarcin to these same lysates results in cleavage of the 26 S rRNA of the 60 S ribosomal subunit, characteristic of the cytotoxic action of α-sarcin. We conclude that A. giganteus ribosomes are not inherently resistant to the action of α-sarcin but are protected in vivo by producing α-sarcin in an inactive form and/or by the efficient cotranslational secretion of the toxin

The Highly Oscillatory Behavior of Automorphic Distributions for SL(2)

Automorphic distributions for SL(2) arise as boundary values of modular forms and, in a more subtle manner, from Maass forms. In the case of modular forms of weight one or of Maass forms, the automorphic distributions have continuous first antiderivatives. We recall earlier results of one of us on the Holder continuity of these continuous functions and relate them to results of other authors; this involves a generalization of classical theorems on Fourier series by S. Bernstein and Hardy-Littlewood. We then show that the antiderivatives are non-differentiable at all irrational points, as well as all, or in certain cases, some rational points. We include graphs of several of these functions, which clearly display a high degree of oscillation. Our investigations are motivated in part by properties of "Riemann's nondifferentiable function", also known as "Weierstrass' function".Comment: 27 pages, 6 Figures; version 2 corrects misprints and updates reference

Improvements to a Response Surface Thermal Model for Orion

A study was performed to determine if a Design of Experiments (DOE)/Response Surface Methodology could be applied to on-orbit thermal analysis and produce a set of Response Surface Equations (RSE) that predict Orion vehicle temperatures within 10 F. The study used the Orion Outer Mold Line model. Five separate factors were identified for study: yaw, pitch, roll, beta angle, and the environmental parameters. Twenty-three external Orion components were selected and their minimum and maximum temperatures captured over a period of two orbits. Thus, there are 46 responses. A DOE case matrix of 145 runs was developed. The data from these cases were analyzed to produce a fifth order RSE for each of the temperature responses. For the 145 cases in the DOE matrix, the agreement between the engineering data and the RSE predictions was encouraging with 40 of the 46 RSEs predicting temperatures within the goal band. However, the verification cases showed most responses did not meet the 10 F goal. After reframing the focus of the study to better align the RSE development with the purposes of the model, a set of RSEs for both the minimum and maximum radiator temperatures was produced which predicted the engineering model output within +/-4 F. Therefore, with the correct application of the DOE/RSE methodology, RSEs can be developed that provide analysts a fast and easy way to screen large numbers of environments and assess proposed changes to the RSE factors

Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages.

RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.The 54 kDa subunit of the signal recognition particle (SRP54) binds to the signal sequences of nascent secretory and membrane proteins and it contributes to the targeting of these precursors to the membrane of the endoplasmic reticulum (ER). At the ER membrane, the binding of the signal recognition particle (SRP) to its receptor triggers the release of SRP54 from its bound signal sequence and the nascent polypeptide is transferred to the Sec61 translocon for insertion into, or translocation across, the ER membrane. In the current article, we have characterized the specificity of anti-SRP54 autoantibodies, which are highly characteristic of polymyositis patients, and investigated the effect of these autoantibodies on the SRP function in vitro. We found that the anti-SRP54 autoantibodies had a pronounced and specific inhibitory effect upon the translocation of the secretory protein preprolactin when analysed using a cell-free system. Our mapping studies showed that the anti-SRP54 autoantibodies bind to the amino-terminal SRP54 N-domain and to the central SRP54 G-domain, but do not bind to the carboxy-terminal M-domain that is known to bind ER signal sequences. Nevertheless, anti-SRP54 autoantibodies interfere with signal-sequence binding to SRP54, most probably by steric hindrance. When the effect of anti-SRP autoantibodies on protein targeting the ER membrane was further investigated, we found that the autoantibodies prevent the SRP receptor-mediated release of ER signal sequences from the SRP54 subunit. This observation supports a model where the binding of the homologous GTPase domains of SRP54 and the alpha-subunit of the SRP receptor to each other regulates the release of ER signal sequences from the SRP54 M-domain