Radiation from a Charge Uniformly Accelerated for All Time

A recent paper of Singal [Gen. Rel. Grav. 27 (1995), 953-967] argues that a uniformly accelerated particle does not radiate, in contradiction to the consensus of the research literature over the past 30 years. This note points out some questionable aspects of Singal's argument and shows how similar calculations can lead to the opposite conclusion.Comment: LaTeX, 9 pages, to appear in General Relativity and Gravitatio

Distribution Pattern Variability of Granular VRT Applicators

Granular applicators equipped with variable-rate technology (VRT) have gained popularity in recent years as a result of increased interest in variable-rate application. The purpose of this investigation was to characterize distribution patterns at varying rates for different granular applicators. Uniform-rate (UR) tests were conducted to assess the accuracy of variable-rate application from four granular applicators: two spinner-disc spreaders (A and B), and two pneumatic applicators (C and D). Pattern results indicated a consistent triangular pattern for spinner spreader B and consistent patterns for the pneumatic applicators (C and D). However, applicator D produced pattern variations at the center and right side. Simulated overlap analysis generated CVs \u3c 20% for applicators B and C. Applicator A performed well at the two lower rates (CVs \u3c 19%) but not at the highest rate (CV = 27%). Pattern unevenness for applicator D produced CVs between 25% and 34%. The spinner-disc spreaders over-applied, while the pneumatic applicators under-applied at the margins, suggesting an adjustment to the effective swath spacing or spinner-disc speed is needed to improve application accuracy. Further, overlap plots indicated pattern variability even when acceptable CVs were attained for applicators B and C. Therefore, it is recommended that CVs accompany simulated overlap pattern plots to ensure proper calibration of VRT equipment. Swath spacing analysis indicated that three of the four applicator spacings could be changed from the recommended value to improve application uniformity. Pattern comparisons showed that pattern shifts occurred for applicator A (P = 0.0092) with increasing application rate but not for applicators B, C, and D. These results demonstrate potential application errors with VRT and the need for proper calibration to maintain acceptable performance. Further, this investigation demonstrates the need for a VRT equipment testing standard

Rate Response Assessment from Various Granular VRT Applicators

Variable-rate technology (VRT) adds complexity to application equipment, thereby confounding the assessment of applicator performance. The intent of this investigation was to assess the rate response of various VRT granular applicators: two spinner spreaders (A and B), and two pneumatic applicators (C and D). Variable-rate (VR) tests were conducted to quantify the rate response characteristics (delay and transition times) for the applicators. A sigmoidal function was used to model the rate response for five of the six tests. Applicator A exhibited a linear response during decreasing rate changes. Results indicated that only applicator B demonstrated consistent delay and transition times, enabling the use of a single “look-ahead” time for rate response time correction. Contouring of prescription maps increased the transition times for applicator D by enlarging the adjustment area between management zones. Rate changes were quicker for the two newer VR control systems, signifying advancement in hydraulic control valve technology. This research illustrates the need for standard testing protocols for VRT systems to help guide VRT software developers, equipment manufacturers, and end users

Random subspaces for encryption based on a private shared Cartesian frame

A private shared Cartesian frame is a novel form of private shared correlation that allows for both private classical and quantum communication. Cryptography using a private shared Cartesian frame has the remarkable property that asymptotically, if perfect privacy is demanded, the private classical capacity is three times the private quantum capacity. We demonstrate that if the requirement for perfect privacy is relaxed, then it is possible to use the properties of random subspaces to nearly triple the private quantum capacity, almost closing the gap between the private classical and quantum capacities.Comment: 9 pages, published versio

PFD: a database for the investigation of protein folding kinetics and stability

We have developed a new database that collects all protein folding data into a single, easily accessible public resource. The Protein Folding Database (PFD) contains annotated structural, methodological, kinetic and thermodynamic data for more than 50 proteins, from 39 families. A user-friendly web interface has been developed that allows powerful searching, browsing and information retrieval, whilst providing links to other protein databases. The database structure allows visualization of folding data in a useful and novel way, with a long-term aim of facilitating data mining and bioinformatics approaches. PFD can be accessed freely at http://pfd.med.monash.edu.au

A Novel Anti-Inflammatory and Pro-Resolving Role for Resolvin D1 in Acute Cigarette Smoke-Induced Lung Inflammation

Introduction: Cigarette smoke is a profound pro-inflammatory stimulus that contributes to acute lung injuries and to chronic lung disease including COPD (emphysema and chronic bronchitis). Until recently, it was assumed that resolution of inflammation was a passive process that occurred once the inflammatory stimulus was removed. It is now recognized that resolution of inflammation is a bioactive process, mediated by specialized lipid mediators, and that normal homeostasis is maintained by a balance between pro-inflammatory and pro-resolving pathways. These novel small lipid mediators, including the resolvins, protectins and maresins, are bioactive products mainly derived from dietary omega-3 and omega-6 polyunsaturated fatty acids (PUFA). We hypothesize that resolvin D1 (RvD1) has potent anti-inflammatory and pro-resolving effects in a model of cigarette smoke-induced lung inflammation. Methods: Primary human lung fibroblasts, small airway epithelial cells and blood monocytes were treated with IL-1β or cigarette smoke extract in combination with RvD1 in vitro, production of pro-inflammatory mediators was measured. Mice were exposed to dilute mainstream cigarette smoke and treated with RvD1 either concurrently with smoke or after smoking cessation. The effects on lung inflammation and lung macrophage populations were assessed. Results: RvD1 suppressed production of pro-inflammatory mediators by primary human cells in a dose-dependent manner. Treatment of mice with RvD1 concurrently with cigarette smoke exposure significantly reduced neutrophilic lung inflammation and production of pro-inflammatory cytokines, while upregulating the anti-inflammatory cytokine IL-10. RvD1 promoted differentiation of alternatively activated (M2) macrophages and neutrophil efferocytosis. RvD1 also accelerated the resolution of lung inflammation when given after the final smoke exposure. Conclusions: RvD1 has potent anti-inflammatory and pro-resolving effects in cells and mice exposed to cigarette smoke. Resolvins have strong potential as a novel therapeutic approach to resolve lung injury caused by smoke and pulmonary toxicants

Evaluation of the Free Energy of Two-Dimensional Yang-Mills Theory

The free energy in the weak-coupling phase of two-dimensional Yang-Mills theory on a sphere for SO(N) and Sp(N) is evaluated in the 1/N expansion using the techniques of Gross and Matytsin. Many features of Yang-Mills theory are universal among different gauge groups in the large N limit, but significant differences arise in subleading order in 1/N.Comment: 10 pages; no figures; LaTe

The REFOLD database: a tool for the optimization of protein expression and refolding

A large proportion of proteins expressed in Escherichia coli form inclusion bodies and thus require renaturation to attain a functional conformation for analysis. In this process, identifying and optimizing the refolding conditions and methodology is often rate limiting. In order to address this problem, we have developed REFOLD, a web-accessible relational database containing the published methods employed in the refolding of recombinant proteins. Currently, REFOLD contains >300 entries, which are heavily annotated such that the database can be searched via multiple parameters. We anticipate that REFOLD will continue to grow and eventually become a powerful tool for the optimization of protein renaturation. REFOLD is freely available at