7,543 research outputs found

    Evaluating body dissatisfaction as a moderator between physical self-concept and physical activity

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    This article was published in the Spring 2014 issue of the Journal of Undergraduate Researc

    Fluctuations In Body Dissatisfaction Across Social Comparison Situations

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    Body image has been seen traditionally as a stable trait or dispositional construct. However, recent researchers has increasingly recognized a more dynamic aspect of it—one which is likely impacted by various situational factors. One such situational factor is the process of social comparison. As a method of social comparison, clothing size manipulations (such as trying on different sizes of pants) have been shown to affect fluctuations in female participants\u27 body image. Research has also highlighted the detrimental effects of certain visual cues, such as viewing images of slender female figures, on body image. However, there is a lack of research that investigates the impact of these various methods of social comparison. Therefore, the aim of this study was to further the research of clothing size manipulations utilizing a vignette-based methodology while additionally exploring the effects of a visually-cued social comparison in a 3 ( too loose , expected fit , and too tight pants) X 2 ( low BMI vs. high BMI visual) between-subjects design. Manipulation checks were also employed in order to evaluate the participants\u27 memory recall and perceived potency of the vignette. Results showed evidence for a main effect of the pant-size manipulation but neither the visual cue manipulation nor the interaction term were significant. Additionally, the effects of state and trait body dissatisfaction were explored and contrasted. Overall, the findings from this study may be valuable to clinicians looking to structure interventions to improve body image in their clients

    Experimental implementation of bit commitment in the noisy-storage model

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    Fundamental primitives such as bit commitment and oblivious transfer serve as building blocks for many other two-party protocols. Hence, the secure implementation of such primitives are important in modern cryptography. In this work, we present a bit commitment protocol which is secure as long as the attacker's quantum memory device is imperfect. The latter assumption is known as the noisy-storage model. We experimentally executed this protocol by performing measurements on polarization-entangled photon pairs. Our work includes a full security analysis, accounting for all experimental error rates and finite size effects. This demonstrates the feasibility of two-party protocols in this model using real-world quantum devices. Finally, we provide a general analysis of our bit commitment protocol for a range of experimental parameters.Comment: 21 pages (7 main text +14 appendix), 6+3 figures. New version changed author's name from Huei Ying Nelly Ng to Nelly Huei Ying Ng, for consistency with other publication

    Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin.

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    Angiopoietin-like 4 (Angptl4) is a glucocorticoid receptor (GR) primary target gene in hepatocytes and adipocytes. It encodes a secreted protein that inhibits extracellular LPL and promotes adipocyte lipolysis. In Angptl4 null mice, glucocorticoid-induced adipocyte lipolysis and hepatic steatosis are compromised. Markedly, insulin suppressed glucocorticoid-induced Angptl4 transcription. To unravel the mechanism, we utilized small molecules to inhibit insulin signaling components and found that phosphatidylinositol 3-kinase and Akt were vital for the suppression in H4IIE cells. A forkhead box transcription factor response element (FRE) was found near the 15 bp Angptl4 glucocorticoid response element (GRE). Mutating the Angptl4 FRE significantly reduced glucocorticoid-induced reporter gene expression in cells. Moreover, chromatin immunoprecipitation revealed that GR and FoxO1 were recruited to Angptl4 GRE and FRE in a glucocorticoid-dependent manner, and cotreatment with insulin abolished both recruitments. Furthermore, in 24 h fasted mice, significant occupancy of GR and FoxO1 at the Angptl4 GRE and FRE was found in the liver. In contrast, both occupancies were diminished after 24 h refeeding. Finally, overexpression of dominant negative FoxO1 mutant abolished glucocorticoid-induced Angptl4 expression, mimicking the insulin suppression. Overall, we demonstrate that both GR and FoxO1 are required for Angptl4 transcription activation, and that FoxO1 negatively mediates the suppressive effect of insulin

    The experience of long-stay patients in a forensic psychiatric hospital in China: a qualitative study

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    open access articleBackground Long stay in forensic psychiatric hospitals is common in patients who are defined as “not criminally responsible on account of mental disorder”. However, little is known about how these patients experience and perceive the long stay within these settings. The aim of this study is to explore the perception and needs of long-stay patients in forensic psychiatric hospitals in China. Methods In-depth semi-structured interviews were conducted with 21 participants who had lived in the forensic psychiatry hospital for more than 8 years. We used thematic analysis strategies to analyse the qualitative data. Results Participants’ perceptions clustered seven themes: hopelessness, loneliness, worthlessness, low mood, sleep disturbances, lack of freedom, and lack of mental health intervention. Conclusions The views and opinions expressed by long-stay patients showed that psychological distress is prevailing in forensic psychiatric hospitals. Adequate and effective care and mental health interventions are recommended to be tailored for their special needs
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