学会抄録

Canonical pathways enrichment calculated by Ingenuity Pathway Analysis. A total of 46 pathways were detected as significantly enriched with genes differentially expressed in the pairwise comparisons indicated in the first row of the table (P < 0.05). First column on the left indicates Gene Ontology name associated with the canonical pathway. Log10P values are reported for each pathway. (XLS 38 kb

What is the influence of cultural capital on student reading achievement in Confucian as compared to non-Confucian heritage societies?

Preterm birth does not associate with vaginal dysbiosis at 16 weeks of gestation. (A) Heatmap of ward hierarchical clustering of microbial genera from 161 women sampled at 16 weeks of gestation, classified according to subsequent gestation at delivery. Women delivering preterm both <34+0 weeks (n = 18, red) and 34+0 to 36+6 weeks (n = 16, orange) had a predominantly Lactobacillus species-dominated vaginal microbiome, as did women experiencing term births >37+0 weeks (n = 127, gray). (B) No correlation between richness (number of bacterial species observed; S obs) (C), nor alpha diversity as measured using the Shannon index with gestation at birth was observed. (ns non-significant, 2-way ANOVA)

Additional file 13: of The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk

Comparison of mean L. iners and L. crispatus relative abundance in control (n = 42) versus progesterone groups (n = 25) and as a function of birth before and after 34 weeks. (A) Prior to progesterone intervention at <18-week sampling, women with a short CL <25 mm had greater relative abundance of L. iners compared to controls, and lower L. crispatus (B) although this did not reach significance. L. iners abundance declined in both control and progesterone groups towards 34 weeks of sampling while mean L. crispatus abundance increased (ANOVA, K-W, Dunn’s multiple comparison). Inclusive of control and progesterone groups, preterm birth <34 weeks was associated with higher mean L. iners abundance at longitudinal sampling (C; P < 0.05), and lower mean L. crispatus abundance (D; P < 0.001) than deliveries >34 weeks, at matched gestational age at sampling throughout follow-up (Welch’s t test)

Patient characteristics for women that delivered at term without cerclage (Group 1) and women that had cerclage or delivered prematurely (Group 2).

<p>Patient characteristics for women that delivered at term without cerclage (Group 1) and women that had cerclage or delivered prematurely (Group 2).</p

Preterm Birth Prevention Post-Conization: A Model of Cervical Length Screening with Targeted Cerclage - Fig 2

<p><b>Mean difference in CL (mean % Δ CL) between time-points A: 13+0–15+6 weeks, B: 16+0–18+6 weeks, C: 20+0–22+6 weeks (A-B, B-C, and A-C) according to delivery outcome and cerclage insertion.</b> In women receiving a cerclage, mean CL started above 25mm at timepoint A, and went on to shorten, most significantly at timepoint C. The greatest difference in CL is observed between timepoints B-C and A-C in those that received a cerclage and went on to deliver preterm <37weeks, followed by term delivery with a cerclage. (<i>% ΔCL = percentage change in CL (mm) between screening time points; PTB = preterm birth <37 weeks; Screening time points = A</i>: <i>13+0–15+6 weeks</i>, <i>B</i>: <i>16+0–18+6 weeks</i>, <i>C</i>: <i>20+0–22+6 weeks; SD = standard deviation; Term = birth >37 weeks; W = weeks)</i>.</p

Mean CL (mm)(SD) at screening time-points A, B, C and mean percentage ΔCL (SD) between screening time-points A-B, B-C, and A-C for Group 1 and 2.

<p>Mean CL (mm)(SD) at screening time-points A, B, C and mean percentage ΔCL (SD) between screening time-points A-B, B-C, and A-C for Group 1 and 2.</p

Risk of preterm birth by change in cervical length (mm) after cerclage insertion.

<p>The relative risk of preterm birth before 34 and 37 weeks gestation is shown in women who did not demonstrate cervical lengthening, or indeed shortened, after cerclage insertion, relative to those whose cervical lengths increased post cerclage procedure.</p

Sensitivity, specificity, likelihood ratios, and positive and negative predictive values for cerclage intervention and/or preterm birth <37 weeks, for screening time-points A, B and C, and percentage difference in CL between screening time-points A, B and C.

<p>Sensitivity, specificity, likelihood ratios, and positive and negative predictive values for cerclage intervention and/or preterm birth <37 weeks, for screening time-points A, B and C, and percentage difference in CL between screening time-points A, B and C.</p

Preterm birth rates: A in the UK; B in the local population (three study units); C estimated in women post-cervical treatment based on UK rates; D in this study cohort.

<p>Preterm birth rates: A in the UK; B in the local population (three study units); C estimated in women post-cervical treatment based on UK rates; D in this study cohort.</p

Risk of preterm birth by height of cerclage as a percentage of cervical length.

<p>The relative risk of preterm birth before 34 and 37 weeks of gestation is shown in women with cerclages placed in the distal half (represented as < 50% height) of the cervix relative to those with cerclages placed in the proximal half (represented as > 50%).</p