Specific mobility questions to children and parents.

<p>Specific mobility questions to children and parents.</p

Flow diagram of the study.

<p>Flow diagram of the study.</p

The effect of training vs. spontaneous adaptation and natural development by age.

<p>Red and blue circles represent performance before (Pre) and after (Post) training, while color-coded arrows indicate individual ST gains after training. The red line is the linear fit between age and ST before training and represents the spontaneous adaptation and natural development in children with HH. The blue line is the linear fit between age and STs <b>after</b> training. The amount of ST improvement obtained by training (delta Y, blue stippled line) is about 130 s (average over all patients) and could theoretically only be achieved after approximately 6 years of spontaneous adaptation (delta X). The green line represents the STs of the healthy children, showing only a small decrease with natural development. Arrows represent individual improvements of the patients before and after training.</p

Schematic representation of the on-screen visual search task during eye tracking.

<p>A: Before each trial, a central cross was presented on a gray background to ensure the subject’s fixation at the center of the screen. A Gabor patch was displayed as an example of the search target: The instruction was “Find the zebra stripes”. B: The children were asked to search the images for the Gabor patch as quickly as possible (here on top of the chimney), and to press the space bar on the keyboard when they found it.</p

Search times during the training paradigm.

<p>In the healthy children of the comparison group, the STs were measured at T1 and T2 without training. The STs did not change by just repeating the task. The patients trained at three different levels of difficulty. The white boxplots show the STs at the beginning, the gray ones at the end of the training period of each level. The medians and IQRs indicate improvement in the patients at all three levels. Outliers were defined as values > 1.5 IQR above the 75% IQR.</p

Search times during a real life search task in the table test.

<p>The median STs for the patients improve significantly from T1 to T3 with p<0.016. T1 = baseline and before training in patients, T2 = after training in patients, T3 = follow-up after 6 weeks.</p

Demographic and clinical data.

<p>Demographic and clinical data.</p

Individual search times and relative improvements at level 1.

<p>Individual search times and relative improvements at level 1.</p