Towards an electrostatic storage ring for fundamental physics measurements

We describe a new table-top electrostatic storage ring concept for $30$ keV polarized ions at frozen spin condition. The device will ultimately be capable of measuring magnetic fields with a resolution of 10$^{-21}$ T with sub-mHz bandwidth. With the possibility to store different kinds of ions or ionic molecules and access to prepare and probe states of the systems using lasers and SQUIDs, it can be used to search for electric dipole moments (EDMs) of electrons and nucleons, as well as axion-like particle dark matter and dark photon dark matter. Its sensitivity potential stems from several hours of storage time, comparably long spin coherence times, and the possibility to trap up to 10$^9$ particles in bunches with possibly different state preparations for differential measurements. As a dark matter experiment, it is most sensitive in the mass range of 10$^{-10}$ to 10$^{-19}$ eV, where it can potentially probe couplings orders of magnitude below current and proposed laboratory experiments.Comment: 5 pages, 4 figures, contribution to the proceedings of the 8th International Symposium on Symmetries in Subatomic Physics (SSP2022

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection are often non-specific, and there is no definitive test for the accurate diagnosis of infection. The 'omics' approaches to identifying biomarkers from the host-response to bacterial infection are promising. In this study, lipidomic analysis was carried out with plasma samples obtained from febrile children with confirmed bacterial infection (n = 20) and confirmed viral infection (n = 20). We show for the first time that bacterial and viral infection produces distinct profile in the host lipidome. Some species of glycerophosphoinositol, sphingomyelin, lysophosphatidylcholine and cholesterol sulfate were higher in the confirmed virus infected group, while some species of fatty acids, glycerophosphocholine, glycerophosphoserine, lactosylceramide and bilirubin were lower in the confirmed virus infected group when compared with confirmed bacterial infected group. A combination of three lipids achieved an area under the receiver operating characteristic (ROC) curve of 0.911 (95% CI 0.81 to 0.98). This pilot study demonstrates the potential of metabolic biomarkers to assist clinicians in distinguishing bacterial from viral infection in febrile children, to facilitate effective clinical management and to the limit inappropriate use of antibiotics

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection ar

Dynamical Transition in Dehydrated Proteins.

Terahertz time-domain spectroscopy and differential scanning calorimetry were used to study the role of the dynamics of biomolecules decoupled from solvent effects. Lyophilized sucrose exhibited steadily increasing absorption with temperature as anharmonic excitations commenced as the system emerged from a deep minimum of the potential energy landscape where harmonic vibrations dominate. The polypeptide bacitracin and two globular proteins, lysozyme and human serum albumin, showed a more complex temperature dependence. Further analysis focused on the spectral signature below and above the boson peak. We found evidence of the onset of anharmonic motions that are characteristic for partial unfolding and molecular jamming in the dry biomolecules. The activation of modes of the protein molecules at temperatures comparable to the protein dynamical transition temperature was observed in the absence of hydration. No evidence of Fröhlich coherence, postulated to facilitate biological function, was found in our experiments

The protein dynamical transition is independent of hydration

Terahertz time-domain spectroscopy and differential scanning calorimetry were used to study the role of the dynamics of biomolecules decoupled from solvent effects. Lyophilised sucrose exhibited steadily increasing absorption with temperature as anharmonic excitations commence as the system emerges from a deep minimum of the potential energy landscape where harmonic vibrations dominate. The polypeptide bacitracin and two globular proteins, lysozyme and human serum albumin, showed a more complex temperature dependence. Further analysis focused on the spectral signature below and above the boson peak. We found evidence for the onset of anharmonic motions that are characteristic for partial unfolding and molecular jamming in the dry biomolecules. The activation of modes of the protein molecules at temperatures comparable to the protein dynamical transition temperature was observed in the absence of hydration. No evidence for Fr\"ohlich coherence, postulated to facilitate biological function, was found in our experiments

Dynamical Transition in Dehydrated Proteins.

Publication status: PublishedTerahertz time-domain spectroscopy and differential scanning calorimetry were used to study the role of the dynamics of biomolecules decoupled from solvent effects. Lyophilized sucrose exhibited steadily increasing absorption with temperature as anharmonic excitations commenced as the system emerged from a deep minimum of the potential energy landscape where harmonic vibrations dominate. The polypeptide bacitracin and two globular proteins, lysozyme and human serum albumin, showed a more complex temperature dependence. Further analysis focused on the spectral signature below and above the boson peak. We found evidence of the onset of anharmonic motions that are characteristic for partial unfolding and molecular jamming in the dry biomolecules. The activation of modes of the protein molecules at temperatures comparable to the protein dynamical transition temperature was observed in the absence of hydration. No evidence of Fröhlich coherence, postulated to facilitate biological function, was found in our experiments

Zur Kulturpolitik der UdSSR in Österreich 1945 bis 1955 : Musik als Repräsentationsmittel und ihre Auswirkungen auf österreichische Russlandbilder

Nach der Einnahme Wiens durch die Rote Armee am 13. April 1945 wurde auf dem Wiener Rathaus die sowjetische Flagge gehisst. Dies bedeutete nicht nur die Befreiung Österreichs von der nationalsozialistischen Herrschaft und die Wiederherstellung seiner staatlichen Existenz, sondern auch den Beginn einer zehn Jahre dauernden alliierten Besatzung..