Improving Our Sink or Swim Training Model for Church Planters

Many of those sent out locally or internationally to plant churches have never planted a church or been involved in the process, worked on a team, or have been trained in crosscultural studies. This paper argues that we can do a much better job of preparing our church planters

Big Picture Curricula for Multiethnic Ministry

This article will propose a storied, big-picture approach to multiethnic ministry. It will advocate curriculum that builds a cathedral rather than isolated rooms. Before considering story-based, big-picture curricula I will first look at how the multiethnic church, and other types of churches, relates to the dominate theological themes of unity and diversity

Improving Our Sink or Swim Training Model for Church Planters

Many of those sent out locally or internationally to plant churches have never planted a church or been involved in the process, worked on a team, or have been trained in crosscultural studies. This paper argues that we can do a much better job of preparing our church planters

Big Picture Curricula for Multiethnic Ministry

This article will propose a storied, big-picture approach to multiethnic ministry. It will advocate curriculum that builds a cathedral rather than isolated rooms. Before considering story-based, big-picture curricula I will first look at how the multiethnic church, and other types of churches, relates to the dominate theological themes of unity and diversity

Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p

AbstractWe have reproduced the posttranslational mode of protein translocation across the endoplasmic reticulum membrane with reconstituted proteoliposomes containing a purified complex of seven yeast proteins. This Sec complex includes a heterotrimeric Sec61p complex, homologous to that in mammals, as well as all other membrane proteins found in genetic screens for translocation components. Efficient posttranslational translocation also requires the addition of lumenal Kar2p(BIP) and ATP. The trimeric Sec61p complex also exists as a separate entity that, in contrast with the large Sec complex, is associated with membrane-bound ribosomes. We therefore hypothesize that distinct membrane protein complexes function in co- and posttranslational translocation pathways

Investigation of congestive heart failure in beef cattle in a feedyard at a moderate altitude in western Nebraska

Right-sided congestive heart failure (brisket disease) commonly occurs in cattle raised at elevations \u3e2,500– 3,500 m. We investigated clinical cases resembling brisket disease at a western Nebraska feedyard at a moderate altitude (1,369 m). Over a 15-mo period (2009–2010), we examined 17 cases (16 steers and 1 heifer), all purebred Angus. All animals had clinical right-sided heart failure: brisket and ventral abdominal edema, and severe chronic passive congestion of the liver. Gross examination confirmed right ventricular hypertrophy (left ventricle plus septum: right ventricle weight ratio mean: 1.33 vs. 2.8–4.0 reference interval). Microscopically, all 17 cases had interstitial fibrosis (mean score: 2.4 ± 0.8) and 6 had replacement fibrosis of the right ventricle, whereas 14 had interstitial fibrosis (mean score: 1.2 ± 0.2) and 0 had replacement fibrosis of the left ventricle. Lesions of arteriosclerosis were seen in 9 of 16 cases in 51 of 571 (8.9%) right ventricular coronary arteries, and in 10 of 16 cases in 52 of 366 (14.2%) left ventricular coronary arteries. The probability of coronary arteriosclerosis was greater in papillary ventricular muscle (OR = 11.3; p \u3c 0.0001), left ventricle (OR = 4.8; p \u3c 0.0001), and larger arteries (OR = 1.01; p \u3c 0.0001). Pulmonary arteries and arterioles had lesions compatible with hypoxia-induced pulmonary hypertension. We hypothesize that moderate hypobaric conditions significantly contributed to disease in cattle genetically predisposed to hypoxia-induced pulmonary hypertension. Adiposity, coronary arteriosclerosis, and left ventricular fibrosis may have contributed to the condition; however, the cattle died prior to development of advanced obesity