27 research outputs found
Nested recursions with ceiling function solutions
Consider a nested, non-homogeneous recursion R(n) defined by R(n) =
\sum_{i=1}^k R(n-s_i-\sum_{j=1}^{p_i} R(n-a_ij)) + nu, with c initial
conditions R(1) = xi_1 > 0,R(2)=xi_2 > 0, ..., R(c)=xi_c > 0, where the
parameters are integers satisfying k > 0, p_i > 0 and a_ij > 0. We develop an
algorithm to answer the following question: for an arbitrary rational number
r/q, is there any set of values for k, p_i, s_i, a_ij and nu such that the
ceiling function ceiling{rn/q} is the unique solution generated by R(n) with
appropriate initial conditions? We apply this algorithm to explore those
ceiling functions that appear as solutions to R(n). The pattern that emerges
from this empirical investigation leads us to the following general result:
every ceiling function of the form ceiling{n/q}$ is the solution of infinitely
many such recursions. Further, the empirical evidence suggests that the
converse conjecture is true: if ceiling{rn/q} is the solution generated by any
recursion R(n) of the form above, then r=1. We also use our ceiling function
methodology to derive the first known connection between the recursion R(n) and
a natural generalization of Conway's recursion.Comment: Published in Journal of Difference Equations and Applications, 2010.
11 pages, 1 tabl
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
Significance arithmetic: the probability of carrying
AbstractIn this paper we develop a number of probabilistic results related to a combinatorial representation of the real number system. This representation employs an algorithmic definition of the arithmetic operations analogous to that used by a computer. A carry function for each place is defined and the distribution of these functions is characterized in terms of classical combinatorial polynomials
On the behavior of a family of meta-Fibonacci sequences
Abstract. A family of meta-Fibonacci sequences is defined by the k-term recursion k−1 � Ta,k(n): = Ta,k(n − i − a − Ta,k(n − i − 1)), n>a+ k, k ≥ 2, i=0 with initial conditions Ta,k(n) = 1 for 1 ≤ n ≤ a + k. Some partial results are obtained for a ≥ 0 and k>1. The case a = 0 and k odd is analyzed in detail, giving a complete characterization of its structure and behavior, marking the first time that such a parametric family of meta-Fibonacci sequences has been solved. This behavior is considerably more complex than that of the more familiar Conolly sequence (a =0,k = 2). Various properties are derived: for example, a certain difference of summands turns out to consist of palindromic subsequences, and the mean values of the functions on these subsequences are computed. Conjectures are made concerning the still more complex behavior of a = 0 and even k>2