7,543 research outputs found
Evaluating body dissatisfaction as a moderator between physical self-concept and physical activity
This article was published in the Spring 2014 issue of the Journal of Undergraduate Researc
Fluctuations In Body Dissatisfaction Across Social Comparison Situations
Body image has been seen traditionally as a stable trait or dispositional construct. However, recent researchers has increasingly recognized a more dynamic aspect of it—one which is likely impacted by various situational factors. One such situational factor is the process of social comparison. As a method of social comparison, clothing size manipulations (such as trying on different sizes of pants) have been shown to affect fluctuations in female participants\u27 body image. Research has also highlighted the detrimental effects of certain visual cues, such as viewing images of slender female figures, on body image. However, there is a lack of research that investigates the impact of these various methods of social comparison. Therefore, the aim of this study was to further the research of clothing size manipulations utilizing a vignette-based methodology while additionally exploring the effects of a visually-cued social comparison in a 3 ( too loose , expected fit , and too tight pants) X 2 ( low BMI vs. high BMI visual) between-subjects design. Manipulation checks were also employed in order to evaluate the participants\u27 memory recall and perceived potency of the vignette. Results showed evidence for a main effect of the pant-size manipulation but neither the visual cue manipulation nor the interaction term were significant. Additionally, the effects of state and trait body dissatisfaction were explored and contrasted. Overall, the findings from this study may be valuable to clinicians looking to structure interventions to improve body image in their clients
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Two key events associated with a transposable element burst occurred during rice domestication
Transposable elements shape genome evolution through periodic bursts of amplification. In this study we exploited knowledge of the components of the mPing/Ping/Pong TE family in four rice strains undergoing mPing bursts to track their copy numbers and distribution in a large collection of genomes from the wild progenitor Oryza rufipogon and domesticated Oryza sativa (rice). We characterized two events that occurred to the autonomous Ping element and appear to be critical for mPing hyperactivity. First, a point mutation near the end of the element created a Ping variant ( Ping16A ) with reduced transposition. The proportion of strains with Ping16A has increased during domestication while the original Ping (Ping16G) has been dramatically reduced. Second, transposition of Ping16A into a Stowaway element generated a locus ( Ping16A_Stow ) whose presence correlates with strains that have high mPing copies. Finally, demonstration that Pong elements have been stably silenced in all strains analyzed indicates that sustained activity of the mPing/Ping family during domestication produced the components necessary for the mPing burst, not the loss of epigenetic regulation
Experimental implementation of bit commitment in the noisy-storage model
Fundamental primitives such as bit commitment and oblivious transfer serve as
building blocks for many other two-party protocols. Hence, the secure
implementation of such primitives are important in modern cryptography. In this
work, we present a bit commitment protocol which is secure as long as the
attacker's quantum memory device is imperfect. The latter assumption is known
as the noisy-storage model. We experimentally executed this protocol by
performing measurements on polarization-entangled photon pairs. Our work
includes a full security analysis, accounting for all experimental error rates
and finite size effects. This demonstrates the feasibility of two-party
protocols in this model using real-world quantum devices. Finally, we provide a
general analysis of our bit commitment protocol for a range of experimental
parameters.Comment: 21 pages (7 main text +14 appendix), 6+3 figures. New version changed
author's name from Huei Ying Nelly Ng to Nelly Huei Ying Ng, for consistency
with other publication
Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin.
Angiopoietin-like 4 (Angptl4) is a glucocorticoid receptor (GR) primary target gene in hepatocytes and adipocytes. It encodes a secreted protein that inhibits extracellular LPL and promotes adipocyte lipolysis. In Angptl4 null mice, glucocorticoid-induced adipocyte lipolysis and hepatic steatosis are compromised. Markedly, insulin suppressed glucocorticoid-induced Angptl4 transcription. To unravel the mechanism, we utilized small molecules to inhibit insulin signaling components and found that phosphatidylinositol 3-kinase and Akt were vital for the suppression in H4IIE cells. A forkhead box transcription factor response element (FRE) was found near the 15 bp Angptl4 glucocorticoid response element (GRE). Mutating the Angptl4 FRE significantly reduced glucocorticoid-induced reporter gene expression in cells. Moreover, chromatin immunoprecipitation revealed that GR and FoxO1 were recruited to Angptl4 GRE and FRE in a glucocorticoid-dependent manner, and cotreatment with insulin abolished both recruitments. Furthermore, in 24 h fasted mice, significant occupancy of GR and FoxO1 at the Angptl4 GRE and FRE was found in the liver. In contrast, both occupancies were diminished after 24 h refeeding. Finally, overexpression of dominant negative FoxO1 mutant abolished glucocorticoid-induced Angptl4 expression, mimicking the insulin suppression. Overall, we demonstrate that both GR and FoxO1 are required for Angptl4 transcription activation, and that FoxO1 negatively mediates the suppressive effect of insulin
The experience of long-stay patients in a forensic psychiatric hospital in China: a qualitative study
open access articleBackground
Long stay in forensic psychiatric hospitals is common in patients who are defined as “not criminally responsible on account of mental disorder”. However, little is known about how these patients experience and perceive the long stay within these settings. The aim of this study is to explore the perception and needs of long-stay patients in forensic psychiatric hospitals in China.
Methods
In-depth semi-structured interviews were conducted with 21 participants who had lived in the forensic psychiatry hospital for more than 8 years. We used thematic analysis strategies to analyse the qualitative data.
Results
Participants’ perceptions clustered seven themes: hopelessness, loneliness, worthlessness, low mood, sleep disturbances, lack of freedom, and lack of mental health intervention.
Conclusions
The views and opinions expressed by long-stay patients showed that psychological distress is prevailing in forensic psychiatric hospitals. Adequate and effective care and mental health interventions are recommended to be tailored for their special needs
Media tourism and COVID-19 : An empirical investigation of the impact of COVID-19 on the Scottish tourism industry
Peer reviewedPublisher PD
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