1 research outputs found
Antiproliferative Acetogenins from a <i>Uvaria</i> sp. from the Madagascar Dry Forest
Investigation of the endemic Madagascan plant <i>Uvaria </i>sp<i>.</i> for antiproliferative activity
against the A2780
ovarian cancer cell line led to the isolation of two new acetogenins.
The structures of these two compounds were elucidated on the basis
of analysis of their 1D and 2D NMR spectra, circular dichroism, and
mass spectrometric data, together with chemical modification. The
two acetogenins display weak antiproliferative activity against the
A2780 ovarian cancer, the A2058 melanoma, and the H522 lung cancer
cell lines